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Volumn 24, Issue 3, 2009, Pages 237-244

DNA demethylation protects from cleavable complex stabilization and DNA strand breakage induced by the topoisomerase type i inhibitor camptothecin

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CAMPTOTHECIN; CYTIDINE; DNA TOPOISOMERASE; GENOMIC DNA;

EID: 66749121440     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/gep002     Document Type: Article
Times cited : (7)

References (47)
  • 2
    • 0026653420 scopus 로고
    • The essentials of DNA methylation
    • Bird, A. (1992) The essentials of DNA methylation. Cell, 70, 5-8.
    • (1992) Cell , vol.70 , pp. 5-8
    • Bird, A.1
  • 3
    • 0030014783 scopus 로고    scopus 로고
    • DNA topoisomerases
    • Wang, J. C. (1996) DNA topoisomerases. Annu. Rev. Biochem., 65, 635-692.
    • (1996) Annu. Rev. Biochem , vol.65 , pp. 635-692
    • Wang, J.C.1
  • 6
    • 0024592815 scopus 로고
    • Biochemical basis for the interactions of type I and type II topoisomerases with DNA
    • Osheroff, N. (1989) Biochemical basis for the interactions of type I and type II topoisomerases with DNA. Pharmacol. Ther., 41, 223-241.
    • (1989) Pharmacol. Ther , vol.41 , pp. 223-241
    • Osheroff, N.1
  • 7
    • 0032189945 scopus 로고    scopus 로고
    • DNA sequence selectivity of topoisomerases and topoisomerase poisons
    • Capranico, G. and Binaschi, M. (1998) DNA sequence selectivity of topoisomerases and topoisomerase poisons. Biochim. Biophys. Acta, 1400, 185-194.
    • (1998) Biochim. Biophys. Acta , vol.1400 , pp. 185-194
    • Capranico, G.1    Binaschi, M.2
  • 8
    • 0021955171 scopus 로고
    • Quantitation of eukaryotic topoisomerase I reactivity with DNA. Preferential cleavage of supercoiled DNA
    • Muller, M. T. (1985) Quantitation of eukaryotic topoisomerase I reactivity with DNA. Preferential cleavage of supercoiled DNA. Biochim. Biophys. Acta, 20, 263-267.
    • (1985) Biochim. Biophys. Acta , vol.20 , pp. 263-267
    • Muller, M.T.1
  • 9
    • 0031003701 scopus 로고    scopus 로고
    • Effects of uracil incorporation, DNA mismatches, and abasic sites on cleavage and religation activities of mammalian topoisomerase I
    • Pourquier, P., Ueng, L.-M., Kohlhagen, G., Mazumder, A., Gupta, M., Kohn, K. W. and Pommier, Y. (1997) Effects of uracil incorporation, DNA mismatches, and abasic sites on cleavage and religation activities of mammalian topoisomerase I. J. Biol. Chem., 272, 7792-7796.
    • (1997) J. Biol. Chem , vol.272 , pp. 7792-7796
    • Pourquier, P.1    Ueng, L.-M.2    Kohlhagen, G.3    Mazumder, A.4    Gupta, M.5    Kohn, K.W.6    Pommier, Y.7
  • 10
    • 0032571493 scopus 로고    scopus 로고
    • Substitution of 5-methylcytosines for cytosines enhances the stability of topoisomerase I-DNA complexes and modulates the sequence selectivity of camptothecin-induced DNA cleavage
    • Carrasco, C., Waring, M. J. and Bailly, C. (1998) Substitution of 5-methylcytosines for cytosines enhances the stability of topoisomerase I-DNA complexes and modulates the sequence selectivity of camptothecin-induced DNA cleavage. FEBS Lett., 425, 337-340.
