Embryonic lethality of fortilin-null mutant mice by BMP-pathway overactivation

Biochimica et Biophysica Acta - General Subjects

Volumn 1790, Issue 5, 2009, Pages 326-338

  Koide, Yuichi ^a   Kiyota, Tomomi ^b   Tonganunt, Moltira ^a,c   Pinkaew, Decha ^a,c,d   Liu, Zhihe ^a,d   Kato, Yoichi ^b   Hutadilok Towatana, Nongporn ^c   Phongdara, Amornrat ^c   Fujise, Ken ^a,d  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b FLORIDA STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c PRINCE OF SONGKLA UNIVERSITY   (Thailand)

^d University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Apoptosis; BMP; Fortilin; Knockout; Msx2; Targeted gene disruption

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; FORTILIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR MSX2; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLASTOCYST; CELL CULTURE; CELL GROWTH; CELL SURVIVAL; CONTROLLED STUDY; DNA FRAGMENTATION; EMBRYO; FEMALE; FIBROBLAST; GENE DISRUPTION; GENE FUNCTION; GENE OVEREXPRESSION; IN VIVO STUDY; INNER CELL MASS; LETHALITY; MALE; MOUSE; MOUSE MUTANT; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; TROPHOBLAST; WILD TYPE;

ANIMALS; APOPTOSIS; BETA-GALACTOSIDASE; BLASTOCYST; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEINS; CROSSES, GENETIC; EMBRYO LOSS; EMBRYO, MAMMALIAN; FERTILITY; FIBROBLASTS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEALTH; HUMANS; MICE; MICE, MUTANT STRAINS; NEURONS; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; TUMOR MARKERS, BIOLOGICAL; XENOPUS;

MAMMALIA; MUS;

EID: 67349139585     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2009.01.012     Document Type: Article

References (54)

