Preclinical evaluation of group B Neisseria meningitidis and Escherichia coli K92 capsular polysaccharide-protein conjugate vaccines in juvenile rhesus monkeys

Infection and Immunity

Volumn 65, Issue 3, 1997, Pages 1045-1052

  Devi, Sarvamangala J N ^a   Zollinger, Wendell D ^b   Snoy, Phil J ^c   Tai, Joseph Y ^d   Costantini, Paolo ^e   Norelli, Francesco ^e   Rappuoli, Rino ^e   Frasch, Carl E ^a,c  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^c CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^d North American Vaccine Inc   (United States)

^e CHIRON VACCINES   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL POLYSACCHARIDE; BACTERIAL PROTEIN; IMMUNOLOGICAL ADJUVANT; MEMBRANE PROTEIN; MENINGOCOCCUS VACCINE;

ADOLESCENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; DRUG SAFETY; ESCHERICHIA COLI; FEMALE; IMMUNIZATION; IMMUNOGENICITY; INTRAMUSCULAR DRUG ADMINISTRATION; MALE; MENINGITIS; NEISSERIA MENINGITIDIS; NONHUMAN; PRIORITY JOURNAL; RHESUS MONKEY; SEPTICEMIA; VACCINE PRODUCTION;

EID: 0031029970     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.3.1045-1052.1997     Document Type: Article

References (46)

