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Volumn 425, Issue 2, 1998, Pages 337-340
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Substitution of 5-methylcytosines for cytosines enhances the stability of topoisomerase I-DNA complexes and modulates the sequence selectivity of camptothecin-induced DNA cleavage
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Author keywords
Camptothecin; Methylcytosine; Topoisomerase
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Indexed keywords
CAMPTOTHECIN;
DNA FRAGMENT;
DNA TOPOISOMERASE;
RESTRICTION ENDONUCLEASE;
ARTICLE;
DNA BINDING;
DNA CLEAVAGE;
IN VITRO STUDY;
INTERCALATION COMPLEX;
NUCLEIC ACID BASE SUBSTITUTION;
PRIORITY JOURNAL;
RESTRICTION FRAGMENT;
5-METHYLCYTOSINE;
BASE SEQUENCE;
CAMPTOTHECIN;
CYTOSINE;
DNA;
DNA TOPOISOMERASES, TYPE I;
HUMANS;
MOLECULAR SEQUENCE DATA;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 0032571493
PISSN: 00145793
EISSN: None
Source Type: Journal
DOI: 10.1016/S0014-5793(98)00259-2 Document Type: Article |
Times cited : (3)
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References (13)
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