메뉴 건너뛰기




Volumn 8, Issue 6, 2009, Pages 729-745

Challenges and progress in the development of a serogroup B meningococcal vaccine

Author keywords

5CVMB; Meningococcal disease; Outer membrane protein; Outer membrane vesicle vaccine; Serogroup B

Indexed keywords

MENINGOCOCCUS VACCINE;

EID: 67049114125     PISSN: 14760584     EISSN: 17448395     Source Type: Journal    
DOI: 10.1586/erv.09.30     Document Type: Review
Times cited : (25)

References (153)
  • 2
    • 33745446358 scopus 로고    scopus 로고
    • Ascertainment of meningococcal disease in Europe
    • Trotter C, Samuelsson S, Perrocheau A et al. Ascertainment of meningococcal disease in Europe. Euro. Surveill. 10(12), 247-250 (2005).
    • (2005) Euro. Surveill. , vol.10 , Issue.12 , pp. 247-250
    • Trotter, C.1    Samuelsson, S.2    Perrocheau, A.3
  • 3
    • 0020690792 scopus 로고
    • Meningococcal disease: Still with us
    • Peltola H. Meningococcal disease: still with us. Rev. Infect. Dis. 5(1), 71-91 (1983).
    • (1983) Rev. Infect. Dis. , vol.5 , Issue.1 , pp. 71-91
    • Peltola, H.1
  • 4
    • 0035888124 scopus 로고    scopus 로고
    • Planning, registration, and implementation of an immunisation campaign against meningococcal serogroup C disease in the UK: A success story
    • DOI 10.1016/S0264-410X(01)00299-7, PII S0264410X01002997
    • Miller E, Salisbury D, Ramsay M. Planning, registration, and implementation of an immunisation campaign against meningococcal serogroup C disease in the UK: a success story. Vaccine 20(Suppl. 1), S58-S67 (2001). (Pubitemid 32925012)
    • (2001) Vaccine , vol.20 , Issue.SUPPL. 1
    • Miller, E.1    Salisbury, D.2    Ramsay, M.3
  • 5
    • 0037442694 scopus 로고    scopus 로고
    • Herd immunity from meningococcal serogroup C conjugate vaccination in England: Database analysis
    • Ramsay ME, Andrews NJ, Trotter CL, Kaczmarski EB, Miller E. Herd immunity from meningococcal serogroup C conjugate vaccination in England: database analysis. BMJ 326(7385), 365-366 (2003). (Pubitemid 36241472)
    • (2003) British Medical Journal , vol.326 , Issue.7385 , pp. 365-366
    • Ramsay, M.E.1    Andrews, N.J.2    Trotter, C.L.3    Kaczmarski, E.B.4    Miller, E.5
  • 6
    • 3242768475 scopus 로고    scopus 로고
    • Effectiveness of meningococcal serogroup C conjugate vaccine 4 years after introduction
    • DOI 10.1016/S0140-6736(04)16725-1, PII S0140673604167251
    • Trotter CL, Andrews NJ, Kaczmarski EB, Miller E, Ramsay ME. Effectiveness of meningococcal serogroup C conjugate vaccine 4 years after introduction. Lancet 364(9431), 365-367 (2004). (Pubitemid 38970013)
    • (2004) Lancet , vol.364 , Issue.9431 , pp. 365-367
    • Trotter, C.L.1    Andrews, N.J.2    Kaczmarski, E.B.3    Miller, E.4    Ramsay, M.E.5
  • 7
    • 15044351797 scopus 로고    scopus 로고
    • New vaccine should ease meningitis fears
    • DOI 10.1001/jama.293.12.1433
    • Mitka M. New vaccine should ease meningitis fears. JAMA 293(12), 1433-1434 (2005). (Pubitemid 40393280)
    • (2005) Journal of the American Medical Association , vol.293 , Issue.12 , pp. 1433-1434
    • Mitka, M.1
  • 8
    • 13844271447 scopus 로고    scopus 로고
    • The future of meningococcal vaccines
    • DOI 10.1097/01.inf.0000154438.37306.ab
    • Healy CM, Baker CJ. The future of meningococcal vaccines. Pediatr. Infect. Dis. J. 24(2), 175-176 (2005). (Pubitemid 40250778)
    • (2005) Pediatric Infectious Disease Journal , vol.24 , Issue.2 , pp. 175-176
    • Healy, C.M.1    Baker, C.J.2
  • 9
    • 53749097950 scopus 로고    scopus 로고
    • Vaccination coverage among adolescents aged 13-17 years - United States, 2007
    • Vaccination coverage among adolescents aged 13-17 years - United States, 2007. MMWR Morb. Mortal. Wkly Rep. 57(40), 1100-1103 (2008).
    • (2008) MMWR Morb. Mortal. Wkly Rep. , vol.57 , Issue.40 , pp. 1100-1103
  • 10
    • 38049098648 scopus 로고    scopus 로고
    • Immunogenicity of a tetravalent meningococcal glycoconjugate vaccine in infants
    • Snape MD, Perrett KP, Ford K et al. Immunogenicity of a tetravalent meningococcal glycoconjugate vaccine in infants. JAMA 299, 173-184 (2008).
    • (2008) JAMA , vol.299 , pp. 173-184
    • Snape, M.D.1    Perrett, K.P.2    Ford, K.3
  • 11
    • 0015422337 scopus 로고
    • Immunologic response of man to group B meningococcal polysaccharide vaccines
    • Wyle FA, Artenstein MS, Brandt BL et al. Immunologic response of man to group B meningococcal polysaccharide vaccines. J. Infect. Dis. 126(5), 514-521 (1972).
    • (1972) J. Infect. Dis. , vol.126 , Issue.5 , pp. 514-521
    • Wyle, F.A.1    Artenstein, M.S.2    Brandt, B.L.3
  • 12
    • 0031029970 scopus 로고    scopus 로고
    • Preclinical evaluation of group B Neisseria meningitidis and Escherichia coli K92 capsular polysaccharide-protein conjugate vaccines in juvenile rhesus monkeys
    • Devi SJ, Zollinger WD, Snoy PJ et al. Preclinical evaluation of group B Neisseria meningitidis and Escherichia coli K92 capsular polysaccharide-protein conjugate vaccines in juvenile rhesus monkeys. Infect. Immun. 65(3), 1045-1052 (1997). (Pubitemid 27088008)
    • (1997) Infection and Immunity , vol.65 , Issue.3 , pp. 1045-1052
    • Devi, S.J.N.1    Zollinger, W.D.2    Snoy, P.J.3    Tai, J.Y.4    Costantini, P.5    Norelli, F.6    Rappuoli, R.7    Frasch, C.E.8
  • 13
    • 0031030047 scopus 로고    scopus 로고
    • Bactericidal antibody responses of juvenile rhesus monkeys immunized with group B Neisseria meningitidis capsular polysaccharide-protein conjugate vaccines
    • Zollinger WD, Moran EE, Devi SJ, Frasch CE. Bactericidal antibody responses of juvenile rhesus monkeys immunized with group B Neisseria meningitidis capsular polysaccharide-protein conjugate vaccines. Infect. Immun. 65(3), 1053-1060 (1997). (Pubitemid 27088009)
    • (1997) Infection and Immunity , vol.65 , Issue.3 , pp. 1053-1060
    • Zollinger, W.D.1    Moran, E.E.2    Devi, S.J.N.3    Frasch, C.E.4
  • 14
    • 0020518256 scopus 로고
    • Antigenic similarities between brain components and bacteria causing meningitis. Implications for vaccine development and pathogenesis
    • Finne J, Leinonen M, Makela PH. Antigenic similarities between brain components and bacteria causing meningitis. Implications for vaccine development and pathogenesis. Lancet 2(8346), 355-357 (1983).
    • (1983) Lancet , vol.2 , Issue.8346 , pp. 355-357
    • Finne, J.1    Leinonen, M.2    Makela, P.H.3
  • 15
    • 36049006620 scopus 로고    scopus 로고
    • Lack of association between group B meningococcal disease and autoimmune disease
    • Howitz M, Krause TG, Simonsen JB et al. Lack of association between group B meningococcal disease and autoimmune disease. Clin. Infect. Dis. 45(10), 1327-1334 (2007).