1. Adlam, C., J. M. Knights, A. Mugridge, J. M. Williams, and J. C. Lindon. 1987. Production of colominic acid by Pasteurella haemolytica serotype A2 organisms. FEMS Microbiol. Lett. 42:23-25.
2. Arakere, G., and C. E. Frasch. 1991. Specificity of antibodies to O-acetylpositive and O-acetyl-negative group C meningococcal polysaccharides in sera from vaccinees and carriers. Infect. Immun. 59:4349-4356.
3. Azmi, F. H., A. H. Lucas, H. L. Spiegelberg, and D. M. Granoff. 1995. Human immunoglobulin M paraproteins cross-reactive with Neisseria meningitidis group B polysaccharide and fetal brain. Infect. Immun. 63:1906-1913.
4. 197 via adipic acid dihydrazide. Vaccine 1:463-170.
5. Bortolussi, R., and P. Ferrieri. 1980. Protection against Escherichia coli K1 infection in newborn rats by antibody to K1 capsular polysaccharide antigen. Infect. Immun. 28:111-117.
6. Bulkow, L. R., R. B. Wainwright, G. W. Letson, S. J. Chang, and J. I. Ward. 1993. Comparative immunogenicity of four Haemophilus influenzae type b conjugate vaccines in Alaskan native infants. Pediatr. Infect. Dis. J. 12:484-492.
7. Cadoz, M., J. Armand, F. Arminjon, R. Gire, and C. Lafaiz. 1985. Tetravalent (A,C.Y,W135) meningococcal vaccine in children: immunogenicity and safety. Vaccine 3:340-342.
8. Campbell, H., P. Byass, V. I. Ahonkhai, P. P. Vella, and B. M. Greenwood. 1990. Serologic responses to an Haemophilus influenzae type b polysaccha- ride-Neisseria meningitidis outer membrane protein conjugate vaccine in very young Gambian infants. Pediatrics 86:102-107.
9. Devi, S. J. N., R. Schneerson, W. Egan, W. F. Vann, J. B. Robbins, and J. Shiloach. 1991. Identity between polysaccharide antigens of Moraxella nonliquefaciens, group B Neisseria meningitidis, and Escherichia coli K1 (non-O acetylated). Infect. Immun. 59:732-736.
10. Devi, S. J. N., J. B. Robbins, and R. Schneerson. 1991. Antibodies to poly [(2→8)-α-N-acetyIneuraminic acid] and poly[(2→9)-α-N-acetylneuraminic acid] are elicited by immunization of mice with Escherichia coli K92 conjugates: potential vaccines for groups B and C meningococci and E. coli K1. Proc. Natl. Acad. Sci. USA 88:7175-7179.
11. Devi, S. J. N., C. E. Frasch, W. Zollinger, and P. J. Snoy. 1994. Immunization of juvenile rhesus monkeys with group B Neisseria meningitidis capsular polysaccharide-protéin conjugate vaccines, p. 427-429. In J. S. Evans, S. E. Yost, M. C. J. Maiden, and I. M. Feavers (ed.). Proceedings of the Ninth International Pathogenic Neisseria Conference. SCC, Reading, England.
12. Devi, S. J. N., A. Karpas, and C. E. Frasch. 1996. Binding diversity of monoclonal antibodies to a(2→8) polysialic acid conjugated to outer membrane vesicle via adipic acid dihydrazide. FEMS Immunol. Med. Microbiol. 14:211-220.
13. Finne, J. 1982. Occurrence of unique polysialosyl carbohydrate units in glycoproteins of developing brain. J. Biol. Chem. 257:11966-11970.
14. Finne, J., M. Leinonen, and P. H. Makela. 1983. Antigenic similarities between brain component and bacteria causing meningitis. Implications for vaccine development and pathogenesis. Lancet ii:355-357.
15. Frasch, C. E. 1995. Vaccines: past, present and future prospects, p. 245-283. In K. A. V. Cartwright (ed.), Meningococcal disease. Wiley & Sons, New York, N.Y.
16. Frasch, C. E., J. M. Zahradnik, L. Y. Wang, L. F. Mocca, and C. M. Tsai. 1988. Antibody response of adults to an aluminum hydroxide-adsorbed Neisseria meningitidis serotype 2b protein-group B polysaccharide vaccine. J. Infect. Dis. 158:710-718.
17. Goldschneider, I., E.G. Gotschlich, and M. S. Artenstein. 1969. Human immunity to the meningococcus. I. The role of humoral antibodies. J. Exp. Med. 129:1307-1326.
18. Granoff, D. M., and S. J. Holmes. 1991. Comparative immunogcnicity of Haemophilus influenzae type b polysaccharide-protein conjugate vaccines. Vaccine 9:530-534.
19. Gregson, N. A., C. Moreno, and M. R. Lifely. 1985. Monoclonal antibodies against meningococcal polysaccharide with cross-reactivity against brain antigens. Biochem. Soc. Trans. 13:462.
20. Griffis, J. M., B. L. Brandt, P. L. Altieri, G. B. Pier, and S. L. Berman. 1981. Safety and immunogenicity of group Y and group W135 meningococcal capsular polysaccharide vaccines in adults. Infect. Immun. 34:725-732.
21. Hayrinen, J., D. Bitter-Suermann, and J. Finne. 1989. Interaction of meningococcal group-B monoclonal antibody and its Fab fragment with α-2-8-linked sialic acid polymers-requirement of a long oligosaccharide segment for binding. Mol. Immunol. 26:523-529.
22. Hayrinen, J., H. Jennings, H. V. Raff, G. Rougon, N. Hanai, R. Gerardy-Schahn, and J. Finne. 1995. Antibodies to polysialic acid and its N-propyl derivative: binding properties and interaction with human embryonal brain glycopeptides. J. Infect. Dis. 171:1481-1490.
23. Husman, M., J. Roth, E. A. Kabat, C. Weisgerber, M. Frosch, and D. Bitter-Suermann. 1990. Immunohistochemical localization of polysialic acid in tissue sections: differential binding to polynucleotides and DNA of a murine IgG and a human IgM monoclonal antibody. J. Histochem. Cytochem. 38:209-215.
