Levels of vascular endothelial growth factor and pigment epithelium-derived factor in eyes before and after intravitreal injection of bevacizumab

Japanese Journal of Ophthalmology

Volumn 53, Issue 3, 2009, Pages 243-248

  Matsuyama, Kayako ^a   Ogata, Nahoko ^a   Jo, Nobuo ^a   Shima, Chieko ^a   Matsuoka, Masato ^a   Matsumura, Miyo ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

Bevacizumab (Avastin); Diabetic retinopathy; Neovascularization; Pigment epithelium derived factor (PEDF); Vascular endothelial growth factor (VEGF)

Indexed keywords

BEVACIZUMAB; PIGMENT EPITHELIUM DERIVED FACTOR; VASCULOTROPIN;

ADULT; AGED; AQUEOUS HUMOR; ARTICLE; BLEEDING; CLINICAL ARTICLE; DIABETIC RETINOPATHY; DISEASE SEVERITY; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MALE; NEOVASCULAR GLAUCOMA; OFF LABEL DRUG USE; PEROPERATIVE COMPLICATION; PRIORITY JOURNAL; SUBRETINAL NEOVASCULARIZATION; TREATMENT OUTCOME; VITRECTOMY;

ADULT; AGED; ANGIOGENESIS INHIBITORS; ANTIBODIES, MONOCLONAL; AQUEOUS HUMOR; DIABETES MELLITUS, TYPE 2; DIABETIC RETINOPATHY; ENZYME-LINKED IMMUNOSORBENT ASSAY; EYE PROTEINS; FEMALE; HUMANS; INJECTIONS; MALE; MIDDLE AGED; NERVE GROWTH FACTORS; RETINAL NEOVASCULARIZATION; SERPINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VITREOUS BODY;

EID: 66749167000     PISSN: 00215155     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10384-008-0645-4     Document Type: Article

References (32)

