Biological activity of two botulinum toxin type A complexes (Dysport ® and Botox®) in volunteers : AA double-blind, randomized, dose-ranging study

Journal of Neurology

Volumn 255, Issue 12, 2008, Pages 1932-1939

  Wohlfarth, K ^a,b   Schwandt, I ^b   Wegner, F ^b   Jurgens T ^c   Gelbrich, G ^d   Wagner, A ^b   Bogdahn, U ^c   Schulte Mattler, W ^c  

^a HELIOS Klinikum Bad Saarow   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c UNIVERSITY OF REGENSBURG   (Germany)

^d Clinical Trial Centre Leipzig   (Germany)

Author keywords

Botox; Botulinum toxin; Dose equivalence; Dysport; Randomized controlled trial

Indexed keywords

BOTULINUM TOXIN A;

ABSENCE OF SIDE EFFECTS; ADULT; ARTICLE; BIOEQUIVALENCE; BIOLOGICAL ACTIVITY; CLINICAL ASSESSMENT; CLINICAL TRIAL; CONCENTRATION (PARAMETERS); CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG DIFFUSION; DRUG DOSAGE FORM COMPARISON; DRUG EFFECT; DRUG FORMULATION; DRUG SAFETY; ELECTRONEUROGRAPHY; EXTENSOR DIGITORUM BREVIS; EXTENSOR MUSCLE; FEMALE; HUMAN; MALE; MUSCLE ACTION POTENTIAL; NORMAL HUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ACTION POTENTIALS; ADOLESCENT; ADULT; BOTULINUM TOXIN TYPE A; CHEMISTRY, PHARMACEUTICAL; DIFFUSION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG COMBINATIONS; FEMALE; HUMANS; MALE; MIDDLE AGED; MUSCLE, SKELETAL; ORGAN SPECIFICITY; PROSPECTIVE STUDIES; YOUNG ADULT;

EID: 67349097370     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-008-0031-7     Document Type: Article

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