    • (2007) Clin. Infect. Dis. , vol.45 , Issue.10 , pp. 1327-1334
    • Howitz, M.1    Krause, T.G.2    Simonsen, J.B.3
  • 16
    • 0022519159 scopus 로고
    • Induction of meningococcal group B polysaccharide-specific IgG antibodies in mice by using an N-propionylated B polysaccharide-tetanus toxoid conjugate vaccine
    • Jennings HJ, Roy R, Gamian A. Induction of meningococcal group B polysaccharide-specific IgG antibodies in mice by using an N-propionylated B polysaccharide-tetanus toxoid conjugate vaccine. J. Immunol. 137(5), 1708-1713 (1986). (Pubitemid 16014828)
    • (1986) Journal of Immunology , vol.137 , Issue.5 , pp. 1708-1713
    • Jennings, H.J.1    Roy, R.2    Gamian, A.3
  • 17
    • 0023236032 scopus 로고
    • N-propionylated group B meningococcal polysaccharide mimics a unique epitope on group B Neisseria meningitidis
    • DOI 10.1084/jem.165.4.1207
    • Jennings HJ, Gamian A, Ashton FE. N-propionylated group B meningococcal polysaccharide mimics a unique epitope on group B Neisseria meningitidis. J. Exp. Med. 165(4), 1207-1211 (1987). (Pubitemid 17064516)
    • (1987) Journal of Experimental Medicine , vol.165 , Issue.4 , pp. 1207-1211
    • Jennings, H.J.1    Gamian, A.2    Ashton, F.E.3
  • 18
    • 0024443030 scopus 로고
    • Protective efficacy of mouse serum to the N-propionyl derivative of meningococcal group B polysaccharide
    • DOI 10.1016/0882-4010(89)90087-9
    • Ashton FE, Ryan JA, Michon F, Jennings HJ. Protective efficacy of mouse serum to the N-propionyl derivative of meningococcal group B polysaccharide. Microb. Pathog. 6(6), 455-458 (1989). (Pubitemid 19223600)
    • (1989) Microbial Pathogenesis , vol.6 , Issue.6 , pp. 455-458
    • Ashton, F.E.1    Ryan, J.A.2    Michon, F.3    Jennings, H.J.4
  • 19
    • 67049120830 scopus 로고    scopus 로고
    • Protective anti- N-propionyl Neisseria meningitidis group B polysaccharide monoclonal antibodies are reactive with non-capsular antigens expressed by group A, B, C and W135 strains
    • Presented at
    • Moe GR, Flitter BA. Protective anti- N-propionyl Neisseria meningitidis group B polysaccharide monoclonal antibodies are reactive with non-capsular antigens expressed by group A, B, C and W135 strains. Presented at: International Pathogenic Neisseria Conference. Rotterdam, The Netherlands, 7-12 September 2008.
    • International Pathogenic Neisseria Conference. Rotterdam, the Netherlands, 7-12 September 2008
    • Moe, G.R.1    Flitter, B.A.2
  • 20
    • 1542301057 scopus 로고    scopus 로고
    • Clinical evaluation of a group B meningococcal N-propionylated polysaccharide conjugate vaccine in adult, male volunteers
    • DOI 10.1016/j.vaccine.2003.10.005, PII S0264410X03007321
    • Bruge J, Bouveret-Le Cam N, Danve B, Rougon G, Schulz D. Clinical evaluation of a group B meningococcal N-propionylated polysaccharide conjugate vaccine in adult, male volunteers. Vaccine 22(9-10), 1087-1096 (2004). (Pubitemid 38296650)
    • (2004) Vaccine , vol.22 , Issue.9-10 , pp. 1087-1096
    • Bruge, J.1    Cam, N.B.-L.2    Danve, B.3    Rougon, G.4    Schulz, D.5
  • 21
    • 0014531759 scopus 로고
    • Human immunity to the meningococcus. I. the role of humoral antibodies
    • • Describes how serum bactericidal antibody titers correlate with protection against meningococcal disease
    • Goldschneider I, Gotschlich EC, Artenstein MS. Human immunity to the meningococcus. I. The role of humoral antibodies. J. Exp. Med. 129(6), 1307-1326 (1969). • Describes how serum bactericidal antibody titers correlate with protection against meningococcal disease.
    • (1969) J. Exp. Med. , vol.129 , Issue.6 , pp. 1307-1326
    • Goldschneider, I.1    Gotschlich, E.C.2    Artenstein, M.S.3
  • 22
    • 0035112040 scopus 로고    scopus 로고
    • Serological basis for use of meningococcal serogroup C conjugate vaccines in the United Kingdom: Reevaluation of correlates of protection
    • DOI 10.1128/IAI.69.3.1568-1573.2001
    • Borrow R, Andrews N, Goldblatt D, Miller E. Serological basis for use of meningococcal serogroup C conjugate vaccines in the United Kingdom: reevaluation of correlates of protection. Infect. Immun. 69(3), 1568-1573 (2001). (Pubitemid 32187610)
    • (2001) Infection and Immunity , vol.69 , Issue.3 , pp. 1568-1573
    • Borrow, R.1    Andrews, N.2    Goldblatt, D.3    Miller, E.4
  • 23
    • 14844282302 scopus 로고    scopus 로고
    • Meningococcal surrogates of protection - Serum bactericidal antibody activity
    • DOI 10.1016/j.vaccine.2005.01.051
    • Borrow R, Balmer P, Miller E. Meningococcal surrogates of protection: serum bactericidal antibody activity. Vaccine 23(17-18), 2222-2227 (2005). (Pubitemid 40341456)
    • (2005) Vaccine , vol.23 , Issue.17-18 , pp. 2222-2227
    • Borrow, R.1    Balmer, P.2    Miller, E.3
  • 24
    • 0003473977 scopus 로고
    • Requirements for meningococcal polysaccharide vaccine
    • WHO. World Health Organization, Geneva, Switzerland
    • WHO. Requirements for meningococcal polysaccharide vaccine. In: World Health Organisation Technical Report Series. No. 594. World Health Organization, Geneva, Switzerland (1976).
    • (1976) World Health Organisation Technical Report Series. No. 594
  • 25
    • 0037472392 scopus 로고    scopus 로고
    • Serum bactericidal activity correlates with the vaccine efficacy of outer membrane vesicle vaccines against Neisseria meningitidis serogroup B disease
    • DOI 10.1016/S0264-410X(02)00591-1, PII S0264410X02005911
    • Holst J, Feiring B, Fuglesang JE et al. Serum bactericidal activity correlates with the vaccine efficacy of outer membrane vesicle vaccines against Neisseria meningitidis serogroup B disease. Vaccine 21(7-8), 734-737 (2003). (Pubitemid 36091989)
    • (2003) Vaccine , vol.21 , Issue.7-8 , pp. 734-737
    • Holst, J.1    Feiring, B.2    Fuglesang, J.E.3    Hoiby, E.A.4    Nokleby, H.5    Aaberge, I.S.6    Rosenqvist, E.7
  • 26
    • 14844296966 scopus 로고    scopus 로고
    • MeNZB: A safe and highly immunogenic tailor-made vaccine against the New Zealand Neisseria meningitidis serogroup B disease epidemic strain
    • DOI 10.1016/j.vaccine.2005.01.063
    • Oster P, Lennon D, O'Hallahan J, Mulholland K, Reid S, Martin D. MeNZB: a safe and highly immunogenic tailor-made vaccine against the New Zealand Neisseria meningitidis serogroup B disease epidemic strain. Vaccine 23(17-18), 2191-2196 (2005). • Summarizes clinical data in adults, children, toddlers and infants after immunization with the outer membrane vesicle (OMV) vaccine MeNZB™. (Pubitemid 40341449)
    • (2005) Vaccine , vol.23 , Issue.17-18 , pp. 2191-2196
    • Oster, P.1    Lennon, D.2    O'Hallahan, J.3    Mulholland, K.4    Reid, S.5    Martin, D.6
  • 27
    • 34547872096 scopus 로고    scopus 로고
    • Seroprevalence of bactericidal and anti-outer membrane vesicle antibodies to Neisseria meningitidis group B in England
    • Trotter C, Findlow J, Balmer P et al. Seroprevalence of bactericidal and anti-outer membrane vesicle antibodies to Neisseria meningitidis group B in England. Clin. Vaccine Immunol. 14(7), 863-868 (2007).