    • (1998) FEBS Lett , vol.425 , pp. 337-340
    • Carrasco, C.1    Waring, M.J.2    Bailly, C.3
  • 11
    • 37149000618 scopus 로고    scopus 로고
    • Protection of halogenated DNA from strand breakage and sister-chromatid exchange induced by the topoisomerase I inhibitor camptothecin
    • Orta, M. L., Mateos, S., Cantero, G., Wolff, L. J. and Cortés, F. (2008) Protection of halogenated DNA from strand breakage and sister-chromatid exchange induced by the topoisomerase I inhibitor camptothecin. Mutat. Res., 637, 40-48.
    • (2008) Mutat. Res , vol.637 , pp. 40-48
    • Orta, M.L.1    Mateos, S.2    Cantero, G.3    Wolff, L.J.4    Cortés, F.5
  • 12
    • 0000163138 scopus 로고    scopus 로고
    • Gel electrophoresis of DNA
    • Irwin, N, Ford, N, Nolan, C. and Ferguson, M, eds, Cold Spring Harbor Laboratory, New York
    • Sambrook, J., Fritsch, E. F. and Maniatis, T. (2003) Gel electrophoresis of DNA. In: Irwin, N., Ford, N., Nolan, C. and Ferguson, M. (eds), Molecular Cloning. A Laboratory Manual. Cold Spring Harbor Laboratory, New York.
    • (2003) Molecular Cloning. A Laboratory Manual
    • Sambrook, J.1    Fritsch, E.F.2    Maniatis, T.3
  • 13
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254.
    • (1976) Anal. Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 14
    • 0023713928 scopus 로고
    • DNase I hypersensitivity is independent of endogenous topoisomerase II activity during chicken erythrocyte differentiation
    • Muller, M. T. and Mehta, V. B. (1988) DNase I hypersensitivity is independent of endogenous topoisomerase II activity during chicken erythrocyte differentiation. Mol. Cell. Biol., 8, 3661-3669.
    • (1988) Mol. Cell. Biol , vol.8 , pp. 3661-3669
    • Muller, M.T.1    Mehta, V.B.2
  • 15
    • 0029041130 scopus 로고
    • Analysis of topoisomerase I/DNA complexes in patients administered topothecan
    • Subramanian, D., Kraut, E., Staubus, A., Young, D. C. and Muller, M. T. (1995) Analysis of topoisomerase I/DNA complexes in patients administered topothecan. Cancer Res., 55, 2097-2103.
    • (1995) Cancer Res , vol.55 , pp. 2097-2103
    • Subramanian, D.1    Kraut, E.2    Staubus, A.3    Young, D.C.4    Muller, M.T.5
  • 16
    • 25844472609 scopus 로고    scopus 로고
    • The DNA demethylating 5-azaC induces endoreduplication in cultured Chinese hamster cells
    • Mateos, S., Domínguez, I., Pastor, N., Cantero, G. and Cortés, F. (2005) The DNA demethylating 5-azaC induces endoreduplication in cultured Chinese hamster cells. Mutat. Res., 578, 33-42.
    • (2005) Mutat. Res , vol.578 , pp. 33-42
    • Mateos, S.1    Domínguez, I.2    Pastor, N.3    Cantero, G.4    Cortés, F.5
  • 17
    • 0023919963 scopus 로고
    • A simple technique for quantification of low levels of DNA damage in individual cells
    • Singh, N. P., McCoy, M. T., Tice, R. R. and Schneider, E. L. (1988) A simple technique for quantification of low levels of DNA damage in individual cells. Exp. Cell Res., 175, 184-191.
    • (1988) Exp. Cell Res , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 18
    • 0028918375 scopus 로고
    • The comet assay: A comprehensive review
    • Fairbairn, D. W., Olive, P. L. and O'Neill, K. L. (1995) The comet assay: a comprehensive review. Mutat. Res., 339, 37-59.
