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Volumn 20, Issue 8, 2009, Pages 780-790

Non-invasive markers of airway inflammation and remodeling in childhood asthma

Author keywords

Childhood asthma; Exacerbations; Inflammation; Sputum

Indexed keywords

FLUTICASONE PROPIONATE; GELATINASE B; INTERLEUKIN 8; NITRIC OXIDE; SALMETEROL; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSCRIPTION FACTOR RELA;

EID: 66749178948     PISSN: 09056157     EISSN: 13993038     Source Type: Journal    
DOI: 10.1111/j.1399-3038.2009.00945.x     Document Type: Article
Times cited : (40)

References (48)
  • 2
    • 0032938331 scopus 로고    scopus 로고
    • Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment. the AMPUL Study Group
    • Sont JK, Willems LN, Bel EH, van Krieken JH, Vandenbroucke JP, Sterk PJ. Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment. The AMPUL Study Group. Am J Respir Crit Care Med 1999 159 (4 Pt 1 1043 1051.
    • (1999) Am J Respir Crit Care Med , vol.159 , Issue.PART 1 , pp. 1043-1051
    • Sont, J.K.1    Willems, L.N.2    Bel, E.H.3    Van Krieken, J.H.4    Vandenbroucke, J.P.5    Sterk, P.J.6
  • 4
    • 14644412828 scopus 로고    scopus 로고
    • Markers of eosinophilic inflammation and tissue re-modelling in children before clinically diagnosed bronchial asthma
    • Pohunek P, Warner JO, Turzikova J, Kudrmann J, Roche WR. Markers of eosinophilic inflammation and tissue re-modelling in children before clinically diagnosed bronchial asthma. Pediatr Allergy Immunol 2005 : 16 : 43 51.
    • (2005) Pediatr Allergy Immunol , vol.16 , pp. 43-51
    • Pohunek, P.1    Warner, J.O.2    Turzikova, J.3    Kudrmann, J.4    Roche, W.R.5
  • 5
    • 0035117229 scopus 로고    scopus 로고
    • Eosinophil cationic protein and interleukin-8 levels in bronchial lavage fluid from children with asthma and infantile wheeze
    • Marguet C, Dean TP, Basuyau JP, Warner JO. Eosinophil cationic protein and interleukin-8 levels in bronchial lavage fluid from children with asthma and infantile wheeze. Pediatr Allergy Immunol 2001 : 12 : 27 33.
    • (2001) Pediatr Allergy Immunol , vol.12 , pp. 27-33
    • Marguet, C.1    Dean, T.P.2    Basuyau, J.P.3    Warner, J.O.4
  • 6
    • 0037794412 scopus 로고    scopus 로고
    • Clinical and biological heterogeneity in children with moderate asthma
    • La Grutta S, Gagliardo R, Mirabella F, et al. Clinical and biological heterogeneity in children with moderate asthma. Am J Respir Crit Care Med 2003 : 167 : 1490 1495.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 1490-1495
    • La Grutta, S.1    Gagliardo, R.2    Mirabella, F.3
  • 7
    • 18644373492 scopus 로고    scopus 로고
    • Clinical use of noninvasive measurements of airway inflammation in steroid reduction in children
    • Zacharasiewicz A, Wilson N, Lex C, et al. Clinical use of noninvasive measurements of airway inflammation in steroid reduction in children. Am J Respir Crit Care Med 2005 : 171 : 1077 1082.
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 1077-1082
    • Zacharasiewicz, A.1    Wilson, N.2    Lex, C.3
  • 9
    • 0034931525 scopus 로고    scopus 로고
    • Asthma severity and inflammation markers in children
    • Wilson NM, James A, Uasuf C, et al. Asthma severity and inflammation markers in children. Pediatr Allergy Immunol 2001 : 12 : 125 132.
    • (2001) Pediatr Allergy Immunol , vol.12 , pp. 125-132
    • Wilson, N.M.1    James, A.2    Uasuf, C.3
  • 11
    • 0037202790 scopus 로고    scopus 로고
    • Asthma exacerbations and sputum eosinophil counts: A randomised controlled trial
    • Green RH, Brightling CE, McKenna S, et al. Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet 2002 : 360 : 1715 1721.
    • (2002) Lancet , vol.360 , pp. 1715-1721
    • Green, R.H.1    Brightling, C.E.2    McKenna, S.3
  • 12
    • 24644519265 scopus 로고    scopus 로고
    • Titrating steroids on exhaled nitric oxide in children with asthma: A randomized controlled trial
    • Pijnenburg MW, Bakker EM, Hop WC, De Jongste JC. Titrating steroids on exhaled nitric oxide in children with asthma: a randomized controlled trial. Am J Respir Crit Care Med 2005 : 172 : 831 836.