    • (2007) Clin. Vaccine Immunol. , vol.14 , Issue.7 , pp. 863-868
    • Trotter, C.1    Findlow, J.2    Balmer, P.3
  • 28
    • 38049084724 scopus 로고    scopus 로고
    • Immunity to Neisseria meningitidis group B in adults despite lack of serum bactericidal antibody
    • Welsch JA, Granoff D. Immunity to Neisseria meningitidis group B in adults despite lack of serum bactericidal antibody. Clin. Vaccine Immunol. 14(12), 1596-1602 (2007).
    • (2007) Clin. Vaccine Immunol. , vol.14 , Issue.12 , pp. 1596-1602
    • Welsch, J.A.1    Granoff, D.2
  • 30
    • 33745912508 scopus 로고    scopus 로고
    • The VR2 epitope on the PorA P1.7-2,4 protein is the major target for the immune response elicited by the strain-specific group B meningococcal vaccine MeNZB
    • DOI 10.1128/CVI.13.4.486-491.2006
    • Martin DR, Ruijne N, McCallum L, O'Hallahan J, Oster P. The VR2 epitope on the PorA P1.7-2,4 protein is the major target for the immune response elicited by the strain-specific group B meningococcal vaccine MeNZB. Clin. Vaccine Immunol. 13(4), 486-491 (2006). (Pubitemid 44044834)
    • (2006) Clinical and Vaccine Immunology , vol.13 , Issue.4 , pp. 486-491
    • Martin, D.R.1    Ruijne, N.2    McCallum, L.3    O'Hallahan, J.4    Oster, P.5
  • 31
    • 37349020019 scopus 로고    scopus 로고
    • Comparison of phenotypically indistinguishable but geographically distinct Neisseria meningitidis group B isolates in a serum bactericidal antibody assay
    • DOI 10.1128/CVI.00195-07
    • Findlow J, Holland A, Andrews N et al. Comparison of phenotypically indistinguishable but geographically distinct Neisseria meningitidis group B isolates in a serum bactericidal antibody assay. Clin. Vaccine Immunol. 14(11), 1451-1457 (2007). (Pubitemid 350304039)
    • (2007) Clinical and Vaccine Immunology , vol.14 , Issue.11 , pp. 1451-1457
    • Findlow, J.1    Holland, A.2    Andrews, N.3    Weynants, V.4    Sotolongo, F.5    Balmer, P.6    Poolman, J.7    Borrow, R.8
  • 33
    • 0001779442 scopus 로고    scopus 로고
    • Outer membrane protein vesicle vaccines for meningococcal disease
    • Pollard AJ, Maiden MC (Eds). Humana Press Inc., NJ, USA • Describes the process of OMV production, crucial to the development of many vaccines discussed in this review
    • Frasch CE, Van Alphen L, Holst J, Poolman JT, Rosenqvist E. Outer membrane protein vesicle vaccines for meningococcal disease. In: Meningococcal vaccines. Pollard AJ, Maiden MC (Eds). Humana Press Inc., NJ, USA 81-107 (2001). • Describes the process of OMV production, crucial to the development of many vaccines discussed in this review.
    • (2001) Meningococcal Vaccines , pp. 81-107
    • Frasch, C.E.1    Van Alphen, L.2    Holst, J.3    Poolman, J.T.4    Rosenqvist, E.5
  • 34
    • 0024420817 scopus 로고
    • Measurements of lipopolysaccharide (endotoxin) in meningococcal protein and polysaccharide preparations for vaccine usage
    • DOI 10.1016/0092-1157(89)90017-6
    • Tsai CM, Frasch CE, Rivera E, Hochstein HD. Measurements of lipopolysaccharide (endotoxin) in meningococcal protein and polysaccharide preparations for vaccine usage. J. Biol. Stand. 17(3), 249-258 (1989). (Pubitemid 19219369)
    • (1989) Journal of Biological Standardization , vol.17 , Issue.3 , pp. 249-258
    • Tsai, C.-M.1    Frasch, C.E.2    Rivera, E.3    Hochstein, H.D.4
  • 35
    • 23244453502 scopus 로고    scopus 로고
    • Protective antibody responses elicited by a meningococcal outer membrane vesicle vaccine with overexpressed genome-derived neisserial antigen 1870
    • DOI 10.1086/432102
    • Hou VC, Koeberling O, Welsch JA, Granoff DM. Protective antibody responses elicited by a meningococcal outer membrane vesicle vaccine with overexpressed genome-derived neisserial antigen 1870. J. Infect. Dis. 192(4), 580-590 (2005). (Pubitemid 41099306)
    • (2005) Journal of Infectious Diseases , vol.192 , Issue.4 , pp. 580-590
    • Hou, V.C.1    Koeberling, O.2    Welsch, J.A.3    Granoff, D.M.4
  • 37
    • 0031816226 scopus 로고    scopus 로고
    • Immune responses against major outer membrane antigens of Neisseria meningitidis in vaccinees and controls who contracted meningococcal disease during the Norwegian serogroup B protection trial
    • Wedege E, Hoiby EA, Rosenqvist E, Bjune G. Immune responses against major outer membrane antigens of Neisseria meningitidis in vaccinees and controls who contracted meningococcal disease during the Norwegian Serogroup B protection trial. Infect. Immun., 66(7), 3223-3231 (1998). (Pubitemid 28303120)
    • (1998) Infection and Immunity , vol.66 , Issue.7 , pp. 3223-3231
    • Wedege, E.1    Hoiby, E.A.2    Rosenqvist, E.3    Bjune, G.4
  • 38
    • 0028794029 scopus 로고
    • Antibodies to meningococcal class 1 outer-membrane protein and its variable regions in patients with systemic meningococcal disease
    • Idanpaan-Heikkila I, Hoiby EA, Chattopadhyay P, Airaksinen U, Michaelsen TM, Wedege E. Antibodies to meningococcal class 1 outer-membrane protein and its variable regions in patients with systemic meningococcal disease. J. Med. Microbiol. 43(5), 335-343 (1995).
    • (1995) J. Med. Microbiol. , vol.43 , Issue.5 , pp. 335-343
    • Idanpaan-Heikkila, I.1    Hoiby, E.A.2    Chattopadhyay, P.3    Airaksinen, U.4    Michaelsen, T.M.5    Wedege, E.6
  • 40
    • 20044392859 scopus 로고    scopus 로고
    • The concept of 'tailor-made', protein-based, outer membrane vesicle vaccines against meningococcal disease
    • Holst J, Feiring B, Naess LM et al. The concept of 'tailor-made', protein-based, outer membrane vesicle vaccines against meningococcal disease. Vaccine 23(17-18), 2202-2205 (2005).
    • (2005) Vaccine , vol.23 , Issue.17-18 , pp. 2202-2205
    • Holst, J.1    Feiring, B.2    Naess, L.M.3
  • 42
    • 35748940282 scopus 로고    scopus 로고
    • Functional and specific antibody responses in adult volunteers in New Zealand who were given one of two different meningococcal serogroup B outer membrane vesicle vaccines
    • Wedege E, Bolstad K, Aase A et al. Functional and specific antibody responses in adult volunteers in New Zealand who were given one of two different meningococcal serogroup B outer membrane vesicle vaccines. Clin. Vaccine Immunol. 14(7), 830-838 (2007).
    • (2007) Clin. Vaccine Immunol. , vol.14 , Issue.7 , pp. 830-838
    • Wedege, E.1    Bolstad, K.2    Aase, A.3
  • 43
    • 0026328249 scopus 로고
    • Results of an efficacy trial with an outer membrane vesicle vaccine against systemic serogroup B meningococcal disease in Norway
    • Bjune G, Gronnesby JK, Hoiby EA, Closs O, Nokleby H. Results of an efficacy trial with an outer membrane vesicle vaccine against systemic serogroup B meningococcal disease in Norway. NIPH Ann. 14(2), 125-130 (1991).
    • (1991) NIPH Ann. , vol.14 , Issue.2 , pp. 125-130
    • Bjune, G.1    Gronnesby, J.K.2    Hoiby, E.A.3    Closs, O.4    Nokleby, H.5
  • 45
    • 0026334477 scopus 로고
    • Vaccine against group B Neisseria meningitidis: Protection trial and mass vaccination results in Cuba
    • Sierra GV, Campa HC, Varcacel NM et al. Vaccine against group B Neisseria meningitidis: protection trial and mass vaccination results in Cuba. NIPH Ann. 14(2), 195-207 (1991).
