The relation between neurocognitive dysfunction and impaired insight in patients with schizophrenia

European Psychiatry

Volumn 24, Issue 4, 2009, Pages 239-243

  Simon, Viktoria ^a   De Hert, Marc ^b   Wampers, Martien ^b   Peuskens, Joseph ^b   van Winkel, Ruud ^b,c  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^c Department of Psychiatry and Psychology   (Netherlands)

Author keywords

Executive functions; Insight; Schizophrenia; Working memory

Indexed keywords

ADULT; ARTICLE; AWARENESS; AWARENESS OF HAVING A MENTAL ILLNESS; AWARENESS OF HAVING SYMPTOMS ATTRIBUTED TO A MENTAL ILLNESS; BRAIN FUNCTION; CLINICAL EVALUATION; COGNITIVE DEFECT; DISEASE ASSOCIATION; FEMALE; HUMAN; LETTER NUMBER SEQUENCING; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PSYCHOLOGIC TEST; PSYCHOSIS EVALUATION TOOL FOR COMMON USE BY CAREGIVER; SCHIZOPHRENIA; SCORING SYSTEM; SEMI STRUCTURED INTERVIEW; SYMPTOM; SYMPTOMATOLOGY; WECHSLER INTELLIGENCE SCALE; WISCONSIN CARD SORTING TEST; WORKING MEMORY;

ADULT; AWARENESS; COGNITION DISORDERS; FEMALE; FRONTAL LOBE; HEALTH STATUS; HUMANS; MALE; MEMORY DISORDERS; NEUROPSYCHOLOGICAL TESTS; PSYCHIATRIC STATUS RATING SCALES; PSYCHOMETRICS; QUESTIONNAIRES; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; SEVERITY OF ILLNESS INDEX; WECHSLER SCALES;

EID: 67349137034     PISSN: 09249338     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eurpsy.2008.10.004     Document Type: Article

References (35)

