The Aryl-hydrocarbon receptor does not require the p23 co-chaperone for ligand binding and target gene expression in vivo

Toxicology Letters

Volumn 189, Issue 1, 2009, Pages 57-62

  Flaveny, Colin ^a   Perdew, Gary H ^a   Miller III, Charles A ^b  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b TULANE UNIVERSITY   (United States)

Author keywords

AHR; HSP90; p23; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; HYPOXIA INDUCIBLE FACTOR 1BETA; IMMUNOPHILIN; PROTEIN P23; UNCLASSIFIED DRUG; XAP2 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; FETUS; FETUS LIVER; GENE EXPRESSION; IN VIVO STUDY; LIGAND BINDING; LIVER TOXICITY; LIVER WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; SIGNAL TRANSDUCTION;

ANIMALS; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; FEMALE; GENE EXPRESSION; HETEROZYGOTE; HOMOZYGOTE; INTRAMOLECULAR OXIDOREDUCTASES; LIGANDS; LIVER; MICE; MICE, KNOCKOUT; PROTEIN BINDING; PROTEIN STABILITY; RECEPTORS, ARYL HYDROCARBON; TETRACHLORODIBENZODIOXIN;

HEPATITIS B VIRUS; MUS;

EID: 67349083878     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.05.002     Document Type: Article

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