24. Jennings, H. J., R. Roy, and A. Gamian. 1986. Induction of meningococcal group B polysaccharide-specific IgG antibodies in mice using an N-propionylated B polysaccharide-tetanus toxoid conjugate vaccine. J. Immunol. 137: 1708-1713.
25. Jennings, H. J., R. Roy, and F. Michon. 1985. Determinant specificities of the groups B and C polysaccharides of Neisseria meningitidis. J. Immunol. 134: 2651-2657.
26. Johnson, J. R. 1991. Virulence factors in Escherichia coli urinary tract infection. Clin. Microbiol. Rev. 4:80-128.
27. Nov. J. Exp. Med. 168:699-711.
28. Kaijser, B. 1973. Immunology of Escherichia coli K antigen and its relation to urinary tract infection. J. Infect. Dis. 127:670-677.
29. Kasper, D. L., J. L. Winkelhake, W. D. Zollinger, B. L. Brandt, and M. S. Artenstein. 1973. Immunochcmical similarity between polysaccharide antigens of Escherichia coli O7:K1(L):NM and group B Neisseria meningitidis. J. Immunol. 110:262-268.
30. Lifely, M. R., C. Moreno, and J. C. Lindon. 1987. An integrated molecular and immunological approach towards a meningococcal group B vaccine. Vaccine 5:1126-1141.
31. Lifely, M. R., S. C. Roberts, W. M. Shephard, J. Esdaile, Z. Wang, A. Cleverly, A. A. Aulaqi, and C. Moreno. 1991. Immunogenicity in adult males of a Neisseria meningtidis group B vaccine composed of polysaccharide complexed with outer membrane proteins. Vaccine 9:60-66.
32. Mandrell, R. E., and W. D. Zollinger. 1982. Measurement of antibodies to meningococcal group B polysaccharide: low avidity binding and equilibrium binding constants. J. Immunol. 129:2172-2178.
33. Mandrell, R. E., F. H. Azmi, and D. M. Granoff. 1995. Complement-mediated bactericidal activity of human antibodies to poly α2→8 N-acetylneuraminic acid, the capsular polysaccharide of Neisseria meningitidis serogroup B. J. Infect. Dis. 172:1279-1289.
34. Moreno, C., M. R. Lifely, and J. Esdaile. 1985. Effect of aluminum ions on the chemical and immunochemical properties of meningococcal group B polysaccharide. Infect. Immun. 49:587-592.
35. Perera, A. D., C. F. Lagenaur, and T. M. Plant. 1993. Postnatal expression of polysialic acid-neural cell adhesion molecule in the hypothalamus of the male rhesus monkey (Macaco mulatto). Endocrinology 133:2729-2735.
36. Raff, H. V., D. Devereux, W. Shuford, D. Abbott-Brown, and G. Maloney. 1988. Human monoclonal antibody with protective activity for Escherichia coli K1 and Neisseria meningitidis group B infections. J. Infect. Dis. 157:118-126.
37. Roth, J., D. J. Taatjes, D. Bitter-Suermann, and J. Finne. 1987. Polysialic acid units are spatially and temporally expressed in developing postnatal rat kidney. Proc. Natl. Acad. Sci. USA 84:1969-1973.
38. Saukkonen, K., M. Haltia, M. Frosch, D. Bitter-Suerman, and M. Leinonen. 1986. Antibodies to the capsular polysaccharide of Neisseria meningitidis group B or E. coli K1 bind to the brains of infant rats in vitro but not in vivo. Microb. Pathog. 1:101-105.
39. Schneerson, R., J. B. Robbing, C. Chu, A. Sutton, W. Vann, J. C. Vickers, W. T. London, B. Curfman, M. C. Hardegree, J. Shiloach, and S. C. Rastogi. 1984. Serum antibody responses of juvenile and infant rhesus monkeys injected with Haemophilus type b and pneumococcus type 6A capsular poly- saccharide-protein conjugates. Infect. Immun. 45:582-591.
40. Tai, J. Y., F. Michon, and P. C. Fusco. 1995. Antibody-dependent, complement-mediated bactericidal activity elicited by group B meningococcal conjugate vaccines in mice and nonhuman primates, abstr. G3, p. 159. In Abstracts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
41. Weinberg, G. A., M. S. Einhorn, A. A. Lenoir, P. D. Granoff, and D. M. Granoff. 1987. Immunologic priming to capsular polysaccharide in infants immunized with Haernophilus influenzae type b polysaccharide-Neisseria meningitidis outer membrane protein conjugate vaccine. J. Pediatr. 111:22-27.
42. Wyle, F. A., M. S. Artenstein, B. L. Brandt, E. C. Traumont, D. L. Kasper, P. L. Alten, S. L. Herman, and J. P. Lowenthal. 1972. Immunologic response of man to group B meningococcal polysaccharide vaccine. J. Infect. Dis. 126:514-522.
43. Zollinger, W. D., R. E. Mandrell, J. M. Griffis, P. Altieri, and S. Berman. 1979. Complex of meningococcal group B polysaccharide and type 2 outer membrane protein immunogenic in man. J. Clin. Invest. 63:836-848.
44. Zollinger, W. D., J. E. Boslego, C. E. Frasch, and L. O. Froholm. 1984. Safety of vaccines containing meningococcal group B polysaccharide. Lancet ii:166.
45. Zollinger, W. D., C. E. Frasch, S. J. N. Devi, E. E. Moran, and P. J. Snoy. 1994. Bactericidal antibody responses of juvenile rhesus monkeys to conjugate B polysaccharide vaccines, p. 441-442. In J. S. Evans, S. E. Yost, M. C. J. Maiden, and I. M. Feavers (ed.), Proceedings of the Ninth International Pathogenic Neisseria Conference. SCC, Reading, England.
46. Zollinger, W. D., E. E. Moran, S. J. N. Devi, and C. E. Frasch. 1997. Bactericidal antibody responses of juvenile rhesus monkeys immunized with group B Neisseria meningitidis capsular polysaccharide-protein conjugate vaccines. Infect. Immun. 65:1053-1060.