    • (1991) NIPH Ann. , vol.14 , Issue.2 , pp. 195-207
    • Sierra, G.V.1    Campa, H.C.2    Varcacel, N.M.3
  • 47
    • 0026730501 scopus 로고
    • Protective efficacy of a serogroup B meningococcal vaccine in Sao Paulo, Brazil
    • de Moraes JC, Perkins BA, Camargo MC et al. Protective efficacy of a serogroup B meningococcal vaccine in Sao Paulo, Brazil. Lancet 340(8827), 1074-1078 (1992).
    • (1992) Lancet , vol.340 , Issue.8827 , pp. 1074-1078
    • De Moraes, J.C.1    Perkins, B.A.2    Camargo, M.C.3
  • 48
    • 0028972957 scopus 로고
    • Assessment of the direct effectiveness of BC meningococcal vaccine in Rio de Janeiro, Brazil: A case-control study
    • Noronha CP, Struchiner CJ, Halloran ME. Assessment of the direct effectiveness of BC meningococcal vaccine in Rio de Janeiro, Brazil: a case-control study. Int. J. Epidemiol. 24(5), 1050-1057 (1995). (Pubitemid 26466129)
    • (1995) International Journal of Epidemiology , vol.24 , Issue.5 , pp. 1050-1057
    • Noronha, C.P.1    Struchiner, C.J.2    Halloran, M.E.3
  • 50
    • 0028788521 scopus 로고
    • Human antibody responses to meningococcal outer membrane antigens after three doses of the Norwegian group B meningococcal vaccine
    • Rosenqvist E, Hoiby EA, Wedege E et al. Human antibody responses to meningococcal outer membrane antigens after three doses of the Norwegian group B meningococcal vaccine. Infect. Immun. 63(12), 4642-4652 (1995).
    • (1995) Infect. Immun. , vol.63 , Issue.12 , pp. 4642-4652
    • Rosenqvist, E.1    Hoiby, E.A.2    Wedege, E.3
  • 51
    • 1042309227 scopus 로고    scopus 로고
    • A 'tailor made' vaccine trialled as part of public health response to group B meningococcal epidemic in New Zealand
    • Holst J, Aaberge I, Oster P et al. A 'tailor made' vaccine trialled as part of public health response to group B meningococcal epidemic in New Zealand. Eurosurveillance 7(30) (2003)
    • (2003) Eurosurveillance , vol.7 , Issue.30
    • Holst, J.1    Aaberge, I.2    Oster, P.3
  • 55
    • 33947575120 scopus 로고    scopus 로고
    • Immunogenicity and safety of a strain-specific MenB OMV vaccine delivered to under 5-year olds in New Zealand
    • DOI 10.1016/j.vaccine.2007.01.023, PII S0264410X07000448
    • Oster P, O'Hallahan J, Aaberge I, Tilman S, Ypma E, Martin D. Immunogenicity and safety of a strain-specific MenB OMV vaccine delivered to under 5-year olds in New Zealand. Vaccine 25(16), 3075-3079 (2007). (Pubitemid 46482737)
    • (2007) Vaccine , vol.25 , Issue.16 SPEC. ISS , pp. 3075-3079
    • Oster, P.1    O'Hallahan, J.2    Aaberge, I.3    Tilman, S.4    Ypma, E.5    Martin, D.6
  • 56
    • 34548736093 scopus 로고    scopus 로고
    • A prospective study of the effectiveness of the New Zealand meningococcal B vaccine
    • DOI 10.1093/aje/kwm147
    • Kelly C, Arnold R, Galloway Y, O'Hallahan J. A prospective study of the effectiveness of the New Zealand meningococcal B vaccine. Am. J. Epidemiol. 166(7), 817-823 (2007). (Pubitemid 47428901)
    • (2007) American Journal of Epidemiology , vol.166 , Issue.7 , pp. 817-823
    • Kelly, C.1    Arnold, R.2    Galloway, Y.3    O'Hallahan, J.4
  • 57
    • 64449083731 scopus 로고    scopus 로고
    • Use of an observational cohort study to estimate the effectiveness of the New Zealand group B meningococcal vaccine in children aged under 5 years
    • Galloway Y, Stehr-Green P, McNicholas A, O'Hallahan J. Use of an observational cohort study to estimate the effectiveness of the New Zealand group B meningococcal vaccine in children aged under 5 years. Int. J. Epidemiol. (2008).
    • (2008) Int. J. Epidemiol.
    • Galloway, Y.1    Stehr-Green, P.2    McNicholas, A.3    O'Hallahan, J.4
  • 61
    • 33947730449 scopus 로고    scopus 로고
    • Safety review: Two outer membrane vesicle (OMV) vaccines against systemic Neisseria meningitidis serogroup B disease
    • DOI 10.1016/j.vaccine.2007.01.022, PII S0264410X0700045X
    • Nokleby H, Aavitsland P, O'Hallahan J, Feiring B, Tilman S, Oster P. Safety review: two outer membrane vesicle (OMV) vaccines against systemic Neisseria meningitidis serogroup B disease. Vaccine 25(16), 3080-3084 (2007). (Pubitemid 46505045)
    • (2007) Vaccine , vol.25 , Issue.16 SPEC. ISS , pp. 3080-3084
    • Nokleby, H.1    Aavitsland, P.2    O'Hallahan, J.3    Feiring, B.4    Tilman, S.5    Oster, P.6
  • 62
    • 67049127189 scopus 로고    scopus 로고
    • Safety of meningococcal B vaccines
    • WHO
    • WHO. Safety of meningococcal B vaccines. Wkly Epidemiol. Rec. (83), 37-44 (2008).
    • (2008) Wkly Epidemiol. Rec. , Issue.83 , pp. 37-44
  • 63
    • 67049089861 scopus 로고    scopus 로고
    • Meningococcal serogroup B vaccine (MenBvac): Pharmacovigilance follow-up of the vaccination campaign in the department of Seine-Maritime (Upper-Normandy)
    • Noblet C, Cordier L, Massy N, Jacquet A, Thuillez C. Meningococcal serogroup B vaccine (MenBvac): pharmacovigilance follow-up of the vaccination campaign in the department of Seine-Maritime (Upper-Normandy). Fundam. Clin. Pharmacol. 21(s1), 7 (2007).
