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Volumn 29, Issue 23, 2009, Pages 7392-7394

Mice expressing mutant parkin exhibit hallmark features of Parkinson's disease

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PARKIN; TYROSINE 3 MONOOXYGENASE;

EID: 67049168878     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1719-09.2009     Document Type: Note
Times cited : (3)

References (27)
  • 1
    • 0036468432 scopus 로고    scopus 로고
    • Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease
    • Auluck PK, Chan HY, Trojanowski JQ, Lee VM, Bonini NM (2002) Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science 295:865-868.
    • (2002) Science , vol.295 , pp. 865-868
    • Auluck, P.K.1    Chan, H.Y.2    Trojanowski, J.Q.3    Lee, V.M.4    Bonini, N.M.5
  • 3
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: Mechanisms and models
    • DOI 10.1016/S0896-6273(03)00568-3
    • Dauer W, Przedborski S (2003) Parkinson's disease: mechanisms and models. Neuron 39:889-909. (Pubitemid 37130207)
    • (2003) Neuron , vol.39 , Issue.6 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 5
    • 0037118259 scopus 로고    scopus 로고
    • Neuronal α-synucleinopathy with severe movement disorder in mice expressing A53T human α-synuclein
    • DOI 10.1016/S0896-6273(02)00682-7
    • Giasson BI, Duda JE, Quinn SM, Zhang B, Trojanowski JQ, Lee VM (2002) Neuronal α-synucleinopathy with severe movement disorder in mice expressing A53T human α-synuclein. Neuron 34:521-533. (Pubitemid 34628750)
    • (2002) Neuron , vol.34 , Issue.4 , pp. 521-533
    • Giasson, B.I.1    Duda, J.E.2    Quinn, S.M.3    Zhang, B.4    Trojanowski, J.Q.5    Lee, V.M.-Y.6
  • 12
    • 34250372427 scopus 로고    scopus 로고
    • Deciphering the role of heterozygous mutations in genes associated with parkinsonism
    • DOI 10.1016/S1474-4422(07)70174-6, PII S1474442207701746
    • Klein C, Lohmann-Hedrich K, Rogaeva E, Schlossmacher MG, Lang AE (2007) Deciphering the role of heterozygous mutations in genes associated with parkinsonism. Lancet Neurol 6:652-662. (Pubitemid 46921058)
    • (2007) Lancet Neurology , vol.6 , Issue.7 , pp. 652-662
    • Klein, C.1    Lohmann-Hedrich, K.2    Rogaeva, E.3    Schlossmacher, M.G.4    Lang, A.E.5
  • 14
    • 47249138600 scopus 로고    scopus 로고
    • Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1: A new genetic model for Parkinson's disease?
    • Le Pen G, Sonnier L, Hartmann A, Bizot JC, Trovero F, Krebs MO, Prochiantz A (2008) Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1: a new genetic model for Parkinson's disease? Parkinsonism Relat Disord 14:S107-S111.
    • (2008) Parkinsonism Relat Disord , vol.14
    • Le Pen, G.1    Sonnier, L.2    Hartmann, A.3    Bizot, J.C.4    Trovero, F.5    Krebs, M.O.6    Prochiantz, A.7
  • 16
    • 60849106352 scopus 로고    scopus 로고
    • Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant α-synuclein
    • Lu XH, Fleming SM, Meurers B, Ackerson LC, Mortazavi F, Lo V, Hernandez D, Sulzer D, Jackson GR, Maidment NT, Chesselet MF, Yang XW (2009) Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant α-synuclein. J Neurosci 29:1962-1976.
    • (2009) J Neurosci , vol.29 , pp. 1962-1976
    • Lu, X.H.1    Fleming, S.M.2    Meurers, B.3    Ackerson, L.C.4    Mortazavi, F.5    Lo, V.6    Hernandez, D.7    Sulzer, D.8    Jackson, G.R.9    Maidment, N.T.10    Chesselet, M.F.11    Yang, X.W.12
  • 18
