Persistent inflammatory pain decreases the antinociceptive effects of the mu opioid receptor agonist DAMGO in the locus coeruleus of male rats

Neuropharmacology

Volumn 56, Issue 6-7, 2009, Pages 1017-1026

  Jongeling, Amy C ^a,b   Johns, Malcolm E ^c   Murphy, Anne Z ^c   Hammond, Donna L ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c GEORGIA STATE UNIVERSITY   (United States)

Author keywords

Anti hyperalgesia; Antinociception; Complete Freund's adjuvant; CTAP; DAMGO; Mu opioid receptor

Indexed keywords

ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; MU OPIATE RECEPTOR; OPIATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG RECEPTOR BINDING; INFLAMMATION; ISOTHERM; LOCUS CERULEUS; MALE; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; SINGLE DRUG DOSE;

ANIMALS; DOWN-REGULATION; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; FREUND'S ADJUVANT; HYPERALGESIA; INFLAMMATION; LOCUS COERULEUS; MALE; MICROINJECTIONS; OPIOID PEPTIDES; PAIN; PEPTIDE FRAGMENTS; RATS; RECEPTORS, OPIOID, MU; SOMATOSTATIN;

EID: 67349087273     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2009.02.005     Document Type: Article

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