Synthesis and structure analysis of cyclodehydration product of piroxicam: A metabolite detected in dogs and monkeys

European Journal of Medicinal Chemistry

Volumn 44, Issue 8, 2009, Pages 3368-3371

  Pal, Sarbani ^a   Bindu, P ^a   Dubey, P K ^a   Chakraborty, Santu ^b   Mukherjee, Alok Kumar ^b  

^a JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY   (India)

^b JADAVPUR UNIVERSITY   (India)

Author keywords

Cyclodehydration; Piroxicam; Single crystal; X ray

Indexed keywords

6 METHYL 6H 7 OXOPYRIDO[1,2 A]PYRIMIDO[5,4 C] 1,2 BENZOTHIAZINE 5,5 DIOXIDE; BENZENECARBONYL CHLORIDE; CHLORIDE; DRUG METABOLITE; MELOXICAM; OXICAM DERIVATIVE; PIROXICAM; TRIETHYLAMINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BENZOYLATION; CHEMICAL MODIFICATION; CONTROLLED STUDY; CYCLODEHYDRATION; DOG; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGEN BOND; MONKEY; NONHUMAN; X RAY CRYSTALLOGRAPHY;

ACETATES; ANIMALS; CRYSTALLOGRAPHY, X-RAY; DOGS; HAPLORHINI; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PIROXICAM; SPECTRUM ANALYSIS; WATER;

EID: 67349149369     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.03.010     Document Type: Article

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