    • 0034681471 scopus 로고    scopus 로고
    • Dopaminergic loss and inclusion body formation in α-synuclein mice: Implications for neurodegenerative disorders
    • DOI 10.1126/science.287.5456.1265
    • Masliah E, Rockenstein E, Veinbergs I, Mallory M, Hashimoto M, Takeda A, Sagara Y, Sisk A, Mucke L (2000) Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders. Science 287:1265-1269. (Pubitemid 30112148)
    • (2000) Science , vol.287 , Issue.5456 , pp. 1265-1269
    • Masliah, E.1    Rockenstein, E.2    Veinbergs, I.3    Mallory, M.4    Hashimoto, M.5    Takeda, A.6    Sagara, Y.7    Sisk, A.8    Mucke, L.9
  • 19
    • 33748300291 scopus 로고    scopus 로고
    • Behavioral models of Parkinsons disease in rodents: A new look at an old problem
    • DOI 10.1002/mds.21010
    • Meredith GE, Kang UJ (2006) Behavioral models of Parkinson's disease in rodents: a new look at an old problem. Mov Disord 21:1595-1606. (Pubitemid 44742185)
    • (2006) Movement Disorders , vol.21 , Issue.10 , pp. 1595-1606
    • Meredith, G.E.1    Kang, U.J.2
  • 20
    • 53449093161 scopus 로고    scopus 로고
    • Value of genetic models in understanding the cause and mechanisms of Parkinson's disease
    • Moore DJ, Dawson TM (2008) Value of genetic models in understanding the cause and mechanisms of Parkinson's disease. Curr Neurol Neurosci Rep 8:288-296.
    • (2008) Curr Neurol Neurosci Rep , vol.8 , pp. 288-296
    • Moore, D.J.1    Dawson, T.M.2
  • 21
    • 0345189364 scopus 로고    scopus 로고
    • Yeast Cells Provide Insight into Alpha-Synuclein Biology and Pathobiology
    • DOI 10.1126/science.1090439
    • Outeiro TF, Lindquist S (2003) Yeast cells provide insight into alpha-synuclein biology and pathobiology. Science 302:1772-1775. (Pubitemid 37505742)
    • (2003) Science , vol.302 , Issue.5651 , pp. 1772-1775
    • Outeiro, T.F.1    Lindquist, S.2
  • 23
    • 33846804056 scopus 로고    scopus 로고
    • A Drosophila model of mutant human parkin-induced toxicity demonstrates selective loss of dopaminergic neurons and dependence on cellular dopamine
    • Sang TK, Chang HY, Lawless GM, Ratnaparkhi A, Mee L, Ackerson LC, Maidment NT, Krantz DE, Jackson GR (2007) A Drosophila model of mutant human parkin-induced toxicity demonstrates selective loss of dopaminergic neurons and dependence on cellular dopamine. J Neurosci 27:981-992.
    • (2007) J Neurosci , vol.27 , pp. 981-992
    • Sang, T.K.1    Chang, H.Y.2    Lawless, G.M.3    Ratnaparkhi, A.4    Mee, L.5    Ackerson, L.C.6    Maidment, N.T.7    Krantz, D.E.8    Jackson, G.R.9
  • 25
    • 34547885021 scopus 로고    scopus 로고
    • Drosophila overexpressing parkin R275W mutant exhibits dopaminergic neuron degeneration and mitochondrial abnormalities
    • Wang C, Lu R, Ouyang X, Ho MW, Chia W, Yu F, Lim KL (2007) Drosophila overexpressing parkin R275W mutant exhibits dopaminergic neuron degeneration and mitochondrial abnormalities. J Neurosci 27:8563-8570.
    • (2007) J Neurosci , vol.27 , pp. 8563-8570
    • Wang, C.1    Lu, R.2    Ouyang, X.3    Ho, M.W.4    Chia, W.5    Yu, F.6    Lim, K.L.7
  • 27
    • 59149102707 scopus 로고    scopus 로고
    • Molecular basis of Parkinson's disease
    • Yang YX, Wood NW, Latchman DS (2009) Molecular basis of Parkinson's disease. Neuroreport 28; 20:150-156.
    • (2009) Neuroreport , vol.28 , Issue.20 , pp. 150-156
    • Yang, Y.X.1    Wood, N.W.2    Latchman, D.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.