Murine Pkd1 is a developmentally regulated gene from morula to adulthood: Role in tissue condensation and patterning

Developmental Dynamics

Volumn 214, Issue 4, 1999, Pages 337-348

  Guillaume, Richard ^a   D'Agati, Vivette ^b   Daoust, Martin ^a   Trudel, Marie ^a,c  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^b Columbia University ^*  (United States)

^c NONE   (Canada)

Author keywords

Mesenchymal condensation; Metanephric blastema; Neural crest cells; Pkd1; Tubulogenesis

Indexed keywords

POLYCYSTIN; RNA;

ADOLESCENT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLADDER; CONTROLLED STUDY; EMBRYO; FEMALE; GASTRULATION; GENE EXPRESSION REGULATION; GENE MUTATION; KIDNEY DEVELOPMENT; KIDNEY POLYCYSTIC DISEASE; KIDNEY TUBULE; LUNG DEVELOPMENT; MESENCHYME; MORULA; MOUSE; NEURAL CREST; NEURAL TUBE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SALIVARY GLAND;

ANIMALS; BLOTTING, SOUTHERN; BODY PATTERNING; CLONING, MOLECULAR; DNA, COMPLEMENTARY; FLUORESCENT ANTIBODY TECHNIQUE; GASTRULA; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; IN SITU HYBRIDIZATION; MICE; MODELS, GENETIC; NEURAL CREST; OOCYTES; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, NUCLEIC ACID; STEM CELLS; TIME FACTORS; TISSUE DISTRIBUTION; TRPP CATION CHANNELS;

EID: 0032955309     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0177(199904)214:4<337::AID-AJA6>3.0.CO;2-O     Document Type: Article

References (32)