    • (2007) Fundam. Clin. Pharmacol. , vol.21 , Issue.S1 , pp. 7
    • Noblet, C.1    Cordier, L.2    Massy, N.3    Jacquet, A.4    Thuillez, C.5
  • 64
    • 33947142417 scopus 로고    scopus 로고
    • Use of available outer membrane vesicle vaccines to control serogroup B meningococcal outbreaks
    • DOI 10.1016/j.vaccine.2005.12.059, PII S0264410X0600003X
    • Taha MK, Zarantonelli ML, Alonso JM et al. Use of available outer membrane vesicle vaccines to control serogroup B meningococcal outbreaks. Vaccine 25(14), 2537-2538 (2007). (Pubitemid 46400920)
    • (2007) Vaccine , vol.25 , Issue.14 , pp. 2537-2538
    • Taha, M.-K.1    Zarantonelli, M.L.2    Alonso, J.-M.3    Naess, L.M.4    Holst, J.5    Feiring, B.6    Rosenqvist, E.7
  • 65
    • 0017843254 scopus 로고
    • Carriage of Neisseria meningitidis and Neisseria lactamica in infants and children
    • Gold R, Goldschneider I, Lepow ML, Draper TF, Randolph M. Carriage of Neisseria meningitidis and Neisseria lactamica in infants and children. J. Infect. Dis. 137(2), 112-121 (1978). (Pubitemid 8289151)
    • (1978) Journal of Infectious Diseases , vol.137 , Issue.2 , pp. 112-121
    • Gold, R.1    Goldschneider, I.2    Lepow, M.L.3
  • 66
    • 0023607404 scopus 로고
    • The Stonehouse survey: Nasopharyngeal carriage of meningococci and Neisseria lactamica
    • Cartwright KA, Stuart JM, Jones DM, Noah ND. The Stonehouse survey: nasopharyngeal carriage of meningococci and Neisseria lactamica. Epidemiol. Infect. 99(3), 591-601 (1987). (Pubitemid 18034332)
    • (1987) Epidemiology and Infection , vol.99 , Issue.3 , pp. 591-601
    • Cartwright, K.A.V.1    Stuart, J.M.2    Jones, D.M.3    Noah, N.D.4
  • 68
    • 33750464088 scopus 로고    scopus 로고
    • Immunization with live Neisseria lactamica protects mice against meningococcal challenge and can elicit serum bactericidal antibodies
    • DOI 10.1128/IAI.01062-06
    • Li Y, Zhang Q, Winterbotham M, Mowe E, Gorringe A, Tang CM. Immunization with live Neisseria lactamica protects mice against meningococcal challenge and can elicit serum bactericidal antibodies. Infect. Immun. 74(11), 6348-6355 (2006). (Pubitemid 44657417)
    • (2006) Infection and Immunity , vol.74 , Issue.11 , pp. 6348-6355
    • Li, Y.1    Zhang, Q.2    Winterbotham, M.3    Mowe, E.4    Gorringe, A.5    Tang, C.M.6
  • 73
    • 0030663502 scopus 로고    scopus 로고
    • Analysis of the human Ig isotype response to individual transferrin binding proteins a and B from Neisseria meningitidis
    • DOI 10.1016/S0928-8244(97)00082-5, PII S0928824497000825
    • Johnson AS, Gorringe AR, Fox AJ, Borrow R, Robinson A. Analysis of the human Ig isotype response to individual transferrin binding proteins A and B from Neisseria meningitidis. FEMS Immunol. Med. Microbiol. 19(2), 159-167 (1997). (Pubitemid 27467069)
    • (1997) FEMS Immunology and Medical Microbiology , vol.19 , Issue.2 , pp. 159-167
    • Johnson, A.S.1    Gorringe, A.R.2    Fox, A.J.3    Borrow, R.4    Robinson, A.5
  • 74
    • 0027252119 scopus 로고
    • Preparation and analysis of isogenic mutants in the transferrin receptor protein genes, tbpA and tbpB, from Neisseria meningitidis
    • Irwin SW, Averil N, Cheng CY, Schryvers AB. Preparation and analysis of isogenic mutants in the transferrin receptor protein genes, tbpA and tbpB, from Neisseria meningitidis. Mol. Microbiol. 8(6), 1125-1133 (1993). (Pubitemid 23187031)
    • (1993) Molecular Microbiology , vol.8 , Issue.6 , pp. 1125-1133
    • Irwin, S.W.1    Averil, N.2    Cheng, C.Y.3    Schryvers, A.B.4
  • 75
    • 0027229173 scopus 로고
    • Expression of gonococcal transferrin-binding protein 1 causes Escherichia coli to bind human transferrin
    • Cornelissen CN, Biswas GD, Sparling PF. Expression of gonococcal transferrin-binding protein 1 causes Escherichia coli to bind human transferrin. J. Bacteriol. 175(8), 2448-2450 (1993). (Pubitemid 23123522)
    • (1993) Journal of Bacteriology , vol.175 , Issue.8 , pp. 2448-2450
    • Cornelissen, C.N.1    Biswas, G.D.2    Sparling, P.F.3
  • 76
    • 0029894182 scopus 로고    scopus 로고
    • Bacterial transferrin and lactoferrin receptors
    • DOI 10.1016/0966-842X(96)10025-1
    • Gray-Owen SD, Schryvers AB. Bacterial transferrin and lactoferrin receptors. Trends Microbiol. 4(5), 185-191 (1996). (Pubitemid 26162132)
    • (1996) Trends in Microbiology , vol.4 , Issue.5 , pp. 185-191
    • Gray-Owen, S.D.1    Schryvers, A.B.2
  • 77
    • 0027378504 scopus 로고
    • Transferrin-binding proteins isolated fron Neisseria meningitidis elicit protective and bactericidal antibodies in laboratory animals
    • DOI 10.1016/0264-410X(93)90045-Y
    • Danve B, Lissolo L, Mignon M et al. Transferrin-binding proteins isolated from Neisseria meningitidis elicit protective and bactericidal antibodies in laboratory animals. Vaccine 11(12), 1214-1220 (1993). (Pubitemid 23308778)
    • (1993) Vaccine , vol.11 , Issue.12 , pp. 1214-1220
    • Danve, B.1    Lissolo, L.2    Mignon, M.3    Dumas, P.4    Colombani, S.5    Schryvers, A.B.6    Quentin-Millet, M.-J.7
  • 78
    • 0028935214 scopus 로고
    • Evaluation of transferrin-binding protein 2 within the transferrin-binding protein complex as a potential antigen for future meningococcal vaccines
    • Lissolo L, Maitre-Wilmotte G, Dumas P, Mignon M, Danve B, Quentin-Millet MJ. Evaluation of transferrin-binding protein 2 within the transferrin-binding protein complex as a potential antigen for future meningococcal vaccines. Infect. Immun. 63(3), 884-890 (1995).
    • (1995) Infect. Immun. , vol.63 , Issue.3 , pp. 884-890
    • Lissolo, L.1    Maitre-Wilmotte, G.2    Dumas, P.3    Mignon, M.4    Danve, B.5    Quentin-Millet, M.J.6
  • 79
    • 0027233438 scopus 로고
    • Identification of two major families of transferrin receptors among Neisseria meningitidis strains based on antigenic and genomic features
    • DOI 10.1016/0378-1097(93)90241-S
    • Rokbi B, Mazarin V, Maitre-Wilmotte G, Quentin-Millet MJ. Identification of two major families of transferrin receptors among Neisseria meningitidis strains based on antigenic and genomic features. FEMS Microbiol. Lett. 110(1), 51-57 (1993). (Pubitemid 23171227)
    • (1993) FEMS Microbiology Letters , vol.110 , Issue.1 , pp. 51-58
    • Rokbi, B.1    Mazarin, V.2    Maitre-Wilmotte, G.3    Quentin-Millet, M.-J.4
  • 80
    • 0030770711 scopus 로고    scopus 로고
    • Heterogeneity of tbpB, the transferrin-binding protein B gene, among serogroup B Neisseria meningitidis strains of the ET-5 complex
    • Rokbi B, Mignon M, Caugant DA, Quentin-Millet MJ. Heterogeneity of tbpB, the transferrin-binding protein B gene, among serogroup B Neisseria meningitidis strains of the ET-5 complex. Clin. Diagn. Lab. Immunol. 4(5), 522-529 (1997). (Pubitemid 27448616)
    • (1997) Clinical and Diagnostic Laboratory Immunology , vol.4 , Issue.5 , pp. 522-529
    • Rokbi, B.1    Mignon, M.2    Caugant, D.A.3    Quentin-Millet, M.J.4
  • 82
    • 0027524614 scopus 로고
    • Meningococcal Opa and Opc proteins: Their role in colonization and invasion of human epithelial and endothelial cells
    • DOI 10.1111/j.1365-2958.1993.tb00922.x
    • Virji M, Makepeace K, Ferguson DJ, Achtman M, Moxon ER. Meningococcal Opa and Opc proteins: their role in colonization and invasion of human epithelial and endothelial cells. Mol. Microbiol. 10(3), 499-510 (1993). (Pubitemid 23334431)
    • (1993) Molecular Microbiology , vol.10 , Issue.3 , pp. 499-510
    • Virji, M.1    Makepeace, K.2    Ferguson, D.J.P.3    Achtman, M.4    Moxon, E.R.5
  • 83
    • 33748074140 scopus 로고    scopus 로고
    • Opacity-associated adhesin repertoire in hyperinvasive Neisseria meningitidis
    • DOI 10.1128/IAI.00293-06
    • Callaghan MJ, Jolley KA, Maiden MC. Opacity-associated adhesin repertoire in hyperinvasive Neisseria meningitidis. Infect. Immun. 74(9), 5085-5094 (2006). (Pubitemid 44300426)
    • (2006) Infection and Immunity , vol.74 , Issue.9 , pp. 5085-5094
    • Callaghan, M.J.1    Jolley, K.A.2    Maiden, M.C.J.3
  • 88
    • 0030951492 scopus 로고    scopus 로고
    • Highly conserved Neisseria meningitidis surface protein confers protection against experimental infection
    • DOI 10.1084/jem.185.7.1173
    • Martin D, Cadieux N, Hamel J, Brodeur BR. Highly conserved Neisseria meningitidis surface protein confers protection against experimental infection. J. Exp. Med. 185(7), 1173-1183 (1997). (Pubitemid 27172898)
    • (1997) Journal of Experimental Medicine , vol.185 , Issue.7 , pp. 1173-1183
    • Martin, D.1    Cadieux, N.2    Hamel, J.3    Brodeur, B.R.4
  • 89
    • 0032797585 scopus 로고    scopus 로고
    • Bactericidal and cross-protective activities of a monoclonal antibody directed against Neisseria meningitidis NspA outer membrane protein
    • Cadieux N, Plante M, Rioux CR, Hamel J, Brodeur BR, Martin D. Bactericidal and cross-protective activities of a monoclonal antibody directed against Neisseria meningitidis NspA outer membrane protein. Infect. Immun. 67(9), 4955-4959 (1999). (Pubitemid 29400491)
    • (1999) Infection and Immunity , vol.67 , Issue.9 , pp. 4955-4959
    • Cadieux, N.1    Plante, M.2    Rioux, C.R.3    Hamel, J.4    Brodeur, B.R.5    Martin, D.6
  • 90
    • 0034730705 scopus 로고    scopus 로고
    • Candidate Neisseria meningitidis NspA vaccine
    • Martin D, Brodeur BR, Hamel J et al. Candidate Neisseria meningitidis NspA vaccine. J. Biotechnol. 83(1-2), 27-31 (2000).
