Protective effects of leaf extract of Zanthoxylum ailanthoides on oxidation of low-density lipoprotein and accumulation of lipid in differentiated THP-1 cells

Food and Chemical Toxicology

Volumn 47, Issue 6, 2009, Pages 1265-1271

  Chu, Chin Ying ^a   Lee, Huei Jane ^a   Chu, Chia Yih ^a   Yin, Yu Fang ^a   Tseng, Tsui Hwa ^a  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Flavonoid; LDL; Oxidation; Zanthoxylum ailanthoides

Indexed keywords

ALCOHOL; ALKADIENE; APOLIPOPROTEIN B100; CD36 ANTIGEN; COPPER SULFATE; GLYCOSIDE; HYPERIN; LOW DENSITY LIPOPROTEIN; PLANT EXTRACT; RUTOSIDE; SCAVENGER RECEPTOR A; SCAVENGER RECEPTOR B; SCAVENGER RECEPTOR CLASS A1; THIOBARBITURIC ACID DERIVATIVE; UNCLASSIFIED DRUG; ZANTHOXYLUM AILANTHOIDES EXTRACT;

ADULT; ARTICLE; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; FEMALE; FRAGMENTATION REACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIPID OXIDATION; LIPID STORAGE; LIPID TRANSPORT; MACROPHAGE; MEDICINAL PLANT; NORMAL HUMAN; PLANT LEAF; PROTECTION; ZANTHOXYLUM AILANTHOIDES;

ADULT; ANTIGENS, CD36; ANTIOXIDANTS; APOLIPOPROTEINS B; BLOTTING, WESTERN; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COPPER SULFATE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; FLAVONOIDS; HUMANS; LIPID METABOLISM; MALE; MASS SPECTROMETRY; OXIDATION-REDUCTION; PLANT EXTRACTS; PLANT LEAVES; RECEPTORS, LDL; SCAVENGER RECEPTORS, CLASS A; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; THIOBARBITURIC ACID REACTIVE SUBSTANCES; YOUNG ADULT; ZANTHOXYLUM;

ZANTHOXYLUM AILANTHOIDES;

EID: 67349165059     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.02.020     Document Type: Article

References (23)

1. Carini M., Aldini G., Orioli M., and Facino R.M. Antioxidant and photoprotective activity of a lipophilic extract containing neolignans from Krameria triandra roots. Planta Med. 68 (2002) 193-197
2. Cheng M.J., Lee K.H., Tsai I.L., and Chen I.S. Two new sesquiterpenoids and anti-HIV principles from the root bark of Zanthoxylum ailanthoides. Bioorg. Med. Chem. 13 (2005) 5915-5920
3. Chung Y.C., Chien C.T., Teng K.Y., and Chou S.T. Antioxidative and mutagenic properties of Zanthoxylum ailanthoides Sieb & zucc. Food Chem. 97 (2006) 418-425
4. Craigo J., Callahan M., Huang R.C.C., and DeLucia A.L. Inhibition of human papillomavirus type 16 gene expression by nordihydroguaiaretic acid plant lignan derivatives. Antiviral Res. 47 (2000) 19-28
5. Davies M.J., Richardson P.D., and Woolf N. Risk of thrombosis in human atherosclerotic plaques: role of extracellular lipid, macrophage, and smooth muscle cell content. Br. Heart J. 69 (1993) 377-381
6. Day S.H., Chiu N.Y., Tsao L.T., Wang J.P., and Lin C.N. New lignan glycosides with potent antiinflammatory effect, isolated from Justicia ciliata. J. Nat. Prod. 63 (2000) 1560-1562
7. Eguchi A., Murakami A., and Ohigashi H. Nobiletin, a citrus flavonoid, suppresses phorbol ester-induced expressin of multiple scavenger receptor genes in THP-1 human monocytic cells. FEBS Lett. 580 (2006) 3321-3328
8. Endemann G., Stanton L.W., Madden K.S., Bryant C.M., White R.T., and Protter A.A. CD36 is a receptor for oxidized low density lipoprotein. J. Biol. Chem. 268 (1993) 11811-11816
9. Glass C.K., and Witztum J.L. Atherosclerosis: the road ahead. Cell 104 (2001) 503-516
10. Geleijnse J.M., Launer L.J., Van der Kuip D.A., Hofman A., and Witteman J.C. Inverse association of tea and flavonoid intakes with incident myocardial infarction: the Rotterdam study. Am. J. Clin. Nutr. 75 (2002) 880-886
11. Heidemann C., Schulze M.B., Franco O.H., van Dam R.M., Mantzoros C.S., and Hu F.B. Dietary patterns and risk of mortality from cardiovascular disease, cancer, and all causes in a prospective cohort of women. Circulation 118 (2008) 230-237
12. Heinecke J.W. Lipoprotein oxidation in cardiovascular disease: chief culprit or innocent bystander?. J. Exp. Med. 203 (2006) 813-816
13. Helen V., Lisa P., Tracey L.G., Guennadi A.K., Alexander H., Colin H.M., Ivan P., Stephen A.S., Keith E.S., Wolf C.R., and Colin N.A.P. The peroxisome proliferator-activated receptor (promotes lipid accumulation in human macrophages. J. Biol. Chem. 276 (2001) 44258-44265
14. Hertog M.G., Feskens E.J., Hollman P.C., Katan M.B., and Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly study. Lancet 342 (1993) 1007-1011
15. Kawaii S., Tomono Y., Katase E., Ogawa K., and Yano M. Quantitation of flavonoid constituents in citrus fruits. J. Agric. Food Chem. 47 (1999) 3565-3571
16. Kawai Y., Nishkawa T., Shiba Y., Saito S., Murota K., Shibata N., Kobayashi M., Kanayama M., Uchida K., and Terao J. Macrophage as a target of quercetin glucuronides in human atherosclerotic arteries. J. Biol. Chem. 283 (2008) 9424-9434
17. Lambert J.D., Meyers R.O., Timmermann B.N., and Dorr R.T. Tetra-O-methyl- nordihydroguaiaretic acid inhibits melanoma in vivo. Cancer Lett. 171 (2001) 47-56
18. Mink P.J., Scrafford C.G., Barraj L.M., Harnack L., Hong C.P., Nettleton J.A., and Jacobs Jr. D.J. Flavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women. Am. J. Clin. Nutr. 85 (2007) 895-909
19. Moore K.J., and Freeman M.W. Scavenger receptors in atherosclerosis. Arterioscler. Thromb. Vase Biol. 26 (2006) 1702-1711
20. Rusinol A.E., Yang L., Thewke D., Panini S.R., Kramer M.F., and Sinensky M.S. Isolation of a somatic cell mutant resistant to the induction of apoptosis by low density lipoprotein. J. Biol. Chem. 275 (2000) 7296-7303
21. Sato T., Nagata M., and Engle L.M. Evaluation of antioxidant activity of indigenous vegetables from South and Southeast Asia. JIRCAS Res. Highlights (2002) 10-11
22. Sugano R., Yamamura T., Harada-Shiba M., Miyake Y., and Yamamoto A. Uptake of oxidized low-density lipoprotein in a THP-1 cell line lacking scavenger receptor A. Atherosclerosis 158 (2001) 351-357
23. Wallin B., Rosengren B., Shertzer H.G., and Camejo G. Lipoprotein oxidation and measurement of thiobarbituric acid reacting substances formation in a single microtiter plate: its use for evaluation of antioxidants. Analy. Biochem. 208 (1993) 10-15