An oncogenic role for the multiple endocrine neoplasia type 1 gene in prostate cancer

Prostate Cancer and Prostatic Diseases

Volumn 12, Issue 2, 2009, Pages 184-191

  Paris, P L ^a   Sridharan, S ^a   Hittelman, A B ^a   Kobayashi, Y ^a   Perner, S ^b   Huang, G ^a   Simko, J ^c   Carroll, P ^a   Rubin, M A ^b   Collins, C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SMALL INTERFERING RNA;

ARTICLE; CANCER GROWTH; CARCINOGENESIS; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION; GENE FUNCTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; METASTASIS; MULTIPLE ENDOCRINE NEOPLASIA; PRIORITY JOURNAL; PROSTATE CANCER; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE MICROARRAY;

CELL LINE, TUMOR; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; TISSUE ARRAY ANALYSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 67349138523     PISSN: 13657852     EISSN: 14765608     Source Type: Journal    
DOI: 10.1038/pcan.2008.45     Document Type: Article

References (34)

1. Chandrasekharappa SC, Teh BT. Functional studies of the MEN1 gene. J Intern Med 2003; 253: 606-615.
2. Pannett AA, Thakker RV. Multiple endocrine neoplasia type 1. Endocr Relat Cancer 1999; 6: 449-473.
3. Guru SC, Manickam P, Crabtree JS, Olufemi SE, Agarwal SK, Debelenko LV. Identification and characterization of the multiple endocrine neoplasia type 1 (MEN1) gene. J Intern Med 1998; 243: 433-439.
4. Lemos MC, Thakker RV. Multiple endocrine neoplasia type 1 (MEN1): analysis of 1336 mutations reported in the first decade following identification of the gene. Hum Mutat 2008; 29: 22-32.
5. Larsson C, Skogseid B, Oberg K, Nakamura Y, Nordenskjold M. Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma. Nature 1988; 332: 85-87.
6. Hughes CM, Rozenblatt-Rosen O, Milne TA, Copeland TD, Levine SS, Lee JC et al. Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus. Mol Cell 2004; 13: 587-597.
7. Yokoyama A, Wang Z, Wysocka J, Sanyal M, Aufiero DJ, Kitabayashi I et al. Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression. Mol Cell Biol 2004; 24: 5639-5649.
8. Schussheim DH, Skarulis MC, Agarwal SK, Simonds WF, Burns AL, Spiegel AM et al. Multiple endocrine neoplasia type 1: New clinical and basic findings. Trends Endocrinol Metab 2001; 12: 173-178.
9. Trump D, Farren B, Wooding C, Pang JT, Besser GM, Buchanan KD et al Clinical studies of multiple endocrine neoplasia type 1 (MEN1). QJM 1996; 89: 653-669.
10. Paris PL, Andaya A, Fridlyand J, Jain AN, Weinberg V, Kowbel D et al Whole genome scanning identifies genotypes associated with recurrence and metastasis in prostate tumors. Hum Mol Genet 2004; 13: 1303-1313.
11. Lapointe J, Li C, Higgins JP, van de Rijn M, Bair E, Montgomery K et al. Gene expression profiling identifies clinically relevant subtypes of prostate cancer. Proc Natl Acad Sci USA 2004; 101: 811-816.
12. Perner S, Wagner PL, Demichelis F, Mehra R, Lafargue CJ, Moss BJ et al. EML4-ALK fusion lung cancer: A rare acquired event. Neoplasia 2008; 10: 298-302.
13. Rubin MA, Putzi M, Mucci N, Smith DC, Wojno K, Korenchuk S et al. Rapid ('warm') autopsy study for procurement of metastatic prostate cancer. Clin Cancer Res 2000; 6: 1038-1045.
14. Bolstad BM, Irizarry RA, Astrand M, Speed TP. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 2003; 19: 185-193.
15. Thomas PD, Campbell MJ, Kejariwal A, Mi H, Karlak B, Daverman R et al PANTHER: A library of protein families and subfamilies indexed by function. Genome Res 2003; 13: 2129-2141.
