Insight into current symptoms of schizophrenia. Association with frontal cortical function and affect

Acta Psychiatrica Scandinavica

Volumn 110, Issue 1, 2004, Pages 14-20

  Freudenreich, O ^a,b   Deckersbacti, T ^a   Goff, D C ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Freedom Trail Clinic   (United States)

Author keywords

Dysphoria; Frontal lobe dysfunction; Lack of insight; Schizophrenia; Symptom unawareness

Indexed keywords

ADULT; AFFECT; AGED; ANXIETY; ARTICLE; AWARENESS; BRAIN DYSFUNCTION; BRAIN FUNCTION; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; EXPERIENCE; FEMALE; FRONTAL CORTEX; FRONTAL LOBE; HUMAN; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; MENTAL PATIENT; NEUROPSYCHOLOGICAL TEST; OUTPATIENT; PRIORITY JOURNAL; RATING SCALE; SCHIZOPHRENIA; SENSITIVITY ANALYSIS; STANDARD; SYMPTOM;

ADULT; AFFECT; AGED; COHORT STUDIES; CROSS-SECTIONAL STUDIES; FEMALE; FRONTAL LOBE; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; OUTPATIENTS; SCHIZOPHRENIA; SELF PSYCHOLOGY;

EID: 3042654750     PISSN: 0001690X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0447.2004.00319.x     Document Type: Article

References (47)