1. Chitpatima S.T., Makrides S., Bandyopadhyay R., and Brawerman G. Nucleotide sequence of a major messenger RNA for a 21 kiloDalton polypeptide that is under translational control in mouse tumor cells. Nucleic Acids Res. 16 (1988) 2350
2. Gross B., Gaestel M., Bohm H., and Bielka H. cDNA sequence coding for a translationally controlled human tumor protein. Nucleic Acids Res. 17 (1989) 8367
3. Fujise K., Zhang D., Liu J., and Yeh E. Regulation of Apoptosis and Cell Cycle Progression by MCL1. Differential role of proliferating cell nuclear antigen. J. Biol. Chem. 275 (2000) 39458-39465
4. Zhang D., Li F., Weidner D., Mnjoyan Z.H., and Fujise K. Physical and functional interaction between MCL1 and fortilin. The potential role of MCL1 as a fortilin chaperone. J. Biol. Chem. 277 (2002) 37430-37438
5. Kozopas K.M., Yang T., Buchan H.L., Zhou P., and Craig R.W. MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2. Proc. Natl. Acad. Sci. U. S. A. 90 (1993) 3516-3520
6. Reynolds J.E., Yang T., Qian L., Jenkinson J.D., Zhou P., Eastman A., and Craig R.W. Mcl-1, a member of the Bcl-2 family, delays apoptosis induced by c-Myc overexpression in Chinese hamster ovary cells. Cancer Res. 54 (1994) 6348-6352
7. Reynolds J.E., Li J., Craig R.W., and Eastman A. BCL-2 and MCL-1 expression in Chinese hamster ovary cells inhibits intracellular acidification and apoptosis induced by staurosporine. Exp. Cell Res. 225 (1996) 430-436
8. Tuynder M., Susini L., Prieur S., Besse S., Fiucci G., Amson R., and Telerman A. Biological models and genes of tumor reversion: cellular reprogramming through tpt1/TCTP and SIAH-1. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 14976-14981
9. F. Li, D. Zhang, K. Fujise, Characterization of fortilin, a novel anti-apoptotic protein, J. Biol. Chem. 276 (2001) 47542-47549.
10. Liu H., Peng H.W., Cheng Y.S., Yuan H.S., and Yang-Yen H.F. Stabilization and enhancement of the antiapoptotic activity of mcl-1 by TCTP. Mol. Cell. Biol. 25 (2005) 3117-3126
11. Graidist P., Phongdara A., and Fujise K. Antiapoptotic protein partners fortilin and MCL1 independently protect cells from 5-FU-induced cytotoxicity. J. Biol. Chem. 279 (2004) 40868-40875
12. Lazebnik Y.A., Kaufmann S.H., Desnoyers S., Poirier G.G., and Earnshaw W.C. Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 371 (1994) 346-347
13. Tewari M., Quan L.T., O'Rourke K., Desnoyers S., Zeng Z., Beidler D.R., Poirier G.G., Salvesen G.S., and Dixit V.M. Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 81 (1995) 801-809
14. Lee J.H., Rho S.B., Park S.Y., and Chun T. Interaction between fortilin and transforming growth factor-beta stimulated clone-22 (TSC-22) prevents apoptosis via the destabilization of TSC-22. FEBS Lett. 582 (2008) 1210-1218
15. Heid C.A., Stevens J., Livak K.J., and Williams P.M. Real time quantitative PCR. Genome Res. 6 (1996) 986-994
16. Gibson U.E., Heid C.A., and Williams P.M. A novel method for real time quantitative RT-PCR. Genome Res. 6 (1996) 995-1001
17. Chomczynski P., and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162 (1987) 156-159
18. Nieuwkoop P.D., and Faber J. Normal Table of Xenopus laevis (Daudin) (1994), Garland Publishing, New York
19. Harland R.M. In situ hybridization: an improved whole-mount method for Xenopus embryos. Methods Cell Biol. 36 (1991) 685-695
20. Cho K.W., Blumberg B., Steinbeisser H., and De Robertis E.M. Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid. Cell 67 (1991) 1111-1120
21. Smith W.C., McKendry R., Ribisi Jr. S., and Harland R.M. A nodal-related gene defines a physical and functional domain within the Spemann organizer. Cell 82 (1995) 37-46
22. Kao K.R., and Elinson R.P. The entire mesodermal mantle behaves as Spemann's organizer in dorsoanterior enhanced Xenopus laevis embryos. Dev. Biol. 127 (1988) 64-77
23. Graham A., Francis-West P., Brickell P., and Lumsden A. The signalling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest. Nature 372 (1994) 684-686
24. Gomes W.A., and Kessler J.A. Msx2 and p21 mediate the pro-apoptotic but not the anti-proliferative effects of BMP4 on cultured sympathetic neuroblasts. Dev. Biol. 237 (2001) 212-221
25. Furuta Y., Piston D.W., and Hogan B.L. Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development. Development 124 (1997) 2203-2212
26. Ferrari D., Lichtler A.C., Pan Z.Z., Dealy C.N., Upholt W.B., and Kosher R.A. Ectopic expression of Msx2 in posterior limb bud mesoderm impairs limb morphogenesis while inducing BMP-4 expression, inhibiting cell proliferation, and promoting apoptosis. Dev. Biol. 197 (1998) 12-24
