Relationship of vitamin B12 deficiency with overweight in male Jordanian youth

Journal of Applied Sciences

Volumn 8, Issue 17, 2008, Pages 3060-3063

  Abu Samak, Mahmoud ^a   Khuzaie, Rula ^a   Abu Hasheesh, Mohammad ^a   Jaradeh, Malak ^a   Fawzi, Mohammad ^a  

^a APPLIED SCIENCE PRIVATE UNIVERSITY   (Jordan)

Author keywords

BMI; Body mass index; Folic acid; Leptin; Obesity; Overweight; Vitamin B12

Indexed keywords

BMI; BODY MASS INDEX; FOLIC ACIDS; LEPTIN; OBESITY; OVERWEIGHT; VITAMIN B-12;

HEALTH; HORMONES; ORGANIC ACIDS; STUDENTS;

BODY FLUIDS;

EID: 67149120672     PISSN: 18125654     EISSN: 18125662     Source Type: Journal    
DOI: 10.3923/jas.2008.3060.3063     Document Type: Article

References (30)

1. Atamer, A., B. Demir, G. Bayhan, Y. Atamer, N. Ilhan and Z. Akkus, 2008. Serum levels of leptin and homocysteine in women with polycystic ovary syndrome and its relationship to endocrine, clinical and metabolic parameters. J. Int. Med. Res., 36: 96-105.
2. Carretti, N.G., A. Ditto and C.G Guidom, 1998. Vitamin B12 levels in pregnancy influence erythropoietin response to anemia. Eur. J. Obstet. Gynecol. Reprod. Biol., 80: 63-66.
3. Claycombe, K., L.E. King and P.J. Fraker, 2008. A role for leptin in sustaining lymphopoiesis and myelopoiesis. Proc. Natl. Acad. Sci., 105: 2017-2021.
4. Cymbaluk, A., A. Chudecka-Glaz and I. Rzepka-Górska, 2008. Leptin levels in serum depending on Body Mass Index in patients with endometrial hyperplasia and cancer. Eur. J. Obstet Gynecol. Reprod. Biol., 136: 74-87.
5. Eikelis, N. and M. Esler, 2005. The neurobiology of human obesity. Exp. Physiol, 90: 673-682.
6. Fakhrzadeh, H., S. Ghotbi, R. Pourebrahim, M. Nouri, R. Heshmat, F. Bandarian, A. Shafaee and B. Larijani, 2006. Total plasma homocysteine, folate and vitamin B12 status in healthy Iranian adults: The Tehran homocysteine survey (2003-2004)/a cross-sectional population based study. BMC Public Health, 13: 6-29.
7. Flier, J.S., 1997. Leptin expression and action: New experimental paradigms. Proc. Natl. Acad. Sci. USA., 94: 4242-4245.
8. Fora, M.A. and M.A. Mohammad, 2005. High frequency of suboptimal serum vitamin B12 level in adults in Jordan. Saudi Med. J., 26: 1591-1595.
9. Garanty-Bogacka, B., M. Syrenicz, P. Szolomicka-Kurzawa, A. Gebala, J. Goral and B. Krupa, 2006. Correlation between serum homocysteine levels and selected atherosclerosis risk factors in children and adolescents with simple obesity. Przegl. Lek., 63: 645-649.
10. Gupta, N.K. and J. S. Powers, 2008. Vitamin B12 deficiency and severe weight loss in an elderly patient. Term. Med., 101: 35-36.
11. Hao, L., J. Ma, J. Zhu, MJ. Stampfer, Y. Tian, W.C. Willett and Z. Li, 2007. Vitamin B12 deficiency is prevalent in 35- to 64-year-old Chinese adults. J. Nutr., 137: 1278-1285.
12. Holst-Schumacher, I., R. Monge-Rojas and M. Barrantes-Santamaría, 2007. Prevalence of mild serum vitamin B(12) deficiency in rural and urban Costa Rican young adults. Rev. Panam. Salud. Publ., 22: 396-401.
13. Hung, S.C., T.Y. Tung and C.S. Yang, 2005. High-calorie supplementation increases serum leptin levels and improves response to rHuEPO in long-term hemodialysis patients. Am. J. Kidney Dis., 45: 1073-1083.
14. Jauréguy, M. and G. Choukroun, 2006. Factors affecting the response to erythropoiesis-stimulating agents. Nephrol. Ther., 1 4: 274-282.
