MPP + impairs autophagic clearance of alpha-synuclein by impairing the activity of dynein

NeuroReport

Volumn 20, Issue 6, 2009, Pages 569-573

  Cai, Zeng Lin ^a,b   Shi, Ji Jun ^a   Yang, Ya Ping ^a   Cao, Bi Yin ^a   Wang, Feng ^a   Huang, Jin Zhong ^a   Yang, Fang ^a   Zhang, Ping ^a   Liu, Chun Feng ^a  

^a SOOCHOW UNIVERSITY   (China)

^b XUZHOU MEDICAL UNIVERSITY   (China)

Author keywords

synuclein; 1 methyl 4 phenylpyridinium; Autophagy; Dynein; LC3 II; Parkinson's disease

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; ALPHA SYNUCLEIN; CATALASE; DYNEIN ADENOSINE TRIPHOSPHATASE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; SUPEROXIDE DISMUTASE; ENZYME INHIBITOR; LAMP1 PROTEIN, RAT; LC3 PROTEIN, RAT; LYSOSOME ASSOCIATED MEMBRANE PROTEIN; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN; STAUROSPORINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; UPREGULATION; ANIMAL; AUTOPHAGY; CELL STRAIN; CYTOPLASM; DRUG EFFECT; LYSOSOME; METABOLISM; NERVE CELL; PHYSIOLOGY;

1-METHYL-4-PHENYLPYRIDINIUM; ALPHA-SYNUCLEIN; ANIMALS; AUTOPHAGY; CATALASE; CYTOPLASM; DYNEIN ATPASE; ENZYME INHIBITORS; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; LYSOSOMES; MICROTUBULE-ASSOCIATED PROTEINS; NEURONS; PC12 CELLS; RATS; RNA, MESSENGER; STAUROSPORINE; SUPEROXIDE DISMUTASE;

EID: 67049137602     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/WNR.0b013e32832986c4     Document Type: Article

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