    • (1995) Mutat. Res , vol.339 , pp. 37-59
    • Fairbairn, D.W.1    Olive, P.L.2    O'Neill, K.L.3
  • 19
    • 0025305451 scopus 로고
    • Detection of etoposide resistance by measuring DNA damage in individual Chinese hamster cells
    • Olive, P. L., Banath, J. P. and Durand, R. E. (1990) Detection of etoposide resistance by measuring DNA damage in individual Chinese hamster cells. J. Natl Cancer Inst., 82, 779-783.
    • (1990) J. Natl Cancer Inst , vol.82 , pp. 779-783
    • Olive, P.L.1    Banath, J.P.2    Durand, R.E.3
  • 20
    • 0018860957 scopus 로고
    • Cellular differentiation, cytidine analogs and DNA methylation
    • Jones, P. A. and Taylor, S. M. (1980) Cellular differentiation, cytidine analogs and DNA methylation. Cell, 20, 85-93.
    • (1980) Cell , vol.20 , pp. 85-93
    • Jones, P.A.1    Taylor, S.M.2
  • 22
    • 0020955602 scopus 로고
    • Induction of chromosome decondensation, sister-chromatid exchanges and endoreduplications by 5-azacytidine, an inhibitor of DNA methylation
    • Hori, T. A. (1983) Induction of chromosome decondensation, sister-chromatid exchanges and endoreduplications by 5-azacytidine, an inhibitor of DNA methylation. Mutat. Res., 121, 47-52.
    • (1983) Mutat. Res , vol.121 , pp. 47-52
    • Hori, T.A.1
  • 23
    • 0029056196 scopus 로고
    • The influence of DNA methylation on topoisomerase II activity and its possible link with genome instability in different cell lines of the Syrian hamster
    • Kirchner, S., Schiffmann, D. and Stopper, H. (1995) The influence of DNA methylation on topoisomerase II activity and its possible link with genome instability in different cell lines of the Syrian hamster. Toxicol. In Vitro, 9, 519-525.
    • (1995) Toxicol. In Vitro , vol.9 , pp. 519-525
    • Kirchner, S.1    Schiffmann, D.2    Stopper, H.3
  • 24
    • 0035835052 scopus 로고    scopus 로고
    • DNA methylation influences the decatenation activity of topoisomerase II
    • Boos, G. and Stopper, H. (2001) DNA methylation influences the decatenation activity of topoisomerase II. Int. J. Biol. Macrom., 28, 103-106.
    • (2001) Int. J. Biol. Macrom , vol.28 , pp. 103-106
    • Boos, G.1    Stopper, H.2
  • 25
    • 0037219218 scopus 로고    scopus 로고
    • Roles of DNA topoisomerases in chromosome segregation and mitosis
    • Cortés, F., Pastor, N., Mateos, S. and Dominguez, I. (2003) Roles of DNA topoisomerases in chromosome segregation and mitosis. Rev. Mutat. Res., 543, 59-66.
    • (2003) Rev. Mutat. Res , vol.543 , pp. 59-66
    • Cortés, F.1    Pastor, N.2    Mateos, S.3    Dominguez, I.4
  • 27
    • 0021760306 scopus 로고
    • Nucleotide sequence preference at rat liver and wheat germ type 1 DNA topoisomerase breakage sites in duplex SV40 DNA
    • Been, M. D., Burgess, R. R. and Champox, J. J. (1984) Nucleotide sequence preference at rat liver and wheat germ type 1 DNA topoisomerase breakage sites in duplex SV40 DNA. Nucleic Acids Res., 12, 3097-3114.
    • (1984) Nucleic Acids Res , vol.12 , pp. 3097-3114
    • Been, M.D.1    Burgess, R.R.2    Champox, J.J.3
  • 28
    • 0024592815 scopus 로고
    • Biochemical basis for the interactions of type I and type II topoisomerases with DNA
    • Osheroff, N. (1989) Biochemical basis for the interactions of type I and type II topoisomerases with DNA. Pharmacol. Ther., 41, 223-241.