15. Johnson, M.A., 2007. If high folic acid aggravates vitamin B12 deficiency what should be done about it? Nutr. Rev., 65: 451-458.
16. Khanduri, U. and A. Sharma, 2007. Megaloblastic anaemia: Prevalence and causative factors. Natl. Med. J. India, 20: 172-175.
17. Martos, R, M. Valle, R. Morales, R. Cañete, M.I. Gavilan and V. Sánchez-Margalet, 2006. Hyperhomo-cysteinemia correlates with insulin resistance and low-grade systemic inflammation in obese prepubertal children. Metabolism, 55: 72-77.
18. Meertens, L., N. Diaz, L. Solano, M.A. Baron and A. Rodriguez, 2007. Serum homocysteine, folate and vitamin B12 in Venezuelan elderly. Arch. Latinoam. Nutr., 57: 26-32.
19. Narin, F., M.E. Atabek, M. Karakukcu, N. Narin, S. Kurtoglu, H. Gumus, B. Coksevim and R. Erez, 2005. The association of plasma homocysteine levels with serum leptin and apolipoprotein B levels in childhood obesity. Ann. Saudi Med., 25: 209-214.
20. Papandreou, D., I. Rousso, A. Makedou, M. Arvanitidou and I. Mavromichalis 2007. Association of blood pressure, obesity and serum homocysteine levels in healthy children. Acta Paediatr., 96: 1819-1823.
21. Pelleymounter, M.A., 1995. Effects of the obese gene product on body weight regulation in ob/ob mice. Science, 269: 540-543.
22. Pinhas-Hamiel, O., N. Doron-Panush, B. Reichman, D. Nitzan-Kaluski, S. Shalitin and L. Geva-Lerner, 2006. Obese children and adolescents: A risk group for low vitamin B12 concentration. Arch. Pediatr. Adolesc. Med., 160: 933-936.
23. Quinlivan, E.P., 2008. In vitamin B12 deficiency, higher serum folate is associated with increased homocysteine and methylmalonic acid concentrations. Proc. Natl. Acad. Sci. USA., 105 (5): Online www.pnas.org/cgi/context/extract/105/5/E7.
24. Rafail, S., K. Ritis, K. Schaefer, I. Kourtzelis, M. Speletas, M. Doumas, S. Giaglis, K. Kambas, S. Konstantinides and G. Kartalis, 2008. Leptin induces the expression of functional tissue factor in human neutrophils and peripheral blood mononuclear cells through JAK2-dependent mechanisms and TNFalpha involvement. Thromb. Res., Feb 26, www.ncbi.nlm.nih.gov/pubmed/18308368.
25. Strassburg, A., C. Krems, P.M. Lührmann, B. Hartmann and M. Neuhäuser-Beithold, 2004. Effect of age on plasma homocysteine concentrations in young and elderly subjects considering serum vitamin concentrations and different lifestyle factors. Int. J. Vitamin Nutr. Res., 74: 129-136.
26. Thauvin-Robinet, C. and E. Roze, 2007. Cobalamin metabolism disorders in adult patients. Rev. Neurol. (Paris), 163: 911-918.
27. Thawnashom, K., R. Tungtrongchitr, S. Petmitr, P. Pongpaew, B. Phonrat, A. Tungtrongchitr and F.P. Schelp, 2005. Methylenetetrahydrofolate reductase (MTHFR) polymorphism (C677T) in relation to homocysteine concentration in overweight and obese Thais. Southeast Asian J. Trop. Med. Public Health, 36: 459-466.
28. Tritos, N.A. and C.S. Mantzoros, 1997. Leptin: Its role in obesity and beyond. Diabetologia, 40: 1371-1379.
29. Wiersinga, W. J., S.E. de Rooij, J.G. Huijmans, C. Fischer and J.B. Hoekstra, 2006. Diagnosis of vitamin B12 deficiency. Ned. Tijdschr. Geneeskd., 10: 2789-2794.
30. Zhang, Y., 1994. Positional cloning of the mouse obese gene and its human homologue. Nature, 372: 425-432.