The versatility of algae and their lipid metabolism

Biochimie

Volumn 91, Issue 6, 2009, Pages 679-684

  Harwood, John L ^a   Guschina, Irina A ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Biotechnology; Eukaryotic algae; Fatty acid synthesis; Lipids; Polyunsaturated fatty acids

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; GAMMA LINOLENIC ACID; ICOSAPENTAENOIC ACID; POLYUNSATURATED FATTY ACID;

ALGA; BIOMASS PRODUCTION; DRUG ACTIVITY; FATTY ACID ANALYSIS; HUMAN; LIPID COMPOSITION; LIPID METABOLISM; LIPOGENESIS; NONHUMAN; REVIEW;

ALGAE; BIOSYNTHETIC PATHWAYS; BIOTECHNOLOGY; FATTY ACID DESATURASES; FATTY ACIDS; FATTY ACIDS, UNSATURATED; LIPID METABOLISM; SPECIES SPECIFICITY;

ALGAE; EUKARYOTA;

EID: 67349118208     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2008.11.004     Document Type: Review

References (42)

1. Hitchcock C., and Nichols B.W. Plant Lipid Biochemistry (1971), Academic Press, London
2. Guschina I.A., and Harwood J.L. Lipids and lipid metabolism in eukaryotic algae. Prog. Lipid Res. 45 (2006) 160-186
3. Harwood J.L., Pettitt T.P., and Jones A.L. Lipid metabolism. In: Rogers L.J., and Gallon J.R. (Eds). Biochemistry of the Algae and Cyanobacteria (1988), Clarendon Press, Oxford 49-67
4. Harwood J.L., and Jones A.L. Lipid metabolism in algae. Adv. Bot. Res. 16 (1989) 1-53
5. Harwood J.L. Membrane lipids in algae. In: Siegenthaler P.-A., and Murata N. (Eds). Lipids in Photosynthesis: Structure, Function and Genetics (1998), Kluwer, Dordrecht 53-64
6. Eichenberger W. Identification of new plant lipids: structure of a second betaine lipid from algae. In: Quinn P.J., and Harwood J.L. (Eds). Plant Lipid Biochemistry, Structure and Utilisation (1990), Portland Press, London 9-16
7. Haines T. Sulpholipids and halosulpholipids. In: Erwin J.A. (Ed). Biomembranes of Eukaryotic Microorganisms (1973), Academic Press, New York 197-232
8. Dembitsky V.M., and Srebnik M. Natural halogenated fatty acids: their analogues and derivatives. Prog. Lipid. Res. 41 (2002) 315-367
9. Napier J.A. The production of unusual fatty acids in transgenic plants. Annu. Rev. Plant Biol. 58 (2007) 295-319
10. Qiu X., Hong H., and Mackenzie S.L. Identification of a Δ4 fatty acid desaturase from Thraustochytriun sp. involved in the biosynthesis of docosahexaenoic acid by heterologous expression in Saccharomyces cerevisiae and Brassica juncea. J. Biol. Chem. 34 (2001) 31561-31566
11. Metz J.G., Roessler P., Facciotti D., et al. Production of polyunsaturated fatty acids by polyketide synthases in both prokaryotes and eukaryotes. Science 293 (2001) 290-293
12. Harwood J.L. Recent advances in the biochemistry of plant fatty acids. Biochim. Biophys. Acta 1301 (1996) 7-56
13. Wallis J.G., and Browse J. Mutants of Arabidopsis reveal many roles for membrane lipids. Prog. Lipid Res. 41 (2002) 252-278
14. Sato N., and Moriyama T. Genomic and biochemical analysis of lipid biosynthesis in the unicellular rhodophyte Cyanidioschyzon merolae. Eukaryot. Cell 6 (2007) 1006-1017
15. Jones M.R. Lipids in photosynthetic reaction centres: structural roles and functional holes. Prog. Lipid Res. 46 (2007) 56-88
16. Sperling P., Ternes P., Zank T.K., and Heinz E. The evolution of desaturases. Prostaglandins Leukot. Essent. Fatty Acids 68 (2003) 73-95
17. Chi X., Zhang X., Guan X., et al. Fatty acid biosynthesis in eukaryotic photosynthetic microalgae: identification of a microsonal delta 12 desaturase in Chlamydomonas reinhardtii. J. Microbiol. 46 (2008) 189-201
18. Gurr M.I., Harwood J.L., and Frayn K.N. Lipid Biochemistry. fifth ed. (2002), Blackwells, Oxford
19. Colombo M.L., Rise P., Giavarini F., et al. Marine microalgae as sources of polyunsaturated fatty acids. Plant Foods Hum. Nutr. 61 (2006) 67-72
20. Pereira S.L., Leonard A.E., and Mukerji P. Recent advances in the study of fatty acid desaturases from animals and lower eukaryotes. Prostaglandins Leukot. Essent. Fatty Acids 68 (2003) 97-106