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 831-836
    • Pijnenburg, M.W.1    Bakker, E.M.2    Hop, W.C.3    De Jongste, J.C.4
  • 13
    • 14344264164 scopus 로고    scopus 로고
    • Biochemical interaction between effects of beclomethasone dipropionate and salbutamol or formoterol in sputum cells from mild to moderate asthmatics
    • Profita M, Gagliardo R, Di Giorgi R, et al. Biochemical interaction between effects of beclomethasone dipropionate and salbutamol or formoterol in sputum cells from mild to moderate asthmatics. Allergy 2005 : 60 : 323 329.
    • (2005) Allergy , vol.60 , pp. 323-329
    • Profita, M.1    Gagliardo, R.2    Di Giorgi, R.3
  • 14
    • 0032417102 scopus 로고    scopus 로고
    • Sputum metalloproteinase-9/tissue inhibitor of metalloproteinase-1 ratio correlates with airflow obstruction in asthma and chronic bronchitis
    • Vignola AM, Riccobono L, Mirabella A, et al. Sputum metalloproteinase-9/ tissue inhibitor of metalloproteinase-1 ratio correlates with airflow obstruction in asthma and chronic bronchitis. Am J Respir Crit Care Med 1998 : 158 : 1945 1950.
    • (1998) Am J Respir Crit Care Med , vol.158 , pp. 1945-1950
    • Vignola, A.M.1    Riccobono, L.2    Mirabella, A.3
  • 15
    • 39449123817 scopus 로고    scopus 로고
    • Differences in airway cytokine profile in severe asthma compared to moderate asthma
    • Shannon J, Ernst P, Yamauchi Y, et al. Differences in airway cytokine profile in severe asthma compared to moderate asthma. Chest 2008 : 133 : 420 426.
    • (2008) Chest , vol.133 , pp. 420-426
    • Shannon, J.1    Ernst, P.2    Yamauchi, Y.3
  • 16
    • 0033930349 scopus 로고    scopus 로고
    • Glucocorticoid receptor alpha and beta in glucocorticoid dependent asthma
    • Gagliardo R, Chanez P, Vignola AM, et al. Glucocorticoid receptor alpha and beta in glucocorticoid dependent asthma. Am J Respir Crit Care Med 2000 : 162 : 7 13.
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 7-13
    • Gagliardo, R.1    Chanez, P.2    Vignola, A.M.3
  • 17
    • 0027181170 scopus 로고
    • The lack of distensibility of asthmatic airways
    • Wilson JW, Li X, Pain MC. The lack of distensibility of asthmatic airways. Am Rev Respir Dis. 1993 : 148 : 806 809.
    • (1993) Am Rev Respir Dis. , vol.148 , pp. 806-809
    • Wilson, J.W.1    Li, X.2    Pain, M.C.3
  • 18
    • 0031092090 scopus 로고    scopus 로고
    • Eosinophils as a source of matrix metalloproteinase-9 in asthmatic airway inflammation
    • Ohno I, Ohtani H, Nitta Y, et al. Eosinophils as a source of matrix metalloproteinase-9 in asthmatic airway inflammation. Am J Respir Cell Mol Biol 1997 : 16 : 212 219.
    • (1997) Am J Respir Cell Mol Biol , vol.16 , pp. 212-219
    • Ohno, I.1    Ohtani, H.2    Nitta, Y.3
  • 19
    • 24144482766 scopus 로고    scopus 로고
    • Differential proteolytic enzyme activity in eosinophilic and neutrophilic asthma
    • Simpson JL, Scott RJ, Boyle MJ, Gibson PG. Differential proteolytic enzyme activity in eosinophilic and neutrophilic asthma. Am J Respir Crit Care Med 2005 : 172 : 559 565.
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 559-565
    • Simpson, J.L.1    Scott, R.J.2    Boyle, M.J.3    Gibson, P.G.4
  • 20
    • 0034667542 scopus 로고    scopus 로고
    • Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-alpha and leaves RANTES and MCP-2 intact
    • Van den Steen PE, Proost P, Wuyts A, Van Damme J, Opdenakker G. Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-alpha and leaves RANTES and MCP-2 intact. Blood 2000 : 96 : 2673 2681.