    • (1989) Pharmacol. Ther , vol.41 , pp. 223-241
    • Osheroff, N.1
  • 29
    • 0020489806 scopus 로고
    • Recognition sites of eukaryotic DNA topoisomerase I: DNA nucleotide sequencing analysis of topo I cleavage sites on SV40 DNA
    • Edwards, K. A., Halligan, B. D., Davis, J. L., Nivera, N. D. and Liu, L. F. (1982) Recognition sites of eukaryotic DNA topoisomerase I: DNA nucleotide sequencing analysis of topo I cleavage sites on SV40 DNA. Nucleic Acids Res., 10, 2565-2576.
    • (1982) Nucleic Acids Res , vol.10 , pp. 2565-2576
    • Edwards, K.A.1    Halligan, B.D.2    Davis, J.L.3    Nivera, N.D.4    Liu, L.F.5
  • 30
    • 0022369729 scopus 로고
    • A high affinity topoisomerase I binding sequence is clustered at DNAase I hypersensitive sites in Tetrahymena r-chromatin
    • Bonven, B. J., Gocke, E. and Westergaard, O. (1985) A high affinity topoisomerase I binding sequence is clustered at DNAase I hypersensitive sites in Tetrahymena r-chromatin. Cell, 41, 541-551.
    • (1985) Cell , vol.41 , pp. 541-551
    • Bonven, B.J.1    Gocke, E.2    Westergaard, O.3
  • 31
    • 0034446542 scopus 로고    scopus 로고
    • DNA methylation, nuclear structure, gene expression and cancer
    • Leonhardt, H. and Cardoso, M. C. (2000) DNA methylation, nuclear structure, gene expression and cancer. J. Cell Biochem., 35 (Suppl.), 78-83.
    • (2000) J. Cell Biochem , vol.35 , Issue.SUPPL. , pp. 78-83
    • Leonhardt, H.1    Cardoso, M.C.2
  • 32
    • 0026526740 scopus 로고
    • In vivo topoisomerase II cleavage of the Drosophila histone and satellite III repeats: DNA sequence and structural characteristics
    • Käs, E. and Laemli, U. K. (1992) In vivo topoisomerase II cleavage of the Drosophila histone and satellite III repeats: DNA sequence and structural characteristics. EMBO J., 11, 705-716.
    • (1992) EMBO J , vol.11 , pp. 705-716
    • Käs, E.1    Laemli, U.K.2
  • 33
    • 36949016699 scopus 로고    scopus 로고
    • Alterations of DNA methylation associated with abnormalities of DNA methyltransferases in human cancers during transition from a precancerous to a malignant state
    • Kanai, Y. and Hirohashi, S. (2007) Alterations of DNA methylation associated with abnormalities of DNA methyltransferases in human cancers during transition from a precancerous to a malignant state. Carcinogenesis, 28, 2434-2442.
    • (2007) Carcinogenesis , vol.28 , pp. 2434-2442
    • Kanai, Y.1    Hirohashi, S.2
  • 34
    • 0037068378 scopus 로고    scopus 로고
    • DNA methylation and cancer
    • Jones, P. A. (2002) DNA methylation and cancer. Oncogene, 21, 5358-5360.
    • (2002) Oncogene , vol.21 , pp. 5358-5360
    • Jones, P.A.1
  • 35
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones, P. A. and Baylin, S. B. (2002) The fundamental role of epigenetic events in cancer. Nat. Rev. Genet., 3, 415-428.
    • (2002) Nat. Rev. Genet , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 36
    • 14644396228 scopus 로고    scopus 로고
    • Detection and interpretation of altered methylation patterns in cancer cells
    • Ushijima, T. (2005) Detection and interpretation of altered methylation patterns in cancer cells. Nat. Rev. Cancer, 5, 223-231.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 223-231
    • Ushijima, T.1
  • 37
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?
    • Baylin, S. B. and Ohm, J. E. (2006) Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction? Nat. Rev. Cancer, 6, 107-116.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 38
    • 33749070191 scopus 로고    scopus 로고
    • Targeting DNA methylation in cancer
    • Szyf, M. (2006) Targeting DNA methylation in cancer. Bull. Cancer, 93, 961-972.
