Single-molecule mechanics: New insights from the escape-over-a-barrier problem

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 22, 2009, Pages 8795-8796

  Dudko, Olga K ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL STRUCTURE; MACROMOLECULE; MOLECULAR INTERACTION; MOLECULAR MECHANICS; MOLECULE; NOTE; PRIORITY JOURNAL; SPECTROSCOPY;

BIOPHYSICAL PROCESSES; CELLS; MECHANICAL PROCESSES; MODELS, CHEMICAL; THERMODYNAMICS;

EID: 67049115585     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0904156106     Document Type: Note

References (15)

1. Greenleaf WJ, Woodside MT, Block SM (2007) High-resolution, single-molecule measurements of biomolecular motion. Annu Rev Biophys Biomol Struct 36:171-190. (Pubitemid 46998115)
2. Bustamante C (2008) In singulo biochemistry: When less is more. Annu Rev Biochem 77:45-50.
3. Freund LB (2009) Characterizing the resistance generated by a molecular bond as it is forcibly separated. Proc Natl Acad Sci USA 106:8818-8823.
4. Evans E, Ritchie K (1997) Dynamic strength of molecular adhesion bonds. Biophys J 72:1541-1555. (Pubitemid 27133095)
5. Rief M, Gautel M, Oesterhelt F, Fernandez JM, Gaub HE (1997) Reversible unfolding of individual titin immunoglobulin domains by AFM. Science 276:1109-1112. (Pubitemid 27218118)
6. Izrailev S, Stepaniants S, Balsera M, Oono Y, Schulten K (1997) Molecular dynamics study of unbinding of the avidin-biotin complex. Biophys J 72:1568-1581. (Pubitemid 27133097)
7. Kramers HA (1940) Brownian motion in the field of force and the diffusion model of chemical reactions. Physica 7:284-304.
8. Hummer G, Szabo A (2003) Kinetics from nonequilibrium single-molecule pulling experiments. Biophys J 85:5-15. (Pubitemid 36753612)
9. Dudko OK, Filippov AE, Klafter J, Urbakh M (2003) Beyond the conventional description of dynamic force spectroscopy of adhesion bonds. Proc Natl Acad Sci USA 100:11378-11381. (Pubitemid 37205943)
10. Dudko OK, Hummer G, Szabo (2006) A Intrinsic rates and activation free energies from single-molecule pulling experiments. Phys Rev Lett 96:108101.
11. Tshiprut Z, Klafter J, Urbakh M (2008) Single-molecule pulling experiments: When the stiffness of the pulling device matters. Biophys J 95:L42-L44.
12. Dudko OK, Hummer G, Szabo A (2008) Theory, analysis, and interpretation of single-molecule force spectroscopy experiments. Proc Natl Acad Sci USA 105:15755-15760.
13. Hyeon C, Thirumalai D (2003) Can energy landscape roughness of proteins and RNA be measured using mechanical unfolding experiments? Proc Natl Acad Sci USA (2003) 100:10249-10253. (Pubitemid 37071864)
14. Greenleaf WJ, Frieda KL, Foster D, Woodside MT, Block SM (2008) Direct observation of hierarchical folding in single riboswitch aptamers. Science 319:630-633. (Pubitemid 351197067)
15. Onuchic JN, Wolynes PG (2004) Theory of protein folding. Curr Opin Struct Biol 14:70-75. (Pubitemid 38249595)