Inhibition of apoB secretion from HepG2 cells by insulin is amplified by naringenin, independent of the insulin receptor

Journal of Lipid Research

Volumn 49, Issue 10, 2008, Pages 2218-2229

  Allister, Emma M ^a   Mulvihill, Erin E ^a   Barrett, P Hugh R ^b   Edwards, Jane Y ^a   Carter, Lindsey P ^a   Huff, Murray W ^a  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Apolipoprotein B; Citrus flavonoid:; Degradation; Kinetics; LDL receptor; Microsomal triglyceride transfer protein; Mitogen activated protein kinase extracellular regulated kinase; Multicompartmental modeling; Oleate; Phosphoinositide 3 kinase

Indexed keywords

APOLIPOPROTEIN B; APOLIPOPROTEIN B100; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; LOW DENSITY LIPOPROTEIN RECEPTOR; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NARINGENIN; PHOSPHATIDYLINOSITOL 3 KINASE;

ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INSULIN RESISTANCE; LIPOPROTEIN SECRETION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOLIPOPROTEIN B-100; CARRIER PROTEINS; CATTLE; CELL LINE, TUMOR; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVANONES; GENE EXPRESSION REGULATION; HEPATOCYTES; HUMANS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; KINETICS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; RECEPTOR, INSULIN; RECEPTORS, LDL;

EID: 67049138804     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M800297-JLR200     Document Type: Article

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