21. Leonard A.E., Pereira S.L., Sprecher H., and Huang Y.S. Elongation of long-chain fatty acids. Prog. Lipid Res. 43 (2004) 36-54
22. Tonon T., Harvey D., Larson T.R., and Graham I.A. Identification of a very long chain polyunsaturated fatty acid Δ4-desaturase from the microalga Pavlova lutheri. FEBS Lett. 553 (2003) 440-444
23. Hsiao T.Y., Holmes B., and Blanch H.W. Identification and functional analysis of a delta-6 desaturase from the marine microalga Glossomastix chrysoplasta. Mar Biotechnol. 9 (2007) 154-165
24. Pereira S.L., Leonard A.E., Huang Y.S., Chuang L.T., and Mukerji P. Identification of two novel microalgal enzymes involved in the conversion of the ω-3-fatty acid, eicosapentaenoic acid, into docosahexaenoic acid. Biochem. J. 384 (2004) 357-366
25. Zhou X.-R., Robert S.S., Petrie J.R., et al. Isolation and characterisation of genes from the marine microalga Pavlova saliva encoding three front-end desaturases involved in docosahexaenoic acid synthesis. Phytochemistry 68 (2007) 785-796
26. Kajikawa M., Yamato K.T., Kohzu Y., et al. A front-end desaturase from Chlamydomonas reinhardtii produces pinolenic and coniferonic acids by ω13 desaturation in methylotrophic yeast and tobacco. Plant Cell Physiol. 47 (2006) 64-73
27. 14C] oleate into different lipids and evidence for lipid-linked desaturation of fatty acids. Plant Cell Physiol. 30 (1989) 121-128
28. Spolaore P., Joannis-Cassan C., Duran E., and Isambert A. Commercial applications of microalgae. J. Biosci. Bioeng. 101 (2006) 87-96
29. Raja R., Hemaiswarya S., Askok Kumar N., Sridhas S., and Rengasamy R. A perspective on the biotechnological potential of microalgae. Crit. Rev. Microbiol. 34 (2008) 77-88
30. Hu Q., Sommerfeld M., Jarvis E., et al. Microalgal triacylglycerols as feedstocks for biofuel production: perspectives and advances. Plant J. 54 (2008) 621-639
31. Rittmann B.E. Opportunities for renewable bioenergy using microorganisms. Biotechnol. Bioeng. 100 (2008) 203-212
32. Ratledge C., and Cohen Z. Microbial and algal lipids: do they have a future for biodiesel or as commodity oils?. Lipid Technol. 20 (2008) 155-160
33. Harwood J.L., and Caterson B. Dietary omega-3 polyunsaturated fatty acids and inflammation. Lipid Technol. 18 (2006) 7-10
34. Cunnane S.C. Problems with essential fatty acids: time for a new paradigm?. Prog. Lipid Res. 42 (2003) 544-568
35. Morris M.C., Evans D.A., Bienias J.L., et al. Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Arch. Neurol. 60 (2003) 940-946
36. Ganuza E., Anderson A.J., and Ratledge C. High-cell-density cultivation of Schizochytrium sp. in an ammonium/pH-auxostat fed-batch system. Biotechnol. Lett. 30 (2008) 1559-1564
37. Ratledge C. Fatty acid biosynthesis in microorganisms being used for single cell oil production. Biochimie 86 (2004) 807-815
38. Ganuza E., Benitez-Santana T., Atalah E., et al. Crypthecodinium cohnii and Schizochytrium sp. as potential substitutes to fisheries derived oils in Sparus aurata microdiets. Aquaculture 277 (2008) 109-116
39. Arterburn L.M., Oken H.A., Hoffman J.P., et al. Bioequivalence of docosahexaenoic acid from different algal oils in capsules and in a DHA-fortified food. Lipids 42 (2007) 1011-1024
40. van Beelen V.A., Roeleveld J., Mooibroek H., et al. A comparative study on the effect of algal and fish oil on viability and cell proliferation of Caco-2 cells. Food Chem. Toxicol. 45 (2007) 716-724
41. Hsiao T.Y., and Blanch H.W. Physiological studies of eicosapentaenoic acid production in the marine microalga Glossomastix chrysoplasta. Biotechnol. Bioeng. 93 (2006) 465-475
42. Burla A.M., Radianingtyas H., Windest A., and Barrow C.J. Isolation and characterisation of polyunsaturated fatty acid producing Thraustochytrium species: screening of strains and optimisation of omega-3 production. Appl. Microbiol. Biotechnol. 72 (2006) 1161-1169