    • (2000) Blood , vol.96 , pp. 2673-2681
    • Van Den Steen, P.E.1    Proost, P.2    Wuyts, A.3    Van Damme, J.4    Opdenakker, G.5
  • 21
    • 0242459769 scopus 로고    scopus 로고
    • Persistent activation of nuclear factor-kappaB signaling pathway in severe uncontrolled asthma
    • Gagliardo R, Chanez P, Mathieu M, et al. Persistent activation of nuclear factor-kappaB signaling pathway in severe uncontrolled asthma. Am J Respir Crit Care Med 2003 : 168 : 1190 1198.
    • (2003) Am J Respir Crit Care Med , vol.168 , pp. 1190-1198
    • Gagliardo, R.1    Chanez, P.2    Mathieu, M.3
  • 22
    • 0033607313 scopus 로고    scopus 로고
    • The NF-kappa B activation pathway: A paradigm in information transfer from membrane to nucleus
    • Rothwarf DM, Karin M. The NF-kappa B activation pathway: a paradigm in information transfer from membrane to nucleus. Sci STKE 1999 : 1999 : RE1.
    • (1999) Sci STKE , vol.1999
    • Rothwarf, D.M.1    Karin, M.2
  • 23
    • 0029926229 scopus 로고    scopus 로고
    • Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-activated protein kinase kinase 1-independent and requires multiple transcription factor binding sites including closely spaced PEA3/ets and AP-1 sequences
    • Gum R, Lengyel E, Juarez J, et al. Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-activated protein kinase kinase 1-independent and requires multiple transcription factor binding sites including closely spaced PEA3/ets and AP-1 sequences. J Biol Chem 1996 : 271 : 10672 10680.
    • (1996) J Biol Chem , vol.271 , pp. 10672-10680
    • Gum, R.1    Lengyel, E.2    Juarez, J.3
  • 24
    • 33845955238 scopus 로고    scopus 로고
    • A novel mechanism of tissue inhibitor of metalloproteinases-1 activation by interleukin-1 in primary human astrocytes
    • Wilczynska KM, Gopalan SM, Bugno M, et al. A novel mechanism of tissue inhibitor of metalloproteinases-1 activation by interleukin-1 in primary human astrocytes. J Biol Chem 2006 : 281 : 34955 34964.
    • (2006) J Biol Chem , vol.281 , pp. 34955-34964
    • Wilczynska, K.M.1    Gopalan, S.M.2    Bugno, M.3
  • 25
    • 71449099216 scopus 로고    scopus 로고
    • Global Initiative for Asthma (GINA). National Institutes of Health, National Heart, Lung and Blood Institute. NHI Publication N. 02-3659.
    • Global Initiative for Asthma (GINA). Workshop report, Global Strategy for Asthma Management and Prevention, 2005 : National Institutes of Health, National Heart, Lung and Blood Institute. NHI Publication N. 02-3659.
    • (2005) Workshop Report, Global Strategy for Asthma Management and Prevention
  • 27
    • 0027436007 scopus 로고
    • Skin testing. the safety of skin tests and the information obtained from using different methods and concentrations of allergen.
    • Dreborg S. Skin testing. The safety of skin tests and the information obtained from using different methods and concentrations of allergen. Allergy 1993 : 48 : 473 475.
    • (1993) Allergy , vol.48 , pp. 473-475
    • Dreborg, S.1
  • 28
    • 0036161879 scopus 로고    scopus 로고
    • Decreased morning serum cortisol levels in ticasone propionate
    • Eid N, Morton R, Olds B, Clark P, Sheikh S, Looney S. Decreased morning serum cortisol levels in ticasone propionate. Pediatrics 2002 : 109 : 217 221.
    • (2002) Pediatrics , vol.109 , pp. 217-221
    • Eid, N.1    Morton, R.2    Olds, B.3    Clark, P.4    Sheikh, S.5    Looney, S.6
  • 29
    • 0023145035 scopus 로고
    • Value of basal plasma cortisol assays in the assessment of pituitary-adrenal insufficiency
    • Hagg E, Asplund K, Lithner F. Value of basal plasma cortisol assays in the assessment of pituitary-adrenal insufficiency. Clin Endocrinol 1987 : 26 : 221 226.
    • (1987) Clin Endocrinol , vol.26 , pp. 221-226
    • Hagg, E.1    Asplund, K.2    Lithner, F.3
  • 30
    • 1842370350 scopus 로고    scopus 로고
    • Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group
    • Pauwels RA, Lofdahl CG, Postma DS, et al. Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group. N Engl J Med 1997 : 337 : 1405 1411.
