Optimisation and molecular signalling of apoptosis in sequential cryotherapy and chemotherapy combination in human A549 lung cancer xenografts in SCID mice

British Journal of Cancer

Volumn 100, Issue 12, 2009, Pages 1896-1902

  Forest, V ^a   Hadjeres, R ^b   Bertrand, R ^a,c   Jean Francois R ^b,c  

^a Institut du Cancer de Montreal   (Canada)

^b NOTRE DAME HOSPITAL   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Bcl 2 family; Chemotherapy; Combination treatment; Cryotherapy; Lung cancer

Indexed keywords

BH3 PROTEIN; BIM PROTEIN; MESSENGER RNA; NAVELBINE; NITROUS OXIDE; PROTEIN BIM EL; PROTEIN MCL 1; PROTEIN NOXA; PUMA PROTEIN; UNCLASSIFIED DRUG; VINORELBINE DITARTRATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CELL STRAIN; CONTROLLED STUDY; CORRELATION ANALYSIS; CRYOSURGERY; GROWTH INHIBITION; HUMAN; HUMAN CELL; LUNG CANCER; MALE; MOUSE; MULTIMODALITY CANCER THERAPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCID MOUSE; SEQUENTIAL MULTIMODALITY CANCER THERAPY; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; TREATMENT RESPONSE; TUMOR VOLUME; TUMOR XENOGRAFT;

EID: 67349142635     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6605046     Document Type: Article

References (25)

1. Adams JM, Cory S (2007) The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 26: 1324-1337
2. Baust JG, Gage AA, Clarke D, Baust JM, Van Buskirk R (2004) Cryosurgery a putative approach to molecular-based optimization. Cryobiology 48: 190-204
3. Benson JW (1975) Combined chemotherapy and cryosurgery for oral cancer. Am J Surg 130: 596-600
4. Clarke DM, Hollister WR, Baust JG, Van Buskirk RG (1999) Cryosurgical modeling: sequence of freezing and cytotoxic agent application affects cell death. Mol Urol 3: 25-31
5. Clarke DM, Baust JM, Van Buskirk RG, Baust JG (2001) Chemo-cryo combination therapy: an adjunctive model for the treatment of prostate cancer. Cryobiology 42: 274-285
6. Clarke DM, Baust JM, Van Buskirk RG, Baust JG (2004) Addition of anticancer agents enhances freezing-induced prostate cancer cell death: implications of mitochondrial involvement. Cryobiology 19: 45-61
7. Forest V, Peoc'h M, Campos L, Guyotat D, Vergnon JM (2005a) Effects of cryotherapy or chemotherapy on apoptosis in a non-small-cell lung cancer xenografted into SCID mice. Cryobiology 50: 29-37
8. Forest V, Peoc'h M, Ardiet C, Campos L, Guyotat D, Vergnon JM (2005b) In vivo cryochemotherapy of a human lung cancer model. Cryobiology 51: 92-101
9. Forest V, Peoc'h M, Campos L, Guyotat D, Vergnon JM (2006) Benefit of a combined treatment of cryotherapy and chemotherapy on tumour growth and late cryo-induced angiogenesis in a non-small-cell lung cancer model. Lung Cancer 54: 79-86
10. Gage AA, Baust J (1998) Mechanisms of tissue injury in cryosurgery. Cryobiology 37: 171-186
11. Hanai A, Yang WL, Ravikumar TS (2001) Induction of apoptosis in human colon carcinoma cells HT29 by sublethal cryo-injury: mediation by cytochrome c release. Int J Cancer 93: 526-533
12. Homasson JP, Pecking A, Roden S, Angebault M, Bonniot JP (1992) Tumour fixation of bleomycin labeled with 57 cobalt before and after cryotherapy of bronchial carcinoma. Cryobiology 29: 543-548
13. Ikekawa S, Ishihara K, Tanaka S, Ikeda S (1985) Basic studies of cryochemotherapy in a murine tumour system. Cryobiology 22: 477-483
14. Korpan NN (2001) Indications of cryosurgery in pulmonology. In: Basics of cryosurgery. Springer-Verlag:Vienna, Austria, pp 181-187
15. Korsmeyer SJ, Shutter JR, Veis DJ, Merry DE, Oltvai ZN (1993) Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death. Semin Cancer Biol 4: 327-332
16. Le Pivert P, Haddad RS, Aller A, Titus K, Doulat J, Renard M, Morrisson DR (2004) Ultrasound guided combined cryoablation and microencapsulated 5-fluorouracil inhibits growth of human prostate tumours in xenogenic mouse model assessed by luminescence imaging. Technol Cancer Res Treat 3: 135-142
17. Maiwand MO, Homasson JP (1995) Cryotherapy for tracheobronchial disorders. Clin Chest Med 16: 427-443
18. Mir LM, Rubinsky B (2002) Treatment of cancer with cryochemotherapy. Br J Cancer 86: 1658-1660
19. Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, Yamashita T, Tokino T, Taniguchi T, Tanaka N (2000) Noxa, a BH3-only member of the bcl-2 family and candidate mediator of p53-induced apoptosis. Science 288: 1053-1058
20. Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29: 2002-2007
21. Schmitt CA (2007) Cellular senescence and cancer treatment. Biochim Biophys Acta 1775: 5-20,
22. Vergnon JM (1999) Cryothérapie endobronchique: techniques et indications. Rev Mal Respir 16: 619-623
23. Willis SN, Fletcher JI, Kaufmann T, van Delft MF, Chen L, Czabotar PE, Ierino H, Lee EF, Fairlie WD, Bouillet P, Strasser A, Kluck RM, Adams JM, Huang DC (2007) Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak. Science 315: 856-859
24. Yang WL, Addona T, Nair DG, Qi L, Ravikumar TS (2003) Apoptosis induced by cryo-injury in human colorectal cancer cells is associated with mitochondrial dysfunction. Int J Cancer 103: 360-369
25. Yu J, Zhang L, Hwang PM, Kinzler KW, Vogelstein B (2001) Puma induces the rapid apoptosis of colorectal cancer cells. Mol Cell 7: 673-682