Expression of CD34 α-smooth muscle actin and transforming growth factor-β1 in squamous intraepithelial lesions and squamous cell carcinoma of the cervix

Journal of International Medical Research

Volumn 37, Issue 2, 2009, Pages 446-454

  Li, Q ^a,b   Huang, W ^c   Zhou, Xiaojun ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b WOMEN S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^c NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Carcinoma CD34; Cervix; Intraepithelial neoplasia; Myofibroblast; Smooth muscle actin; Squamous cell; Stromal cell

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CD34 ANTIGEN; TRANSFORMING GROWTH FACTOR BETA1; ACTIN;

ADULT; AGED; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MYOFIBROBLAST; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; SQUAMOUS CELL CARCINOMA; STROMA CELL; UTERINE CERVIX CARCINOMA; UTERINE CERVIX CARCINOMA IN SITU; UTERINE CERVIX EPITHELIUM; EPITHELIUM CELL; METABOLISM; MIDDLE AGED; PATHOLOGY; SMOOTH MUSCLE FIBER; UTERINE CERVIX TUMOR;

ACTINS; ADULT; AGED; ANTIGENS, CD34; CARCINOMA, SQUAMOUS CELL; CERVICAL INTRAEPITHELIAL NEOPLASIA; EPITHELIAL CELLS; FEMALE; HUMANS; MIDDLE AGED; MYOCYTES, SMOOTH MUSCLE; STROMAL CELLS; TRANSFORMING GROWTH FACTOR BETA1; UTERINE CERVICAL NEOPLASMS;

EID: 66649117253     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323000903700220     Document Type: Article

References (29)

1. Noel A, Foidart JM: The role of stroma in breast carcinoma growth in vivo. J Mammary Gland Biol Neoplasia 1998; 3: 215-225.
2. Ronnov-Jessen L, Petersen OW, Bissell MJ: Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction. Physiol Rev 1996; 76: 69-125.
3. Tuxhorn JA, Ayala GE, Rowley DR: Reactive stroma in prostate cancer progression. J Urol 2001; 166: 2472-2483.
4. De Wever O, Mareel M: Role of tissue stroma in cancer cell invasion. J Pathol 2003; 200: 429-447.
5. Ohtani H: Stromal reaction in cancer tissue: pathophysiologic significance of the expression of matrix degrading enzymes in relation to matrix turnover and immune/inflammatory reaction. Pathol Int 1998; 48: 1-9.
6. Pupa SM, Menard S, Forti S, et al: New insights into the role of extracellular matrix during tumour onset and progression. J Cell Physiol 2002; 192: 259-267.
7. Katsenelson NS, Shurin GV, Bykovskala SN, et al: human small cell lung carcinoma and carcinoid tumor regulate dendritic cell maturation and function. Mod Pathol 2001; 14: 40-45.
8. + cells in human intestine are fibroblats adjacent to, but distinct from, intestinal cells of Cajal. Lab. Invest. 1999; 79: 59-65.
9. Nakayama H, Enzan H, Miyazaki E, et al: Differential expression of CD34 in normal colorectal tissue, peritumoral inflammatory tissue, and tumour stroma. J Clin Pathol 2000; 53: 626-629.
10. + fibrocytes in ductal adenocarcinoma of the pancreas chronic pancreatitis and normal pancreatic parenchyma. Virchows Arch 2002; 440: 128-133.
11. + fibrocytes in invasive ductal carcinoma, ductal carcinoma in situ, an benign breast lesions. Virchows Arch 2002; 440: 298-303.
12. + fibrocytes in normal cervical stroma, cervical intraepithelial neplasia III, and invasive squamous cell carcinoma of the cervix uteri. Vichows Arch 2002; 441: 564-568.
13. Powell DW, Mifflin RC, Valentich JD, et al: Myofibroblasts. I. Paracrine cells important in health and disease. Am J Physiol 1999; 277: C1-C19.
14. Powell DW, Mifflin RC, Valentich JD, et al: Myofibroblasts. I. Paracrine cells important in health and disease. Am J Physiol 1999; 277: C183-C201.
15. Emura M, Ochiai A, Horino M: Development of myofibroblasts from human bone marrow mesenchymal stem cells cocultured with human colon carcinoma cells and TGF beta 1. In Vitro Cell Dev Biol Anim 2000; 36: 77-80.
16. Martin M, Pujuguet P, Martin F: Role of stroml myofibroblasts infiltrating colon cancer in tumour invasion. Pathol Res Pract 1996; 192: 712-717.
17. Liotta LA, Kohn EC: The microenvironment of the tumour-host interface. Nature 2001; 411: 375-379.
18. Soma L, Livolsi VA, Baloch ZW: Dendritic interstitial and myofibroblastic cells at the border of salivary gland tumors. Arch Pathol Lab Med 2001; 125: 232-236.
19. + fibrocytes, smooth muscle antigen-positive myofibroblasts, and CD117 expression in the stroma of invasive squamous cell carcinoma of the oral cavity, pharynz and larynx. Virchows Arch 2004; 444: 231-234.
20. Chauhan H, Abraham A, Philips JR, et al: There is more than one kind of myofibroblasts: analysis of CD34 expression in benign, in situ and invasive breast lesions. J clin Pathol 2003; 56: 271-276.
21. Kojc N, Zidar N, Vodopivec B, et al: Expression of CD34, α-smooth muscle actin, and transforming growth factor β1 in squamous intraepithelial lesions and squamous cell carcinoma of the larynx and hypopharynx. Hum Pathol 2005; 36: 16-21.
22. Nakayama H, Enzan H, Miyazaki E, et al: Differentail expression of CD34 in normal colorectal tissue, peritumoral inflammatory tissue, and tumours stroma. J. clin Pathol 2000; 53: 626-629.
23. Yen TWF, Aardal NP, Bronner MP, et al: Myofibroblasts are responsible for the desmoplastic reaction surrounding human pancreatic carcinomas. Surgery 2002; 131: 129-134.
24. Cintorino M, Bellizi de Marco E, Leoncini P, et al: Expression of alpha-smooth-muscle actin in stromal cells of the uterine cervix during epithelial neoplastic changes. Int J Cancer 1991; 47: 843-846.
25. + fibrocytes in tubular carcinomas and radial scars of the breast. Virchows Arch 2003; 443: 536-540.
26. Tuan TLO, Nichter LS: The molecular basis of keloid and hypertropic scar formation. Mol Med Today 1998; 4: 19-24.
27. Hagedorn H, Sauer U, Schleicher E, et al: Expression of TGF-β1 protein and mRNA and the effect on the tissue remodeling in laryngeal carcinomas. Anticancer Res 1999; 19: 4265-4275.
28. Rowley DR: What a might a stromal response mean to prostate cancer progression? Cancer Metastasis Rev 1999; 17: 411-419.
29. Pasche B: Role of transforming growth factor beta in cancer. J Cell Physiol 2001; 186: 153-168.