1. Beaumont A, Cassier P. 1987. Biologie animale, les cordes anatomie comparee des vertebres. Paris: Dunod Université.
2. Brasier JL, Henske EP. 1997. Loss of the polycystic kidney disease (PKD1) region of chromosome 16p13 in renal cyst cells supports a loss-of-function model for cyst pathogenesis. J Clin Invest 99:194-199.
3. Burn TC, Connors TD, Dackowski WR, Petry LR, Van Raay TJ, Millholland JM, Venet M, Miller G, Hakim RM, Landes GM, Klinger KW, Qian F, Onuchic LF, Watnick T, Germino GG, Doggett NA. 1995. Analysis of the genomic sequence for the autosomal dominant polycystic kidney disease (PKD1) gene predicts the presence of a leucine-rich repeat. Hum Mol Genet 4:575-582.
4. Chomczynski P, Sacchi N. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
5. Consortium EPKD. 1994. The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. Cell 77:881-894.
6. Consortium IPKD. 1995. Polycystic kidney disease: the complete structure of the PKD1 gene and its protein. Cell 81:289-298.
7. Daoust M, Reynolds D, Bichet DG, Somlo S. 1995. Evidence for a third Genetic locus for autosomal dominant polycystic kidney disease. Genomics 25:733-736.
8. Geng L, Segal Y, Pavlova A, Barros EJG, Löhning C, Lu W, Nigam SK, Frischauf A-M, Reeders ST, Zhou J. 1997. Distribution and developmentally regulated expression of murine polycystin. Am J Physiol 272:F451-F459.
9. Gilbert SF. 1994. Developmental Biology. Sunderland: Sinauer Associates.
10. Griffin MD, O'Sullivan DA, Torres VE, Grande JP, Kanwar YS, Kumar R. 1997, Expression of polycystin in mouse metanephros and extra-metanephric tissues. Kidney Int 52:1196-1205.
11. Grobstein C. 1955. Inductive interaction in the development of the mouse metanephros. J Exp Zool 130:319-339.
12. Hogan B, Costantini F, Lacy E. 1986. Manipulating the mouse embryo. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
13. Hughes J, Ward CJ, Peral B, Aspinwall R, Clark K, San Millan JL, Gamble V, Harris PC. 1995. The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains. Nature Genet 10:151-160.
14. Ibraghimov-Beskrovnaya O, Dackowski WR, Foggensteiner L, Coleman N, Thiru S, Petry LR, Burn TC, Connors TD, Van Raay T, Bradley J, Qian F, Onuchic LF, Watnick TJ, Piontek K, Hakim RM, Landes GM, Germino GG, Sandford R, Klinger KW. 1997. Polycystin: in vitro synthesis, in vivo tissue expression, and subcellular localization identifies a large membrane-associated protein. Proc Natl Acad Sci USA 94:6397-6402.
15. Lanoix J, D'Agati V, SzaboLcs M, Trudel M. 1996. Dysregulation of cellular proliferation and apoptosis mediates human autosomal dominant polycystic kidney disease (ADPKD). Oncogene 13:1153-1160.
16. Le Douarin N. 1982. The neural crest. New York: Cambridge University Press.
17. Löhning C, Nowicka U, Frischauf A-M. 1997. The mouse homolog of PKD1: sequence analysis and alternative splicing. Mammal Genome 8:307-311.
18. Lu W, Peissel B, Babkhanlou H, Pavlova A, Geng L, Fan X, Larson C, Brent G, Zhou J. 1997. Perinatal lethality with kidney and pancreas defects in mice with a targetted PKD1 mutation. Nature Genet 17:179-181.
19. Mochizuki T, Wu G, Hayashi T, Xenophontos S, Veldhuisen B, Saris JJ, Reynolds DM, Cai Y, Gabow PA, Pierides A, Kimberling WJ, Breuning MH, Deltas CC, Peters DJM, Somlo S. 1996. PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein. Science 272:1339-1342.
20. Olsson PG, Lohning C, Horsley S, Kearney L, Harris PC, Frischauf A-M. 1996. The mouse homologue of the Polycystic Kidney Disease gene (Pkd1) is a single-copy gene. Genomics 34:233-235.
21. Palson R, Sharma CP, Kim K, McLaughlin M, Brown D, Arnaout MA. 1996. Characterization and cell distribution of polycystin, the product of autosomal dominant polycystic kidney disease gene 1 Mol Med 2:702-711.
22. Qian F, Watnick TJ, Onuchic LF, Germino GG. 1996. The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease type I. Cell 87:979-987.
23. Qian F, Germino FJ, Cai Y, Zhang X, Somlo S, Germino GG. 1997. PKD1 interacts with PKD2 through a probable coiled-coil domain. Nature Genet 16:179-183.
24. Sandford R, Sgotto B, Aparicio S, Brenner S, Vaudin M, Wilson RK, Chissoe S, Pepin K, Bateman A, Chothia C, Hughes J, Harris P. 1997. Comparative analysis of the polycystic kidney disease 1 (PKD1) gene reveals an integral membrane glycoprotein with multiple evolutionary conserved domains. Hum Mol Genet 6:1483-1489.
25. Trudel M, D'Agati V, Costantini F. 1991. C-myc as an inducer of polycystic kidney disease in transgenic mice. Kidney Int 39:665-671.
26. Trudel M, Chretien N, D'Agati V. 1994. Disappearance of polycystic kidney disease in revertant c-myc transgenic mice. Mammal Genome 5:149-152.
27. Trudel M, Lanoix J, Barisoni J, Blouin M-J, Desforges M, L'Italien C, D'Agati V. 1997. C-MYC-induced Apoptosis in Polycystic Kidney Disease is Bcl-2 and p53 Independent. J Exp Med 186:1873-1884.
28. Trudel M, Barisoni L, Lanoix J , D'Agati V. 1998. Polycystic kidney disease in SBM transgenic mice: role of c-myc in disease induction and progression. Am J Pathol 152:219-229.
29. Tsiokas L, Kim E, Arnould T, Sukhatme VP, Walz G. 1997. Homo- and heterodimeric interactions between the gene product of PKD1 and PKD2. Proc Natl Acad Sci USA 94:6965-6970.
30. Unsworth B, Grobstein C. 1970. Induction of kidney tubules in mouse metanephrogenic mesenchyme by various embryonic mesenchymal tissues. Dev Biol 21:547-556.
31. Van Adelsberg J, Chamberlain S, D'Agati V. 1997. Polycystin expression is temporally and spatially regulated during renal development. Am J Physiol 272:F602-F609.
32. Ward CJ, Turley H, Ong ACM, Comley M, Biddolph S, Chetty R, Ratcliffe PJ, Gatter K, Harris PC. 1996. Polycystin, the polycystic kidney disease 1 protein, is expressed by epithelial cells in fetal, adult and polycystic kidney. Proc Natl Acad Sci USA 93:1524-1528.