Reply to Klemba: Intracellular processing of the membrane-bound PfA-M1 neutral aminopeptidase, a target for new antimalarials

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 22, 2009, Pages

  Whisstock, James C ^a   McGowan, Sheena ^a   Trenholme, Katharine R ^b   Gardiner, Donald L ^b   Dalton, John P ^c  

^a MONASH UNIVERSITY   (Australia)

^b QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^c UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

MICROSOMAL AMINOPEPTIDASE;

CATALYSIS; CELL VACUOLE; CYTOSOL; LETTER; MEMBRANE BINDING; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN DEGRADATION;

EID: 67049155536     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0903872106     Document Type: Letter

References (4)

1. Klemba M (2009) On the location of the aminopeptidase N homolog PfA-M1 in Plasmodium falciparum. Proc Natl Acad Sci USA 10.1073/pnas.0903493106.
2. McGowan S, et al. (2009) Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase. Proc Natl Acad Sci USA 106:2537-2542.
3. Florent I, et al. (1998) A Plasmodium falciparum aminopeptidase gene belonging to the M1 family of zinc-metallopeptidases is expressed in erythrocytic stages. Mol Biochem Parasitol 97:149-160.
4. Allary M, Schrevel J, Florent I (2002) Properties, stage-dependent expression and localization of Plasmodium falciparum M1 family zinc-aminopeptidase. Parasitology 125(Pt 1):1-10.