    • (2000) J. Biotechnol. , vol.83 , Issue.1-2 , pp. 27-31
    • Martin, D.1    Brodeur, B.R.2    Hamel, J.3
  • 91
    • 33845201825 scopus 로고    scopus 로고
    • Phase 1 first-in-human studies of the reactogenicity and immunogenicity of a recombinant meningococcal NspA vaccine in healthy adults
    • DOI 10.1016/j.vaccine.2006.08.001, PII S0264410X06009297
    • Halperin SA, Langley JM, Smith B et al. Phase 1 first-in-human studies of the reactogenicity and immunogenicity of a recombinant meningococcal NspA vaccine in healthy adults. Vaccine 25(3), 450-457 (2007). (Pubitemid 44856095)
    • (2007) Vaccine , vol.25 , Issue.3 , pp. 450-457
    • Halperin, S.A.1    Langley, J.M.2    Smith, B.3    Wunderli, P.4    Kaufman, L.5    Kimura, A.6    Martin, D.7
  • 92
    • 0032706010 scopus 로고    scopus 로고
    • Differences in surface expression of NspA among Neisseria meningitidis group B strains
    • Moe GR, Tan S, Granoff DM. Differences in surface expression of NspA among Neisseria meningitidis group B strains. Infect. Immun. 67(11), 5664-5675 (1999). (Pubitemid 29508084)
    • (1999) Infection and Immunity , vol.67 , Issue.11 , pp. 5664-5675
    • Moe, G.R.1    Tan, S.2    Granoff, D.M.3
  • 94
    • 58149199760 scopus 로고    scopus 로고
    • Naturally-occurring human serum antibodies to inner core lipopolysaccharide epitopes of Neisseria meningitidis protect against invasive meningococcal disease caused by isolates displaying homologous inner core structures
    • Jakel A, Plested JS, Hoe JC et al. Naturally-occurring human serum antibodies to inner core lipopolysaccharide epitopes of Neisseria meningitidis protect against invasive meningococcal disease caused by isolates displaying homologous inner core structures. Vaccine 26(51), 6655-6663 (2008).
    • (2008) Vaccine , vol.26 , Issue.51 , pp. 6655-6663
    • Jakel, A.1    Plested, J.S.2    Hoe, J.C.3
  • 95
    • 0021241866 scopus 로고
    • Immune response of infants and children to disseminated infections with Neisseria meningitidis
    • Griffiss JM, Brandt BL, Broud DD, Goroff DK, Baker CJ. Immune response of infants and children to disseminated infections with Neisseria meningitidis. J. Infect. Dis. 150(1), 71-79 (1984). (Pubitemid 14093836)
    • (1984) Journal of Infectious Diseases , vol.150 , Issue.1 , pp. 71-79
    • McLeod Griffiss, J.1    Brandt, B.L.2    Broud, D.D.3
  • 97
    • 0033588487 scopus 로고    scopus 로고
    • Safety and immunogenicity testing of an intranasal group B meningococcal native outer membrane vesicle vaccine in healthy volunteers
    • DOI 10.1016/S0264-410X(99)00216-9, PII S0264410X99002169
    • Drabick JJ, Brandt BL, Moran EE, Saunders NB, Shoemaker DR, Zollinger WD. Safety and immunogenicity testing of an intranasal group B meningococcal native outer membrane vesicle vaccine in healthy volunteers. Vaccine 18(1-2), 160-172 (1999). (Pubitemid 29432149)
    • (1999) Vaccine , vol.18 , Issue.1-2 , pp. 160-172
    • Drabick, J.J.1    Brandt, B.L.2    Moran, E.E.3    Saunders, N.B.4    Shoemaker, D.R.5    Zollinger, W.D.6
  • 98
    • 0024986143 scopus 로고
    • Polysaccharides and membrane vaccines
    • Mizrahi A (Ed.). John Wiley and Sons Ltd, New York, USA
    • Poolman JT. Polysaccharides and membrane vaccines. In: Bacterial Vaccines. Mizrahi A (Ed.). John Wiley and Sons Ltd, New York, USA, 57-86 (1990).
    • (1990) Bacterial Vaccines , pp. 57-86
    • Poolman, J.T.1
  • 99
    • 0025951590 scopus 로고
    • Eight lipooligosaccharides of Neisseria meningitidis react with a monoclonal antibody which binds lacto-N-neotetraose (Gal β 1-4GlcNAc β 1-3Gal β 1-4Glc)
    • Tsai CM, Civin CI. Eight lipooligosaccharides of Neisseria meningitidis react with a monoclonal antibody which binds lacto-N-neotetraose (Gal β 1-4GlcNAc β 1-3Gal β 1-4Glc). Infect. Immun. 59(10), 3604-3609 (1991).
    • (1991) Infect. Immun. , vol.59 , Issue.10 , pp. 3604-3609
    • Tsai, C.M.1    Civin, C.I.2
  • 101
    • 0038288987 scopus 로고    scopus 로고
    • Lesson from an LPS-deficient Neisseria meningitidis mutant
    • DOI 10.1179/096805103125001522
    • van der Ley P, Steeghs L. Lessons from an LPS-deficient Neisseria meningitidis mutant. J. Endotoxin Res. 9(2), 124-128 (2003). (Pubitemid 36603688)
    • (2003) Journal of Endotoxin Research , vol.9 , Issue.2 , pp. 124-128
    • Van Der Ley, P.1    Steeghs, L.2
  • 102
    • 67049168681 scopus 로고
    • Phase I safety and immunogenicity study of a meningococcal outer membrane protein, detoxified LPS vaccine
    • Presented at: Hanasaari, Finland, 9-11 September
    • Zollinger WD, Moran EE, Ray J, McClain B. Phase I safety and immunogenicity study of a meningococcal outer membrane protein, detoxified LPS vaccine. Presented at: Frontiers in Vaccine Research. Hanasaari, Finland, 9-11 September 1991.
    • (1991) Frontiers in Vaccine Research
    • Zollinger, W.D.1    Moran, E.E.2    Ray, J.3    McClain, B.4
  • 107
    • 0035925596 scopus 로고    scopus 로고
    • Reverse vaccinology, a genome-based approach to vaccine development
    • DOI 10.1016/S0264-410X(00)00554-5, PII S0264410X00005545
    • Rappuoli R. Reverse vaccinology, a genome-based approach to vaccine development. Vaccine 19(17-19), 2688-2691 (2001). (Pubitemid 32234290)
    • (2001) Vaccine , vol.19 , Issue.17-19 , pp. 2688-2691
    • Rappuoli, R.1
  • 108
    • 0034629284 scopus 로고    scopus 로고
    • Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing
    • Pizza M, Scarlato V, Masignani V et al. Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing. Science 287(5459), 1816-1820 (2000).
    • (2000) Science , vol.287 , Issue.5459 , pp. 1816-1820
    • Pizza, M.1    Scarlato, V.2    Masignani, V.3
  • 110
    • 46249125662 scopus 로고    scopus 로고
    • Specificity of the sub-capsular antibody responses following serogroup a meningococcal disease in Ethiopian patients
    • Norheim G, Aseffa A, Yassin MA et al. Specificity of the sub-capsular antibody responses following serogroup A meningococcal disease in Ethiopian patients. Clin. Vaccine Immunol. 15(5), 863-871 (2008).