16. Thomas PD, Kejariwal A, Guo N, Mi H, Campbell MJ, Muruganujan A et al Applications for protein sequence-function evolution data: MRNA/ protein expression analysis and coding SNP scoring tools. Nucleic Acids Res 2006; 34: W645-W650.
17. Kattan MW, Wheeler TM, Scardino PT. Postoperative nomogram for disease recurrence after radical prostatectomy for prostate cancer. J Clin Oncol 1999; 17: 1499-1507.
18. Dhanasekaran SM, Barrette TR, Ghosh D, Shah R, Varambally S, Kurachi K et al. Delineation of prognostic biomarkers in prostate cancer. Nature 2001; 412: 822-826.
19. Dhanasekaran SM, Dash A, Yu J, Maine IP, Laxman B, Tomlins SA et al Molecular profiling of human prostate tissues: Insights into gene expression patterns of prostate development during puberty. FASEB J 2005; 19: 243-245.
20. Tomlins SA, Mehra R, Rhodes DR, Cao X, Wang L, Dhanasekaran SM et al Integrative molecular concept modeling of prostate cancer progression. Nat Genet 2007; 39: 41-51.
21. Vanaja DK, Cheville JC, Iturria SJ, Young CY. Transcriptional silencing of zinc finger protein 185 identified by expression profiling is associated with prostate cancer progression. Cancer Res 2003; 63: 3877-3882.
22. Varambally S, Yu J, Laxman B, Rhodes DR, Mehra R, Tomlins SA et al Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression. Cancer Cell 2005; 8: 393-406.
23. Schnepp RW, Mao H, Sykes SM, Zong WX, Silva A, La P et al. Menin induces apoptosis in murine embryonic fibroblasts. J Biol Chem 2004; 279: 10685-10691.
24. Guru SC, Goldsmith PK, Burns AL, Marx SJ, Spiegel AM, Collins FS et al. Menin, the product of the MEN1 gene, is a nuclear protein. Proc Natl Acad Sci USA 1998; 95: 1630-1634.
25. La P, Desmond A, Hou Z, Silva AC, Schnepp RW, Hua X. Tumor suppressor menin: The essential role of nuclear localization signal domains in coordinating gene expression. Oncogene 2006; 25: 3537-3546.
26. Jensen RT. Management of the Zollinger-Ellison syndrome in patients with multiple endocrine neoplasia type 1. J Intern Med 1998; 243: 477-488.
27. Norton JA, Fraker DL, Alexander HR, Venzon DJ, Doppman JL, Serrano J et al. Surgery to cure the Zollinger-Ellison syndrome. N Engl J Med 1999; 341: 635-644.
28. Weber HC, Venzon DJ, Lin JT, Fishbein VA, Orbuch M, Strader DB et al Determinants of metastatic rate and survival in patients with Zollinger-Ellison syndrome: A prospective long-term study. Gastroenterology 1995; 108: 1637-1649.
29. Milne TA, Hughes CM, Lloyd R, Yang Z, Rozenblatt-Rosen O, Dou Y et al Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors. Proc Natl Acad Sci USA 2005; 102: 749-754.
30. Agarwal SK, Guru SC, Heppner C, Erdos MR, Collins RM, Park SY et al Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription. Cell 1999; 96: 143-152.
31. Yokoyama A, Somervaille TC, Smith KS, Rozenblatt-Rosen O, Meyerson M, Cleary ML. The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis. Cell 2005; 123: 207-218.
32. Karnik SK, Chen H, McLean GW, Heit JJ, Gu X, Zhang AY et al. Menin controls growth of pancreatic beta-cells in pregnant mice and promotes gestational diabetes mellitus. Science 2007; 318: 806-809.
33. Luo J, Duggan DJ, Chen Y, Sauvageot J, Ewing CM, Bittner ML et al. Human prostate cancer and benign prostatic hyperplasia: Molecular dissection by gene expression profiling. Cancer Res 2001; 61 4683-4688.
34. Snijders AM, Nowak N, Segraves R, Blackwood S, Brown N, Conroy J et al. Assembly of microarrays for genome-wide measurement of DNA copy number. Nat Genet 2001; 29: 263-264.