1. LEWIS A. The psychopathology of insight. Br J Med Psychol 1934;14:332-348.
2. CARPENTER WT, Jr, STRAUSS JS, BARTKO JJ. Flexible system for the diagnosis of schizophrenia: report from the WHO international pilot study of schizophrenia. Science 1973;182:1275-1278.
3. AMADOR XF, STRAUSS DH, YALE SA, GORMAN JM. Awareness of illness in schizophrenia. Schizophr Bull 1991;17:113-132.
4. DAVID A, KEMP R. Five perspectives on the phenomenon of insight in psychosis. Psychiatr Ann 1997;27:791-797.
5. MCEVOY JP, ALAND J, Jr, WILSON WH, GUY W, HAWKINS L. Measuring chronic schizophrenic patients' attitudes toward their illness and treatment. Hosp Community Psychiatry 1981;32:856-858.
6. AMADOR XF, STRAUSS DH, YALE SA, FLAUM MM, ENDICOTT J, GORMAN JM. Assessment of insight in psychosis. Am J Psychiatry 1993;150:873-879.
7. CUESTA MJ, PERALTA V. Lack of insight in schizophrenia. Schizophr Bull 1994;20:359-366.
8. YOUNG DA, DAVILA R, SCHER H. Unawareness of illness and neuropsychological performance in chronic schizophrenia. Schizophr Res 1993;10:117-124.
9. LYSAKER P, BELL M. Insight and cognitive impairment in schizophrenia. Performance on repeated administration of the Wisconsin Card Sort Test. J Nerv Ment Dis 1994;182:656-660.
10. YOUNG DA, ZAKZANIS KK, BAILEY C et al. Further parameters of insight and neuropsychological deficit in schizophrenia and other chronic mental disease. J Nerv Ment Dis 1998;186:44-50.
11. MOHAMED S, FLEMING S, PENN DL, SPAULDING W. Insight in schizophrenia: its relationship to measures of executive functions. J Nerv Ment Dis 1999;187:525-531.
12. MCEVOY JP, FRETER S, MERRITT M, APPERSON LJ. Insight about psychosis among outpatients with schizophrenia. Hosp Community Psychiatry 1993;44:883-884.
13. CUESTA MJ, PERALTA V, CARO F, DE LEON J. Is poor insight in psychotic disorders associated with poor performance on the Wisconsin card sorting test? Am J Psychiatry 1995;152:1380-1382.
14. KEMP R, DAVID A. Psychological predictors of insight and compliance in psychotic patients. Br J Psychiatry 1996;169:444-450.
15. ALEMAN A, DE HAAN EHF, KAHN RS. Insight and neurocongitive function in schizophrenia (letter). J Neuropsychiatry Clin Neurosci 2002;14:241-242.
16. MCCABE R, QUAYLE E, BEIRNE AD, ANNE DUANE MM. Insight, global neuropsychological functioning, and symptomatology in chronic schizophrenia. J Nerv Ment Dis 2002;190:519-525.
17. ARDUINI L, KALYVOKA A, STRATTA P, RINALDI O, DANELUZZO E, ROSSI A. Insight and neuropsychological function in patients with schizophrenia and bipolar disorder with psychotic features. Can J Psychiatry 2003;48:338-341.
18. GHAEMI SN, STOLL AL, POPE HG, Jr. Lack of insight in bipolar disorder. The acute manic episode. J Nerv Ment Dis 1995;183:464-467.
19. MICHALAKEAS A, SKOUTAS C, CHARALAMBOUS A et al. Insight in schizophrenia and mood disorders and its relation to psychopathology. Acta Psychiatr Scand 1994;90:46-49.
20. SMITH TE, HULL JW, ISRAEL LM, WILLSON DF. Insight, symptoms, and neurocognition in schizophrenia and schizoaffective disorder. Schizophr Bull 2000;26:193-200.
21. AMADOR XF, FLAUM M, ANDREASEN NC et al. Awareness of illness in schizophrenia and schizoaffective and mood disorders. Arch Gen Psychiatry 1994;51:826-836.
22. JOHNSON S, ORRELL M. Insight and psychosis: a social perspective. Psychol Med 1995;25:515-520.
23. JOHNSON S, ORRELL M. Insight, psychosis and ethnicity: a case-note study. Psychol Med 1996;26:1081-1084.
24. MARKOVA IS, BERRIOS GE. Insight in clinical psychiatry. A clinical model. J Nerv Ment Dis 1995;183:743-751.
25. KAY SR, FISZBEIN A, OPLER LA. The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophr Bull 1987;13:261-276.
26. HAMILTON M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960;23:56-62.
27. WECHSLER D. Wechsler adult intelligence scale, 3rd edn (WAIS-III). San Antonio, TX: The Psychological Corporation, 1997.
28. DELIS DC, KRAMER JH, KAPLAN E, OBER BA. California verbal learning test research edition manual adult version. San Antonio, TX: The Psychological Corporation, 1987.
29. HEATON RK. Wisconsin card sorting test manual. Odessa, TX: Psychological Assessment Resources, 1981.
30. STROOP JR. Studies of interference in serial verbal reactions. J Exp Psychol 1935;18:643-662.
31. BENTON AL. Differential behavioral effects in frontal lobe disease. Neuropsychologia 1968;6:53-60.
32. BENTON AL, HAMSHER KD. Multilingual aphasia examination. Iowa City, IA: AJA Associates, 1989.
33. MCEVOY JP, HARTMAN M, GOTTLIEB D, GODWIN S, APPERSON LJ, WILSON W. Common sense, insight, and neuropsychological test performance in schizophrenia patients. Schizophr Bull 1996;22:635-641.
34. COLLINS AA, REMINGTON GJ, COULTER K, BIRKETT K. Insight, neurocognitive function and symptom clusters in chronic schizophrenia. Schizophr Res 1997;27:37-44.
35. DIXON M, KING S, STEIGER H. The contribution of depression and denial towards understanding the unawareness of symptoms in schizophrenic out-patients. Br J Med Psychol 1998;71:85-97.
36. MOORE O, CASSIDY E, CARR A, O'CALLAGHAN E. Unawareness of illness and its relationship with depression and self-deception in schizophrenia. Eur Psychiatry 1999;14:264-269.
37. SMITH TE, HULL JW, GOODMAN M et al. The relative influences of symptoms, insight, and neurocognition on social adjustment in schizophrenia and schizoaffective disorder. J Nerv Ment Dis 1999;187:102-108.
38. CUESTA MJ, PERALTA V, ZARZUELA A. Reappraising insight in psychosis. Multi-scale longitudinal study. Br J Psychiatry 2000;177:233-240.
39. AMADOR XF, FRIEDMAN JH, KASAPIS C, YALE SA, FLAUM M, GORMAN JM. Suicidal behavior in schizophrenia and its relationship to awareness of illness. Am J Psychiatry 1996;153:1185-1188.
40. HUPPERT JD, SMITH TE. Longitudinal analysis of subjective quality of life in schizophrenia: anxiety as the best symptom predictor. J Nerv Ment Dis 2001;189:669-675.
41. HUPPERT JD, WEISS KA, LIM R, PRATT S, SMITH TE. Quality of life in schizophrenia: contributions of anxiety and depression. Schizophr Res 2001;51:171-180.
42. YOUNG AS, SULLIVAN G, BURNAM A, BROOK RH. Measuring the quality of outpatient treatment for schizophrenia. Arch Gen Psychiatry 1998;55:611-617.
43. MCKENNA PJ, TAMLYN D, LUND CE, MORTIMER AM, HAMMOND S, BADDELEY AD. Amnesic syndrome in schizophrenia. Psychol Med 1990;20:967-972.
44. ANGERMEYER MC, KLUSMANN D. The causes of functional psychoses as seen by patients and their relatives. I. The patients' point of view. Eur Arch Psychiatry Neurol Sci 1988;238:47-54.
45. JOEL D, SATHYASEELAN M, JAYAKARAN R, VIJAYAKUMAR C, MUTHURATHNAM S, JACOB KS. Explanatory models of psychosis among community health workers in South India. Acta Psychiatr Scand 2003;108:66-69.
46. MECHANIC D, MCALPINE D, ROSENFIELD S, DAVIS D. Effects of illness attribution and depression on the quality of life among persons with serious mental illness. Soc Sci Med 1994;39:155-164.
47. MUTSATSA SH, JOYCE EM, HUTTON SB et al. Clinical correlates of early medication adherence: West London first episode schizophrenia study. Acta Psychiatr Scand 2003;108:439-446.