The role of adenosine in hypercarbic hyperemia: In vivo and in vitro studies in adenosine 2A receptor knockout and wild-type mice. Laboratory investigation

Journal of Neurosurgery

Volumn 110, Issue 5, 2009, Pages 981-988

  Miekisiak, Grzegorz ^a   Yoo, Kristen ^a   Sandler, Adam L ^a   Kulik, Tobias B ^a   Chen, Jiang Fan ^b   Winn, H Richard ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Brain adenosine; Cerebral blood flow; Hypercarbia; Knockout mouse

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 4 [2 [7 AMINO 2 (2 FURYL) 1,2,4 TRIAZOLO[2,3 A][1,3,5]TRIAZIN 5 YLAMINO]ETHYL]PHENOL; ADENOSINE; ADENOSINE A2 RECEPTOR; AMINOPHYLLINE; ADENOSINE A2A RECEPTOR; CARBON DIOXIDE; DRUG DERIVATIVE; PHENETHYLAMINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTICLE; BRAIN BLOOD FLOW; CARBON DIOXIDE TENSION; CARDIOVASCULAR RESPONSE; COMPARATIVE STUDY; CONTROLLED STUDY; HYPERCAPNIA; HYPEREMIA; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; LASER DOPPLER FLOWMETRY; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN FUNCTION; SIMULATION; VASODILATATION; WILD TYPE; ANIMAL; BLOOD; BRAIN CIRCULATION; C57BL MOUSE; DRUG ANTAGONISM; MOUSE MUTANT; PATHOPHYSIOLOGY; PHYSIOLOGY; PRESSURE;

ADENOSINE; ANIMALS; CARBON DIOXIDE; CEREBROVASCULAR CIRCULATION; HYPEREMIA; LASER-DOPPLER FLOWMETRY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PARTIAL PRESSURE; PHENETHYLAMINES; RECEPTOR, ADENOSINE A2A;

EID: 66849122079     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2008.8.JNS08460     Document Type: Article

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