YS 51, 1-(β-naphtylmethyl)-6,7-dihydroxy-1,2,3,4,-tetrahydroisoquinoline, protects endothelial cells against hydrogen peroxide-induced injury via carbon monoxide derived from heme oxygenase-1

Biochemical Pharmacology

Volumn 74, Issue 9, 2007, Pages 1361-1370

  Heo, Ja Myung ^a   Kim, Hye Jung ^a   Ha, Yu Mi ^a   Park, Min Kyu ^a   Kang, Young Jin ^b   Lee, Young Soo ^a   Seo, Han Geuk ^a   Lee, Jae Heun ^a   Yun Choi, Hye Sook ^c   Chang, Ki Churl ^a  

^a Gyeongsang National University School of Medicine   (South Korea)

^b Yeungnam University College of Medicine   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Antioxidant; Carbon monoxide; Endothelial cell; Heme oxygenase 1; Oxidative injury; Reactive oxygen species; YS 51

Indexed keywords

1 (BETA NAPHTHYLMETHYL) 6,7 DIHYDROXY 1,2,3,4 TETRAHYDROISOQUINOLINE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BILIRUBIN; CARBON MONOXIDE; DEFEROXAMINE; HEME OXYGENASE 1; HEMIN; HYDROGEN PEROXIDE; ISOQUINOLINE DERIVATIVE; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXYHEMOGLOBIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTOPORPHYRIN ZINC; REACTIVE OXYGEN METABOLITE; RUBIDIUM; UNCLASSIFIED DRUG; YS 51;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL DEATH; CELL PROTECTION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME ASSAY; GENE INDUCTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTIOXIDANTS; BLOTTING, WESTERN; CARBON MONOXIDE; CATTLE; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; HEME OXYGENASE-1; HYDROGEN PEROXIDE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TETRAHYDROISOQUINOLINES;

EID: 34548860110     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.07.023     Document Type: Article

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