    • (1997) N Engl J Med , vol.337 , pp. 1405-1411
    • Pauwels, R.A.1    Lofdahl, C.G.2    Postma, D.S.3
  • 31
    • 0032787222 scopus 로고    scopus 로고
    • Lung function and sputum characteristics of patients with severe asthma during an induced exacerbation by double-blind steroid withdrawal
    • in't Veen JC, Smits HH, Hiemstra PS, Zwinderman AE, Sterk PJ, Bel EH. Lung function and sputum characteristics of patients with severe asthma during an induced exacerbation by double-blind steroid withdrawal. Am J Respir Crit Care Med 1999 : 160 : 93 9.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 93-9
    • In'T Veen, J.C.1    Smits, H.H.2    Hiemstra, P.S.3    Zwinderman, A.E.4    Sterk, P.J.5    Bel, E.H.6
  • 33
    • 0035482240 scopus 로고    scopus 로고
    • The tolerability, safety, and success of sputum induction and combined hypertonic saline challenge in children
    • Jones PD, Hankin R, Simpson J, Gibson PG, Henry RL. The tolerability, safety, and success of sputum induction and combined hypertonic saline challenge in children. Am J Respir Crit Care Med 2001 : 164 : 1146 1149.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 1146-1149
    • Jones, P.D.1    Hankin, R.2    Simpson, J.3    Gibson, P.G.4    Henry, R.L.5
  • 34
    • 0027752988 scopus 로고
    • Sputum measurements to assess airway inflammation in asthma
    • Hargreave FE, Popov T, Kidney J, Dolovich J. Sputum measurements to assess airway inflammation in asthma. Allergy. 1993 : 48 : 81 3.
    • (1993) Allergy. , vol.48 , pp. 81-3
    • Hargreave, F.E.1    Popov, T.2    Kidney, J.3    Dolovich, J.4
  • 35
    • 0030711063 scopus 로고    scopus 로고
    • Corticosteroids decrease exhaled nitric oxide in children with acute asthma
    • Baraldi E, Azzolin NM, Zanconato S, Dario C, Zacchello F. Corticosteroids decrease exhaled nitric oxide in children with acute asthma. J Pediatr 1997 : 131 : 381 385.
    • (1997) J Pediatr , vol.131 , pp. 381-385
    • Baraldi, E.1    Azzolin, N.M.2    Zanconato, S.3    Dario, C.4    Zacchello, F.5
  • 36
    • 0027379178 scopus 로고
    • Induction of nitric oxide synthase in asthma
    • Hamid Q, Springall DR, Riveros-Moreno V, et al. Induction of nitric oxide synthase in asthma. Lancet 1993 : 342 : 1510 1513.
    • (1993) Lancet , vol.342 , pp. 1510-1513
    • Hamid, Q.1    Springall, D.R.2    Riveros-Moreno, V.3
  • 37
    • 0037339282 scopus 로고    scopus 로고
    • Reproducibility of exhaled nitric oxide measurements in healthy and asthmatic adults and children
    • Kharitonov SA, Gonio F, Kelly C, Meah S, Barnes PJ. Reproducibility of exhaled nitric oxide measurements in healthy and asthmatic adults and children. Eur Respir J 2003 : 3 : 433 438.
    • (2003) Eur Respir J , vol.3 , pp. 433-438
    • Kharitonov, S.A.1    Gonio, F.2    Kelly, C.3    Meah, S.4    Barnes, P.J.5
  • 38
    • 33748089974 scopus 로고    scopus 로고
    • Exhaled nitric oxide in the management of childhood asthma: A prospective 6-months study
    • Fritsch M, Uxa S, Horak F Jr., et al. Exhaled nitric oxide in the management of childhood asthma: a prospective 6-months study. Pediatr Pulmonol 2006 : 41 : 855 862.
    • (2006) Pediatr Pulmonol , vol.41 , pp. 855-862
    • Fritsch, M.1    Uxa, S.2    Horak Jr., F.3
  • 39
    • 0347477331 scopus 로고    scopus 로고
    • Heterogeneity of FeNO response to inhaled steroid in asthmatic children
    • Buchvald F, Eiberg H, Bisgaard H. Heterogeneity of FeNO response to inhaled steroid in asthmatic children. Clin Exp Allergy 2003 : 33 : 1735 1740.
    • (2003) Clin Exp Allergy , vol.33 , pp. 1735-1740
    • Buchvald, F.1    Eiberg, H.2    Bisgaard, H.3
  • 40
    • 34548514252 scopus 로고    scopus 로고
    • Exhaled nitric oxide and biomarkers in exhaled breath condensate indicate the presence, severity and control of childhood asthma
    • Robroeks CM, van de Kant KD, Jöbsis Q, et al. Exhaled nitric oxide and biomarkers in exhaled breath condensate indicate the presence, severity and control of childhood asthma. Clin Exp Allergy 2007 : 37 : 1303 1311.