    • (2008) Clin. Vaccine Immunol. , vol.15 , Issue.5 , pp. 863-871
    • Norheim, G.1    Aseffa, A.2    Yassin, M.A.3
  • 111
    • 3042681606 scopus 로고    scopus 로고
    • Mucosal vaccination against serogroup B meningococci: Induction of bactericidal antibodies and cellular immunity following intranasal immunization with NadA of Neisseria meningitidis and mutants of Escherichia coli heat-labile enterotoxin
    • DOI 10.1128/IAI.72.7.4052-4060.2004
    • Bowe F, Lavelle EC, McNeela EA et al. Mucosal vaccination against serogroup B meningococci: induction of bactericidal antibodies and cellular immunity following intranasal immunization with NadA of Neisseria meningitidis and mutants of Escherichia coli heat-labile enterotoxin. Infect. Immun. 72(7), 4052-4060 (2004). (Pubitemid 38821920)
    • (2004) Infection and Immunity , vol.72 , Issue.7 , pp. 4052-4060
    • Bowe, F.1    Lavelle, E.C.2    McNeela, E.A.3    Hale, C.4    Clare, S.5    Arico, B.6    Giuliani, M.M.7    Rae, A.8    Huett, A.9    Rappuoli, R.10    Dougan, G.11    Mills, K.H.G.12
  • 112
    • 47149091261 scopus 로고    scopus 로고
    • Intranasal immunization of mice with recombinant Streptococcus gordonii expressing NadA of Neisseria meningitidis induces systemic bactericidal antibodies and local IgA
    • Ciabattini A, Giomarelli B, Parigi R et al. Intranasal immunization of mice with recombinant Streptococcus gordonii expressing NadA of Neisseria meningitidis induces systemic bactericidal antibodies and local IgA. Vaccine 26(33), 4244-4250 (2008).
    • (2008) Vaccine , vol.26 , Issue.33 , pp. 4244-4250
    • Ciabattini, A.1    Giomarelli, B.2    Parigi, R.3
  • 113
    • 34248166509 scopus 로고    scopus 로고
    • Prevalence of factor H-binding protein variants and NadA among meningococcal group B isolates from the United States: Implications for the development of a multicomponent group B vaccine
    • DOI 10.1086/514821
    • Beernink PT, Welsch JA, Harrison LH, Leipus A, Kaplan SL, Granoff DM. Prevalence of factor H-binding protein variants and NadA among meningococcal group B isolates from the United States: implications for the development of a multicomponent group B vaccine. J. Infect. Dis. 195(10), 1472-1479 (2007). (Pubitemid 46717465)
    • (2007) Journal of Infectious Diseases , vol.195 , Issue.10 , pp. 1472-1479
    • Beernink, P.T.1    Welsch, J.A.2    Harrison, L.H.3    Leipus, A.4    Kaplan, S.L.5    Granoff, D.M.6
  • 115
    • 0023000103 scopus 로고
    • A synthetic analogue of Escherichia coli lipoprotein, tripalmitoyl pentapeptide, constitutes a potent immune adjuvant
    • Lex A, Wiesmuller KH, Jung G, Bessler WG. A synthetic analogue of Escherichia coli lipoprotein, tripalmitoyl pentapeptide, constitutes a potent immune adjuvant. J. Immunol. 137(8), 2676-2681 (1986). (Pubitemid 17176628)
    • (1986) Journal of Immunology , vol.137 , Issue.8 , pp. 2676-2681
    • Lex, A.1    Wiesmuller, K.H.2    Jung, G.3    Bessler, W.G.4
  • 118
    • 33744789184 scopus 로고    scopus 로고
    • Intranasal immunization of mice with recombinant lipidated P2086 protein reduces nasal colonization of group B Neisseria meningitidis
    • DOI 10.1016/j.vaccine.2006.03.051, PII S0264410X06003719
    • Zhu D, Barniak V, Zhang Y, Green B, Zlotnick G. Intranasal immunization of mice with recombinant lipidated P2086 protein reduces nasal colonization of group B Neisseria meningitidis. Vaccine 24(26), 5420-5425 (2006). (Pubitemid 43831373)
    • (2006) Vaccine , vol.24 , Issue.26 , pp. 5420-5425
    • Zhu, D.1    Barniak, V.2    Zhang, Y.3    Green, B.4    Zlotnick, G.5
  • 119
    • 25444523998 scopus 로고    scopus 로고
    • Evaluation of recombinant lipidated P2086 protein as a vaccine candidate for group B Neisseria meningitidis in a murine nasal challenge model
    • DOI 10.1128/IAI.73.10.6838-6845.2005
    • Zhu D, Zhang Y, Barniak V, Bernfield L, Howell A, Zlotnick G. Evaluation of recombinant lipidated P2086 protein as a vaccine candidate for group B Neisseria meningitidis in a murine nasal challenge model. Infect. Immun. 73(10), 6838-6845 (2005). (Pubitemid 41368851)
    • (2005) Infection and Immunity , vol.73 , Issue.10 , pp. 6838-6845
    • Zhu, D.1    Zhang, Y.2    Barniak, V.3    Bernfield, L.4    Howell, A.5    Zlotnick, G.6
  • 122
    • 67049086089 scopus 로고    scopus 로고
    • Prediction of broad vaccine coverage for a bivalent rLP2086 based vaccine which elicits serum bactericidal activity against a diverse collection of serogroup B Meningococci
    • Presented at
    • Jiang HQ, Harris SL, Tan C et al. Prediction of broad vaccine coverage for a bivalent rLP2086 based vaccine which elicits serum bactericidal activity against a diverse collection of serogroup B Meningococci. Presented at: International Pathogenic Neisseria Conference. Rotterdam, The Netherlands, 7-12 September 2008.
    • International Pathogenic Neisseria Conference. Rotterdam, the Netherlands, 7-12 September 2008
    • Jiang, H.Q.1    Harris, S.L.2    Tan, C.3
  • 126
    • 2142828652 scopus 로고    scopus 로고
    • Protective activity of monoclonal antibodies to genome-derived neisserial antigen 1870, a Neisseria meningitidis candidate vaccine
    • Welsch JA, Rossi R, Comanducci M, Granoff DM. Protective activity of monoclonal antibodies to genome-derived neisserial antigen 1870, a Neisseria meningitidis candidate vaccine. J. Immunol. 172(9), 5606-5615 (2004).
    • (2004) J. Immunol. , vol.172 , Issue.9 , pp. 5606-5615
    • Welsch, J.A.1    Rossi, R.2    Comanducci, M.3    Granoff, D.M.4
  • 127
    • 42549122663 scopus 로고    scopus 로고
    • Complement-dependent synergistic bactericidal activity of antibodies against factor H-binding protein, a sparsely distributed meningococcal vaccine antigen
    • Welsch JA, Ram S, Koeberling O, Granoff DM. Complement-dependent synergistic bactericidal activity of antibodies against factor H-binding protein, a sparsely distributed meningococcal vaccine antigen. J. Infect. Dis. 197(7), 1053-1061 (2008).
    • (2008) J. Infect. Dis. , vol.197 , Issue.7 , pp. 1053-1061
    • Welsch, J.A.1    Ram, S.2    Koeberling, O.3    Granoff, D.M.4
  • 128
    • 58449121716 scopus 로고    scopus 로고
    • Factor H-binding protein is important for meningococcal survival in human whole blood and serum and in the presence of the antimicrobial peptide LL-37
    • Seib KL, Serruto D, Oriente F et al. Factor H-binding protein is important for meningococcal survival in human whole blood and serum and in the presence of the antimicrobial peptide LL-37. Infect. Immun. 77(1), 292-299 (2009).