1. A.P. Adamis J.W. Miller M.T. Bernal 1994 Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy Am J Ophthalmol 118 445 450 (Pubitemid 24307211)
2. L.P. Aiello R.L. Avery P.G. Arrigg 1994 Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders N Engl J Med 331 1480 1487 (Pubitemid 24356306)
3. F. Malecaze S. Clamens V. Simorre-Pinatel 1994 Detection of vascular endothelial growth factor messenger RNA and vascular endothelial growth factor-like activity in proliferative diabetic retinopathy Arch Ophthalmol 112 1476 1482 (Pubitemid 24350514)
4. A.P. Adamis D.T. Shima M.J. Tolentino 1996 Inhibition of vascular endothelial growth factor prevents retinal ischemia associated iris neovascularization in a nonhuman primate Arch Ophthalmol 114 66 71 (Pubitemid 26026196)
5. L.P. Aiello E.A. Pierce E.D. Foley 1995 Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins Proc Natl Acad Sci U S A 92 10457 10461
6. P.J. Rosenfeld A.A. Moshfeghi C.A. Puliafito 2005 Optical coherence tomography findings after an intravitreal injection of bevacizumab (Avastin) for neovascular age-related macular degeneration Ophthalmic Surg Lasers Imaging 36 331 335 (Pubitemid 41073112)
7. R.L. Avery D.J. Pieramici M.D. Rabena A.A. Castellarin M.A. Nasir M.J. Giust 2006 Intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration Ophthalmology 113 363 372
8. P.J. Rosenfeld A.E. Fung C.A. Puliafito 2005 Optical coherence tomography findings after an intravitreal injection of bevacizumab (Avastin) for macular edema from central retinal vein occlusion Ophthalmic Surg Lasers Imaging 36 336 339 (Pubitemid 41073113)
9. R.L. Avery 2006 Regression of retinal and iris neovascularization after intravitreal bevacizumab (Avastin) Retina 26 352 354 (Pubitemid 44318195)
10. R. Jorge R.A. Costa D. Calucci L.P. Cintra I.U. Scott 2006 Intravitreal bevacizumab (Avastin) for persistent new vessels in diabetic retinopathy (IBEPE study) Retina 26 1006 1013 (Pubitemid 44973219)
11. R.L. Avery J. Pearlman D.J. Pieramici 2006 Intravitreal bevacizumab (Avastin) in the treatment of proliferative diabetic retinopathy Ophthalmology 113 1695 1705
12. C. Haritoglou D. Kook A. Neubauer 2006 Intravitreal bevacizumab (Avastin) therapy for persistent diffuse diabetic macular edema Retina 26 999 1005 (Pubitemid 44973218)
13. M.Y. Kahook J.S. Schuman R.J. Noecker 2006 Intravitreal bevacizumab in a patient with neovascular glaucoma Ophthalmic Surg Lasers Imaging 37 144 146
14. F.H. Davidorf J.G. Mouser R.J. Derick 2006 Rapid improvement of rubeosis iridis from a single bevacizumab (Avastin) injection Retina 26 354 356 (Pubitemid 44318196)
15. S. Yazdani K. Hendi M. Pakravan 2007 Intravitreal bevacizumab (Avastin) injection for neovascular glaucoma J Glaucoma 16 437 439 (Pubitemid 47263045)
16. J. Tombran-Tink L.V. Johnson 1989 Neuronal differentiation of retinoblastoma cells induced by medium conditioned by human RPE cells Invest Ophthalmol Vis Sci 30 1700 1707 (Pubitemid 19214990)
17. D.W. Dawson O.V. Volpert P. Gillis 1999 Pigment epithelium-derived factor: a potent inhibitor of angiogenesis Science 285 245 248 (Pubitemid 29329995)
18. V. Stellmach S.E. Crawford W. Zhou N. Bouck 2001 Prevention of ischemia-induced retinopathy by the natural ocular antiangiogenic agent pigment epithelium-derived factor Proc Nat Acad Soc U S A 98 2593 2597 (Pubitemid 32209527)
19. J. Spranger M. Osterhoff M. Reimann 2001 Loss of antiangiogenic pigment epithelium-derived factor in patients with angiogenic eye diseases Diabetes 50 2641 2645 (Pubitemid 33733112)
20. N. Ogata J. Tombran-Tink M. Nishikawa 2001 Pigment epithelium-derived factor in the vitreous is low in diabetic retinopathy and high in rhegmatogenous retinal detachment Am J Ophthalmol 132 378 382 (Pubitemid 32768607)
21. N. Ogata M. Nishikawa T. Nishimura Y. Mitsuma M. Matsumura 2002 Unbalanced vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor in diabetic retinopathy Am J Ophthalmol 134 348 353
22. K. Mori E. Duh P. Gehlbach 2001 Pigment epithelium-derived factor inhibits retinal and choroidal neovascularization J Cell Physiol 188 253 263 (Pubitemid 32622916)
23. H. Liu J.G. Ren W.L. Cooper C.E. Hawkins M.R. Cowan P.Y. Tonq 2004 Identification of the antivasopermeability effect of pigment epithelium-derived factor and its active site Proc Natl Acad Sci U S A 101 6605 6610 (Pubitemid 38586021)
24. K. Ohno-Matsui T. Yoshida T. Uetama M. Mochizuki I. Morita 2003 Vascular endothelial growth factor up-regulates pigment epithelium-derived factor expression via VEGFR-1 in human retinal pigment epithelial cells Biochem Biophys Res Commun 303 962 967 (Pubitemid 36384949)
25. J. Mordenti K. Thomsen V. Licko 1999 Intraocular pharmacokinetics and safety of a humanized monoclonal antibody in rabbits after intravitreal administration of a solution or a PLGA microsphere formulation Toxicol Sci 52 101 106
26. J. Shahar R.L. Avery G. Heilweil 2006 Electrophysiologic and retinal penetration studies following intravitreal injection of bevacizumab (Avastin) Retina 26 262 269 (Pubitemid 44318177)
27. P. Heiduschka H. Fietz S. Hofmeister 2007 Tubingen Bevacizumab Study Group. Penetration of bevacizumab through the retina after intravitreal injection in the monkey Invest Ophthalmol Vis Sci 48 2814 2823
28. S.J. Bakri M.R. Snyder J.M. Reid J.S. Pulido R.J. Singh 2007 Pharmacokinetics of intravitreal bevacizumab (Avastin) Ophthalmology 114 855 859 (Pubitemid 46635858)
29. O. Sawada H. Kawamura M. Kakinoki T. Sawada M. Ohji 2007 Vascular endothelial growth factor in aqueous humor before and after intravitreal injection of bevacizumab in eyes with diabetic retinopathy Arch Ophthalmol 125 1363 1366 (Pubitemid 47606601)
30. K. Miyamoto S. Khosrof S.E. Bursell 2000 Vascular endothelial growth factor (VEGF)-induced retinal vascular permeability is mediated by intercellular adhesion molecule-1 (ICAM-1) Am J Pathol 156 1733 1739 (Pubitemid 30646710)
31. M. Matsuoka N. Ogata K. Minamino M. Matsumura 2007 Leukostasis and pigment epithelium-derived factor in rat models of diabetic retinopathy Mol Vis 13 1058 1065 (Pubitemid 47034649)
32. S.X. Zhang J.J. Wang G. Gao K. Parke J.X. Ma 2006 Pigment epithelium-derived factor downregulates vascular endothelial growth factor (VEGF) expression and inhibits VEGF-VEGF receptor 2 binding in diabetic retinopathy J Mol Endocrinol 37 1 12 (Pubitemid 44288601)