27. Bachiller D., Klingensmith J., Kemp C., Belo J.A., Anderson R.M., May S.R., McMahon J.A., McMahon A.P., Harland R.M., Rossant J., and De Robertis E.M. The organizer factors Chordin and Noggin are required for mouse forebrain development. Nature 403 (2000) 658-661
28. Cao X., and Chen D. The BMP signaling and in vivo bone formation. Gene 357 (2005) 1-8
29. Marazzi G., Wang Y., and Sassoon D. Msx2 is a transcriptional regulator in the BMP4-mediated programmed cell death pathway. Dev. Biol. 186 (1997) 127-138
30. Panchision D.M., Pickel J.M., Studer L., Lee S.H., Turner P.A., Hazel T.G., and McKay R.D. Sequential actions of BMP receptors control neural precursor cell production and fate. Genes Dev. 15 (2001) 2094-2110
31. Hawley S.H., Wunnenberg-Stapleton K., Hashimoto C., Laurent M.N., Watabe T., Blumberg B.W., and Cho K.W. Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction. Genes Dev. 9 (1995) 2923-2935
32. Ying Q.L., Nichols J., Chambers I., and Smith A. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 115 (2003) 281-292
33. Chambers I., and Smith A. Self-renewal of teratocarcinoma and embryonic stem cells. Oncogene 23 (2004) 7150-7160
34. Kingsley D.M. The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev. 8 (1994) 133-146
35. Langman J. Medical Embryology. 4th ed (1980), Williams & Wilkins, Baltimore/London
36. Wilson P.A., and Hemmati-Brivanlou A. Induction of epidermis and inhibition of neural fate by Bmp-4. Nature 376 (1995) 331-333
37. Winnier G., Blessing M., Labosky P.A., and Hogan B.L. Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev. 9 (1995) 2105-2116
38. De Robertis E.M., and Kuroda H. Dorsal-ventral patterning and neural induction in Xenopus embryos. Annu. Rev. Cell Dev. Biol. 20 (2004) 285-308
39. Fainsod A., Steinbeisser H., and De Robertis E.M. On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo. EMBO J. 13 (1994) 5015-5025
40. Hemmati-Brivanlou A., and Thomsen G.H. Ventral mesodermal patterning in Xenopus embryos: expression patterns and activities of BMP-2 and BMP-4. Dev. Genet. 17 (1995) 78-89
41. Zimmerman L.B., De Jesus-Escobar J.M., and Harland R.M. The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell 86 (1996) 599-606
42. Piccolo S., Sasai Y., Lu B., and De Robertis E.M. Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4. Cell 86 (1996) 589-598
43. Sasai Y., Lu B., Steinbeisser H., Geissert D., Gont L.K., and De Robertis E.M. Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79 (1994) 779-790
44. Smith W.C., and Harland R.M. Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos. Cell 70 (1992) 829-840
45. McMahon J.A., Takada S., Zimmerman L.B., Fan C.M., Harland R.M., and McMahon A.P. Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite. Genes Dev. 12 (1998) 1438-1452
46. Jones C.M., Kuehn M.R., Hogan B.L., Smith J.C., and Wright C.V. Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation. Development 121 (1995) 3651-3662
47. McMahon A.P., and Moon R.T. Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis. Cell 58 (1989) 1075-1084
48. Watabe T., Kim S., Candia A., Rothbacher U., Hashimoto C., Inoue K., and Cho K.W. Molecular mechanisms of Spemann's organizer formation: conserved growth factor synergy between Xenopus and mouse. Genes Dev. 9 (1995) 3038-3050
49. McKendry R., Hsu S.C., Harland R.M., and Grosschedl R. LEF-1/TCF proteins mediate wnt-inducible transcription from the Xenopus nodal-related 3 promoter. Dev. Biol. 192 (1997) 420-431
50. Chen S.H., Wu P.S., Chou C.H., Yan Y.T., Liu H., Weng S.Y., and Yang-Yen H.F. A knockout mouse approach reveals that TCTP functions as an essential factor for cell proliferation and survival in a tissue- or cell type-specific manner. Mol. Biol. Cell 18 (2007) 2525-2532
51. Graidist P., Yazawa M., Tonganunt M., Nakatomi A., Lin C., Phongdara A., and Fujise K. Fortilin binds Ca2+ and blocks Ca2+-dependent apoptosis in vivo. Biochem. J. 408 (2007) 181-191
52. Hsu Y.C., Chern J.J., Cai Y., Liu M., and Choi K.W. Drosophila TCTP is essential for growth and proliferation through regulation of dRheb GTPase. Nature 445 (2007) 785-788
53. Stocker H., Radimerski T., Schindelholz B., Wittwer F., Belawat P., Daram P., Breuer S., Thomas G., and Hafen E. Rheb is an essential regulator of S6K in controlling cell growth in Drosophila. Nat. Cell Biol. 5 (2003) 559-565
54. Kawasome H., Papst P., Webb S., Keller G.M., Johnson G.L., Gelfand E.W., and Terada N. Targeted disruption of p70(s6 k) defines its role in protein synthesis and rapamycin sensitivity. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 5033-5038