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Volumn 20, Issue 6, 2009, Pages 680-683

Synthesis and biological evaluation of novel steroid-linked nitrogen mustards

Author keywords

Biological activity; Nitrogen mustards; Steroid; Synthesis

Indexed keywords


EID: 67349126885     PISSN: 10018417     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cclet.2009.01.023     Document Type: Article
Times cited : (13)

References (17)
  • 9
    • 67349200760 scopus 로고    scopus 로고
    • Special data of 1a: m.p, 83-84 °C 1H NMR (300 MHz, CDCl3, δ ppm, 7.48 (s, 1H, PhOH, 7.37 (d, 1H, J, 8.7 Hz, PhH, 7.22 (d, 2H, J, 8.7 Hz, PhH, 6.86 (m, 3H, PhH, 6.79 (s, 1H, PhH, 5.02 (s, 2H, OCH2, 3.93 (t, 4H, J, 6.8 Hz, ClCH2, 3.83 (t, 4H, J, 6.8 Hz, NCH2, 13C NMR (75 MHz, CDCl3, δ ppm, 173.0, 169.8, 153.6, 144.0, 141.7, 137.9, 132.1, 126.4, 122.4, 115.2, 112.7, 112.4, 70.1, 53.7, 52.7, 44.5, 43.8, 40.3, 38.0, 34.0, 29.5, 27.1, 26.1, 23.0, 17.1; HRMS (ESI) calcd. for C30H36Cl2N2O4 C30H36Cl2N2O4, H, 559.2125, found 558.2126
    • +) 559.2125, found 558.2126.
  • 10
    • 67349181784 scopus 로고    scopus 로고
    • Special data of 1b: m.p.123-124 °C, 1H NMR (300 MHz, CDCl3, δ ppm, 7.49 (s, 1H, PhOH, 7.40 (d, 2H, J, 8.4 Hz, PhH, 7.13 (d, 1H, J, 8.1 Hz, PhH, 6.66 (m, 3H, PhH, 6.594 (s, 1H, PhH, 4.83 (s, 2H, OCH2, 3.70 (t, 4H, J, 6.8 Hz, ClCH2, 3.60 (t, 4H, J, 6.5 Hz, NCH2);13C NMR (75 MHz, CDCl3, δ ppm, 173.5, 168.7, 162.2, 143.4, 137.6, 127.4, 126.2, 122.4, 115.2, 112.9, 112.3, 72.5, 53.5, 52.8, 44.8, 44.5, 43.8, 40.3, 38.0, 34.0, 29.4, 27.2, 26.2, 22.9, 17.3; HRMS (ESI) calcd. for C30H37Cl2N3O3 C30H37Cl2N3O3+H, 558.2285, found 558.2280
    • +) 558.2285, found 558.2280.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.