    • (2009) Infect. Immun. , vol.77 , Issue.1 , pp. 292-299
    • Seib, K.L.1    Serruto, D.2    Oriente, F.3
  • 132
    • 0346256759 scopus 로고    scopus 로고
    • Antibody to Genome-Derived Neisserial Antigen 2132, a Neisseria meningitidis Candidate Vaccine, Confers Protection against Bacteremia in the Absence of Complement-Mediated Bactericidal Activity
    • DOI 10.1086/379375
    • Welsch JA, Moe GR, Rossi R, Adu-Bobie J, Rappuoli R, Granoff DM. Antibody to genome-derived neisserial antigen 2132, a Neisseria meningitidis candidate vaccine, confers protection against bacteremia in the absence of complement-mediated bactericidal activity. J. Infect. Dis. 188(11), 1730-1740 (2003). (Pubitemid 38010685)
    • (2003) Journal of Infectious Diseases , vol.188 , Issue.11 , pp. 1730-1740
    • Welsch, J.A.1    Moe, G.R.2    Rossi, R.3    Adu-Bobie, J.4    Rappuoli, R.5    Granoff, D.M.6
  • 133
    • 0034623975 scopus 로고    scopus 로고
    • h,4 meningococcal outer membrane vesicle vaccine in toddlers: Comparison of two vaccination schedules and two vaccine formulations
    • DOI 10.1016/S0264-410X(00)00320-0, PII S0264410X00003200
    • de Kleijn ED, de Groot R, Lafeber AB et al. Immunogenicity and safety of monovalent p1.7(h),4 meningococcal outer membrane vesicle vaccine in toddlers: comparison of two vaccination schedules and two vaccine formulations. Vaccine 19(9-10), 1141-1148 (2000). (Pubitemid 32008280)
    • (2000) Vaccine , vol.19 , Issue.9-10 , pp. 1141-1148
    • De Kleijn, E.D.1    De Groot, R.2    Lafeber, A.B.3    Labadie, J.4    Van Limpt, K.C.J.P.5    Visser, J.6    Berbers, G.A.M.7    Van Alphen, L.8    Rumke, H.C.9
  • 135
    • 33847684722 scopus 로고    scopus 로고
    • Immunogenicity of a combination vaccine containing pneumococcal conjugates and meningococcal PorA OMVs
    • DOI 10.1016/j.vaccine.2006.09.025, PII S0264410X06010279, 5TH INTERNATIONAL SYMPOSIUM ON PNEUMOCOCCI AND PNEUMOCOCCAL DISEASES
    • van den Dobbelsteen GP, van Dijken HH, Pillai S, van Alphen L. Immunogenicity of a combination vaccine containing pneumococcal conjugates and meningococcal PorA OMVs. Vaccine 25(13), 2491-2496 (2007). (Pubitemid 46366130)
    • (2007) Vaccine , vol.25 , Issue.13 , pp. 2491-2496
    • Van Den Dobbelsteen, G.P.J.M.1    Van Dijken, H.H.2    Pillai, S.3    Van Alphen, L.4
  • 136
    • 0023933632 scopus 로고
    • Neisseria meningitidis group B serosubtyping using monoclonal antibodies in whole-cell Elisa
    • DOI 10.1016/0882-4010(88)90045-9
    • Abdillahi H, Poolman JT. Neisseria meningitidis group B serosubtyping using monoclonal antibodies in whole-cell ELISA. Microb. Pathog. 4(1), 27-32 (1988). (Pubitemid 18103739)
    • (1988) Microbial Pathogenesis , vol.4 , Issue.1 , pp. 27-32
    • Abdillahi, H.1    Poolman, J.T.2
  • 137
    • 0033831758 scopus 로고    scopus 로고
    • Distribution of Neisseria meningitidis serogroup B serosubtypes and serotypes circulating in the United States. the Active Bacterial Core Surveillance Team
    • Tondella ML, Popovic T, Rosenstein NE et al. Distribution of Neisseria meningitidis serogroup B serosubtypes and serotypes circulating in the United States. The Active Bacterial Core Surveillance Team. J. Clin. Microbiol. 38(9), 3323-3328 (2000).
    • (2000) J. Clin. Microbiol. , vol.38 , Issue.9 , pp. 3323-3328
    • Tondella, M.L.1    Popovic, T.2    Rosenstein, N.E.3
  • 138
    • 0028938010 scopus 로고
    • Construction of Neisseria meningitidis strains carrying multiple chromosomal copies of the porA gene for use in the production of a multivalent outer membrane vesicle vaccine
    • van der Ley P, van der Biezen J, Poolman JT. Construction of Neisseria meningitidis strains carrying multiple chromosomal copies of the porA gene for use in the production of a multivalent outer membrane vesicle vaccine. Vaccine 13(4), 401-407 (1995).
    • (1995) Vaccine , vol.13 , Issue.4 , pp. 401-407
    • Van Der Ley, P.1    Van Der Biezen, J.2    Poolman, J.T.3
  • 139
    • 0033523057 scopus 로고    scopus 로고
    • Immunogenicity and reactogenicity in UK infants of a novel meningococcal vesicle vaccine containing multiple class 1 (PorA) outer membrane proteins
    • DOI 10.1016/S0264-410X(99)00044-4, PII S0264410X99000444
    • Cartwright K, Morris R, Rumke H et al. Immunogenicity and reactogenicity in UK infants of a novel meningococcal vesicle vaccine containing multiple class 1 (PorA) outer membrane proteins. Vaccine 17(20-21), 2612-2619 (1999). (Pubitemid 29314456)
    • (1999) Vaccine , vol.17 , Issue.20-21 , pp. 2612-2619
    • Cartwright, K.1    Morris, R.2    Rumke, H.3    Fox, A.4    Ray, B.5    Begg, N.6    Richmond, P.7    Poolman, J.8
  • 142
    • 32544440140 scopus 로고    scopus 로고
    • Heterologous prime-boost strategy to overcome weak immunogenicity of two serosubtypes in hexavalent Neisseria meningitidis outer membrane vesicle vaccine
    • DOI 10.1016/j.vaccine.2005.10.003, PII S0264410X0501039X
    • Luijkx T, van Dijken H, van Els C, van den Dobbelsteen G. Heterologous prime-boost strategy to overcome weak immunogenicity of two serosubtypes in hexavalent Neisseria meningitidis outer membrane vesicle vaccine. Vaccine 24(10), 1569-1577 (2006). (Pubitemid 43238232)
    • (2006) Vaccine , vol.24 , Issue.10 , pp. 1569-1577
    • Luijkx, T.1    Dijken, H.V.2    Els, C.V.3    Dobbelsteen, G.V.D.4
  • 143
    • 34247860999 scopus 로고    scopus 로고
    • Immunogenicity and safety of three doses of a bivalent (B:4:p1.19,15 and B:4:p1.7-2,4) meningococcal outer membrane vesicle vaccine in healthy adolescents
    • Boutriau D, Poolman J, Borrow R et al. Immunogenicity and safety of three doses of a bivalent (B:4:p1.19,15 and B:4:p1.7-2,4) meningococcal outer membrane vesicle vaccine in healthy adolescents. Clin. Vaccine Immunol. 14(1), 65-73 (2007).
    • (2007) Clin. Vaccine Immunol. , vol.14 , Issue.1 , pp. 65-73
    • Boutriau, D.1    Poolman, J.2    Borrow, R.3
  • 147
    • 0036156090 scopus 로고    scopus 로고
    • Immunogenicity and safety testing of a group B intranasal meningococcal native outer membrane vesicle vaccine
    • DOI 10.1128/IAI.70.2.702-707.2002
    • Katial RK, Brandt BL, Moran EE, Marks S, Agnello V, Zollinger WD. Immunogenicity and safety testing of a group B intranasal meningococcal native outer membrane vesicle vaccine. Infect. Immun. 70(2), 702-707 (2002). (Pubitemid 34083831)
    • (2002) Infection and Immunity , vol.70 , Issue.2 , pp. 702-707
    • Katial, R.K.1    Brandt, B.L.2    Moran, E.E.3    Marks, S.4    Agnello, V.5    Zollinger, W.D.6
  • 148
    • 21544435705 scopus 로고    scopus 로고
    • Characterization of native outer membrane vesicles from lpxL mutant strains of Neisseria meningitidis for use in parenteral vaccination
    • DOI 10.1128/IAI.73.7.4070-4080.2005
    • Fisseha M, Chen P, Brandt B, Kijek T, Moran E, Zollinger W. Characterization of native outer membrane vesicles from lpxL mutant strains of Neisseria meningitidis for use in parenteral vaccination. Infect. Immun. 73(7), 4070-4080 (2005). (Pubitemid 40923147)
    • (2005) Infection and Immunity , vol.73 , Issue.7 , pp. 4070-4080
    • Fisseha, M.1    Chen, P.2    Brandt, B.3    Kijek, T.4    Moran, E.5    Zollinger, W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.