Radiation-Induced Astrogliosis and Blood-Brain Barrier Damage Can Be Abrogated Using Anti-TNF Treatment

International Journal of Radiation Oncology Biology Physics

Volumn 74, Issue 3, 2009, Pages 934-941

  Wilson, Christy M ^a   Gaber, M Waleed ^a   Sabek, Omaima M ^b   Zawaski, Janice A ^a   Merchant, Thomas E ^a,c  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Astrogliosis; Blood brain barrier; Radiation toxicity; Tumor necrosis factor; Vascular response

Indexed keywords

ASTROGLIOSIS; BLOOD-BRAIN BARRIER; RADIATION TOXICITY; TUMOR NECROSIS FACTOR; VASCULAR RESPONSE;

ANIMALS; BLOOD; CAPILLARITY; FLUORESCENCE; GLUCOSE; GLYCOPROTEINS; MACROPHAGES; TOXICITY; TUMORS;

ADHESION;

FLUORESCEIN ISOTHIOCYANATE DEXTRAN; INTERCELLULAR ADHESION MOLECULE 1; MONOCLONAL ANTIBODY MP6 XT3; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; RHODAMINE 6G; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTERIOLE; ARTICLE; ASTROCYTE; ASTROCYTOSIS; BLOOD BRAIN BARRIER DAMAGE; BLOOD VESSEL DIAMETER; BRAIN CORTEX; BRAIN DAMAGE; BRAIN RADIATION; BRAIN TISSUE; CANCER RADIOTHERAPY; CELL ACTIVATION; CENTRAL NERVOUS SYSTEM TUMOR; CONTROLLED STUDY; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; LEUKOCYTE ADHERENCE; MALE; MICROSCOPY; MOUSE; NONHUMAN; PIA ARTERY; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; RADIATION DOSE; VENULE;

ANIMALS; ANTIBODY SPECIFICITY; ARTERIOLES; ASTROCYTES; BLOOD-BRAIN BARRIER; BRAIN; CELL ADHESION; CENTRAL NERVOUS SYSTEM NEOPLASMS; CRANIAL IRRADIATION; DEXTRANS; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT ANTIBODY TECHNIQUE; INTERCELLULAR ADHESION MOLECULE-1; LEUKOCYTE COUNT; LEUKOCYTES; MALE; MICE; MICE, INBRED C57BL; PERMEABILITY; RADIATION DOSAGE; RECOMBINANT PROTEINS; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA; VENULES;

EID: 67049096054     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.02.035     Document Type: Article

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