1. Aleman A., Agrawal N., Morgan K.D., and David A.S. Insight in psychosis and neuropsychological function: meta-analysis. Br J Psychiatry 189 (2006) 204-212
2. Aleman A., de Haan E.H., and Kahn R.S. Insight and neurocognitive function in schizophrenia. J Neuropsychiatry Clin Neurosci 14 2 (2002) 241-242
3. Amador X., and David A. Insight and psychosis (1998), Oxford University Press, New York
4. Amador X.F., Flaum M., Andreasen N.C., Strauss D.H., Yale S.A., Clark S.C., et al. Awareness of illness in schizophrenia and schizoaffective and mood disorders. Arch Gen Psychiatry 51 10 (1994) 826-836
5. Amador X.F., and Gorman J.M. Psychopathologic domains and insight in schizophrenia. Psychiatr Clin North Am 21 1 (1998) 27-42
6. Bora E., Sehitoglu G., Aslier M., Atabay I., and Veznedaroglu B. Theory of mind and unawareness of illness in schizophrenia: is poor insight a mentalizing deficit?. Eur Arch Psychiatry Clin Neurosci 257 2 (2007) 104-111
7. Buckley P.F., Wirshing D.A., Bhushan P., Pierre J.M., Resnick S.A., and Wirshing W.C. Lack of insight in schizophrenia: impact on treatment adherence. CNS Drugs 21 2 (2007) 129-141
8. Carroll A., Fattah S., Clyde Z., Coffey I., Owens D.G., and Johnstone E.C. Correlates of insight and insight change in schizophrenia. Schizophr Res 35 3 (1999) 247-253
9. Collins A.A., Remington G.J., Coulter K., and Birkett K. Insight, neurocognitive function and symptom clusters in chronic schizophrenia. Schizophr Res 27 1 (1997) 37-44
10. De Hert M., van Winkel R., Wampers M., Kane J., van Os J., and Peuskens J. Remission criteria for schizophrenia: evaluation in a large naturalistic cohort. Schizophr Res 92 1-3 (2007) 68-73
11. De Hert M., Wampers M., Thys E., Wieselgren I.M., Lindstrom E., and Peuskens J. Validation study of PECC (Psychosis Evaluation tool for Common use by Caregivers): interscale validity and inter-rater reliability. Int J Psych Clin Pract 6 (2002) 135-140
12. Drake R.J., and Lewis S.W. Insight and neurocognition in schizophrenia. Schizophr Res 62 1-2 (2003) 165-173
13. Freudenreich O., Deckersbach T., and Goff D.C. Insight into current symptoms of schizophrenia. Association with frontal cortical function and affect. Acta Psychiatr Scand 110 1 (2004) 14-20
14. Goldberg R.W., Green-Paden L.D., Lehman A.F., and Gold J.M. Correlates of insight in serious mental illness. J Nerv Ment Dis 189 3 (2001) 137-145
15. Goodman C., Knoll G., Isakov V., and Silver H. Insight into illness in schizophrenia. Compr Psychiatry 46 4 (2005) 284-290
16. Heaton R. Wisconsin card sort test manual (1981), Psychological Assessment Resources, Odessa
17. Kemp R., and David A. Psychological predictors of insight and compliance in psychotic patients. Br J Psychiatry 169 4 (1996) 444-450
18. Keshavan M.S., Rabinowitz J., DeSmedt G., Harvey P.D., and Schooler N. Correlates of insight in first episode psychosis. Schizophr Res 70 2-3 (2004) 187-194
19. Koren D., Seidman L.J., Poyurovsky M., Goldsmith M., Viksman P., Zichel S., et al. The neuropsychological basis of insight in first-episode schizophrenia: a pilot metacognitive study. Schizophr Res 70 2-3 (2004) 195-202
20. Lysaker P., and Bell M. Insight and cognitive impairment in schizophrenia. Performance on repeated administrations of the Wisconsin Card Sorting Test. J Nerv Ment Dis 182 11 (1994) 656-660
21. Lysaker P., and Bell M. Work rehabilitation and improvements in insight in schizophrenia. J Nerv Ment Dis 183 2 (1995) 103-106
22. Lysaker P.H., Bell M.D., Bryson G., and Kaplan E. Neurocognitive function and insight in schizophrenia: support for an association with impairments in executive function but not with impairments in global function. Acta Psychiatr Scand 97 4 (1998) 297-301
23. Lysaker P.H., Carcione A., Dimaggio G., Johannesen J.K., Nicolo G., Procacci M., et al. Metacognition amidst narratives of self and illness in schizophrenia: associations with neurocognition, symptoms, insight and quality of life. Acta Psychiatr Scand 112 1 (2005) 64-71
24. Lysaker P.H., Daroyanni P., Ringer J.M., Beattie N.L., Strasburger A.M., and Davis L.W. Associations of awareness of illness in schizophrenia spectrum disorder with social cognition and cognitive perceptual organization. J Nerv Ment Dis 195 7 (2007) 618-621
25. McEvoy J.P., Hartman M., Gottlieb D., Godwin S., Apperson L.J., and Wilson W. Common sense, insight, and neuropsychological test performance in schizophrenia patients. Schizophr Bull 22 4 (1996) 635-641
26. Mintz A.R., Dobson K.S., and Romney D.M. Insight in schizophrenia: a meta-analysis. Schizophr Res 61 1 (2003) 75-88
27. Mutsatsa S.H., Joyce E.M., Hutton S.B., and Barnes T.R. Relationship between insight, cognitive function, social function and symptomatology in schizophrenia: the West London first episode study. Eur Arch Psychiatry Clin Neurosci 256 6 (2006) 356-363
28. Reitan R.M. Ward Halstead's contributions to neuropsychology and the Halstead-Reitan Neuropsychological Test Battery. J Clin Psychol 50 1 (1994) 47-70
29. Rossell S.L., Coakes J., Shapleske J., Woodruff P.W., and David A.S. Insight: its relationship with cognitive function, brain volume and symptoms in schizophrenia. Psychol Med 33 1 (2003) 111-119
30. Sapara A., Cooke M., Fannon D., Francis A., Buchanan R.W., Anilkumar A.P., et al. Prefrontal cortex and insight in schizophrenia: a volumetric MRI study. Schizophr Res 89 1-3 (2007) 22-34
31. Shad M.U., Muddasani S., Prasad K., Sweeney J.A., and Keshavan M.S. Insight and prefrontal cortex in first-episode Schizophrenia. Neuroimage 22 3 (2004) 1315-1320
32. Simon V., De Hert M., Wampers M., Peuskens J., and van Winkel R. An 18-month prospective study of associations between insight and symptoms in a large sample of patients with schizophrenia. Schizophr Res 102 S2 (2008) 228
33. Smith T.E., Hull J.W., Israel L.M., and Willson D.F. Insight, symptoms, and neurocognition in schizophrenia and schizoaffective disorder. Schizophr Bull 26 1 (2000) 193-200
34. Wechsler D. Wechsler adult intelligence scale - revised (1981), The Psychological Corporation, New York
35. Young D.A., Davila R., and Scher H. Unawareness of illness and neuropsychological performance in chronic schizophrenia. Schizophr Res 10 2 (1993) 117-124