2-Phenylquinolones as inhibitors of the HIV-1 Tat-TAR interaction

ChemMedChem

Volumn 4, Issue 6, 2009, Pages 935-938

  Gatto, Barbara ^a   Tabarrini, Oriana ^b   Massari, Serena ^b   Giaretta, Giulia ^a   Sabatini, Stefano ^b   Del Vecchio, Claudia ^a   Parolin, Cristina ^a   Fravolini, Arnaldo ^b   Palumbo, Manlio ^a   Cecchetti, Violetta ^b  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF PERUGIA   (Italy)

Author keywords

2 phenylquinolones; Antiviral agents; Fluorescence quenching assay; Medicinal chemistry; Tat TAR inhibitors

Indexed keywords

2 PHENYLQUINOLONE DERIVATIVE; PIPERAZINE DERIVATIVE; PIPERIDINE DERIVATIVE; QUINOLONE DERIVATIVE; REGULATOR PROTEIN; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; GENE EXPRESSION REGULATION; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LONG TERMINAL REPEAT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION; TRANSACTIVATOR RESPONSE REGION; VIRUS INHIBITION; VIRUS MORPHOLOGY; VIRUS REPLICATION;

AMINO ACID SEQUENCE; ANTI-HIV AGENTS; CELL LINE; HIV LONG TERMINAL REPEAT; HIV-1; HUMANS; JURKAT CELLS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; QUINOLONES; STRUCTURE-ACTIVITY RELATIONSHIP; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS;

EID: 67049143076     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.200800437     Document Type: Article

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