    • (2006) Bull. Cancer , vol.93 , pp. 961-972
    • Szyf, M.1
  • 39
    • 33744918070 scopus 로고    scopus 로고
    • DNA methylation changes after 5-aza-2'-deoxycytidine therapy in patients with leukaemia
    • Yang, A. S., Doshi, K. D., Choi, S. W. et al. (2006) DNA methylation changes after 5-aza-2'-deoxycytidine therapy in patients with leukaemia. Cancer Res., 66, 5495-5503.
    • (2006) Cancer Res , vol.66 , pp. 5495-5503
    • Yang, A.S.1    Doshi, K.D.2    Choi, S.W.3
  • 40
    • 34548585368 scopus 로고    scopus 로고
    • The use of hypomethylating agents in the treatment of hematologic malignancies
    • Kishlinger, J. E. and Godley, L. A. (2007) The use of hypomethylating agents in the treatment of hematologic malignancies. Leuk. Lymphoma, 48, 1676-1695.
    • (2007) Leuk. Lymphoma , vol.48 , pp. 1676-1695
    • Kishlinger, J.E.1    Godley, L.A.2
  • 41
    • 34547799171 scopus 로고    scopus 로고
    • DNA methyltransferases as targets for cancer therapy
    • Goshal, K. and Bai, S. (2007) DNA methyltransferases as targets for cancer therapy. Drugs Today, 43, 395-422.
    • (2007) Drugs Today , vol.43 , pp. 395-422
    • Goshal, K.1    Bai, S.2
  • 42
    • 43749117734 scopus 로고    scopus 로고
    • A phase II study of 5-azacytidine for patients with primary and post-essential thrombocythemia/polycytemia vera myelofibrosis
    • Quintás-Cardama, A., Tong, W., Kantarjian, H. et al. (2008) A phase II study of 5-azacytidine for patients with primary and post-essential thrombocythemia/polycytemia vera myelofibrosis. Leukemia, 22, 965-970.
    • (2008) Leukemia , vol.22 , pp. 965-970
    • Quintás-Cardama, A.1    Tong, W.2    Kantarjian, H.3
  • 43
    • 38949120072 scopus 로고    scopus 로고
    • Treatment strategies in myelodysplastic syndromes
    • Atallah, E. and Garcia-Manero, G. (2008) Treatment strategies in myelodysplastic syndromes. Cancer Invest., 26, 208-216.
    • (2008) Cancer Invest , vol.26 , pp. 208-216
    • Atallah, E.1    Garcia-Manero, G.2
  • 44
    • 0022340594 scopus 로고
    • Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
    • Hsiang, Y. H., Hertzberg, R., Hecht, S. and Liu, L. F. (1985) Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J. Biol. Chem., 260, 14873-14878.
    • (1985) J. Biol. Chem , vol.260 , pp. 14873-14878
    • Hsiang, Y.H.1    Hertzberg, R.2    Hecht, S.3    Liu, L.F.4
  • 45
    • 19144361907 scopus 로고    scopus 로고
    • Camptothecin and its analogues: A review on their chemotherapeutic potential
    • Sriram, D., Yogeeswari, P., Thirumurugan, R. and Bal, T. R. (2005) Camptothecin and its analogues: a review on their chemotherapeutic potential. Nat. Prod. Res., 19, 393-412.
    • (2005) Nat. Prod. Res , vol.19 , pp. 393-412
    • Sriram, D.1    Yogeeswari, P.2    Thirumurugan, R.3    Bal, T.R.4
  • 47
    • 33749034730 scopus 로고    scopus 로고
    • Topoisomerase I inhibitors: Camptothecins and beyond
    • Pommier, Y. (2006) Topoisomerase I inhibitors: camptothecins and beyond. Nat. Rev. Cancer, 6, 789-802.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 789-802
    • Pommier, Y.1


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