    • (2007) Clin Exp Allergy , vol.37 , pp. 1303-1311
    • Robroeks, C.M.1    Van De Kant, K.D.2    Jöbsis, Q.3
  • 41
    • 13444267772 scopus 로고    scopus 로고
    • Oral corticosteroids decrease eosinophil and CC chemokine expression but increase neutrophil, IL-8, and IFN-gamma-inducible protein 10 expression in asthmatic airway mucosa
    • Fukakusa M, Bergeron C, Tulic MK, et al. Oral corticosteroids decrease eosinophil and CC chemokine expression but increase neutrophil, IL-8, and IFN-gamma-inducible protein 10 expression in asthmatic airway mucosa. J Allergy Clin Immunol 2005 : 115 : 280 286.
    • (2005) J Allergy Clin Immunol , vol.115 , pp. 280-286
    • Fukakusa, M.1    Bergeron, C.2    Tulic, M.K.3
  • 42
    • 0034063744 scopus 로고    scopus 로고
    • Interleukin-8 secretion and neutrophil recruitment accompanies induced sputum eosinophil activation in children with acute asthma
    • Norzila MZ, Fakes K, Henry RL, Simpson J, Gibson PG. Interleukin-8 secretion and neutrophil recruitment accompanies induced sputum eosinophil activation in children with acute asthma. Am J Respir Crit Care Med 2000 : 161 : 769 774.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 769-774
    • Norzila, M.Z.1    Fakes, K.2    Henry, R.L.3    Simpson, J.4    Gibson, P.G.5
  • 43
    • 84941944723 scopus 로고    scopus 로고
    • Ultrastructural examination of bronchial biopsy specimens from children with moderate asthma
    • Cokùraş H, Akçakaya N, Seçkin S, Camciòlu Y, Sarimurat N, Aksoy F. Ultrastructural examination of bronchial biopsy specimens from children with moderate asthma. Thorax 2001 : 56 : 25 9.
    • (2001) Thorax , vol.56 , pp. 25-9
    • Cokùraş, H.1    Akçakaya, N.2    Seçkin, S.3    Camciòlu, Y.4    Sarimurat, N.5    Aksoy, F.6
  • 44
    • 52649121376 scopus 로고    scopus 로고
    • Bronchoalveolar Lavage MMP-9 and TIMP-1 in Preschool Wheezers and Their Relationship to Persistent Wheeze
    • Erlewyn-Lajeunesse MD, Hunt LP, Pohunek P, et al. Bronchoalveolar Lavage MMP-9 and TIMP-1 in Preschool Wheezers and Their Relationship to Persistent Wheeze. Pediatr Res 2008 : 64 : 194 199.
    • (2008) Pediatr Res , vol.64 , pp. 194-199
    • Erlewyn-Lajeunesse, M.D.1    Hunt, L.P.2    Pohunek, P.3
  • 45
    • 3442896883 scopus 로고    scopus 로고
    • Cytokine-regulated accumulation of eosinophils in inflammatory disease
    • Lampinen M, Carlson M, Håkansson LD, Venge P. Cytokine-regulated accumulation of eosinophils in inflammatory disease. Allergy 2004 : 59 : 793 805.
    • (2004) Allergy , vol.59 , pp. 793-805
    • Lampinen, M.1    Carlson, M.2    Håkansson, L.D.3    Venge, P.4
  • 46
    • 14944353086 scopus 로고    scopus 로고
    • Exhaled nitric oxide predicts asthma relapse in children with clinical asthma remission
    • Pijnenburg MW, Hofhuis W, Hop WC, De Jongste JC. Exhaled nitric oxide predicts asthma relapse in children with clinical asthma remission. Thorax 2005 : 60 : 215 218.
    • (2005) Thorax , vol.60 , pp. 215-218
    • Pijnenburg, M.W.1    Hofhuis, W.2    Hop, W.C.3    De Jongste, J.C.4
  • 47
    • 0032875377 scopus 로고    scopus 로고
    • Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics
    • Wenzel SE, Schwartz LB, Langmack EL, et al. Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics. Am J Respir Crit Care Med 1999 : 160 : 1001 1008.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1001-1008
    • Wenzel, S.E.1    Schwartz, L.B.2    Langmack, E.L.3


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