Hypermethylated genes as biomarkers of cancer in women with pathologic nipple discharge

Clinical Cancer Research

Volumn 15, Issue 11, 2009, Pages 3802-3811

  Fackler, Mary Jo ^a   Rivers, Aeisha ^b   Wei, Wen Teo ^a   Mangat, Amrit ^b   Taylor, Evangeline ^a   Zhang, Zhe ^a   Goodman, Steve ^a   Argani, Pedram ^a   Nayar, Ritu ^b   Susnik, Barbara ^b   Sukumar, Saraswati ^a,c   Khan, Seema A ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER;

ADULT; AGED; APC 1 GENE; ARTICLE; BREAST DISCHARGE; CDH1 GENE; CLINICAL ARTICLE; CYCLIN D2 GENE; CYTOLOGY; DIAGNOSTIC PROCEDURE; DIAGNOSTIC VALUE; DNA METHYLATION; ER A GENE; FEMALE; GENE; HIN 1 GENE; HISTOPATHOLOGY; HUMAN; INTRADUCTAL CARCINOMA; ONCOGENE; P 16 GENE; PAPILLOMA; POLYMERASE CHAIN REACTION; PREDICTION; PRIORITY JOURNAL; PROMOTER REGION; RAR BETA GENE; RASSF 1A GENE; TWIST 1 GENE;

ADULT; AGED; BREAST DISEASES; BREAST NEOPLASMS; CARCINOMA IN SITU; CARCINOMA, DUCTAL, BREAST; CYTOKINES; DIAGNOSIS, DIFFERENTIAL; DNA METHYLATION; ENDOSCOPY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MAMMARY GLANDS, HUMAN; MIDDLE AGED; NIPPLES; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEINS; TWIST TRANSCRIPTION FACTOR;

EID: 66649087110     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-08-1981     Document Type: Article

References (27)

1. Dixon JM, Mansel RE. ABC of breast diseases. Symptoms assessment and guidelines for referral. BMJ 1994;309:722-726
2. Gulay H, Bora S, Kilicturgay S, Hamaloglu E, Goksel HA. Management of nipple discharge. J Am Coll Surg 1994;178:471-474 (Pubitemid 24141502)
3. Dawes LG, Bowen C, Venta LA, Morrow M. Ductography for nipple discharge: no replacement for ductal excision. Surgery 1998;124:685-691
4. Cabioglu N, Hunt KK, Singletary SE, et al. Surgical decision making and factors determining a diagnosis of breast carcinoma in women presenting with nipple discharge. J Am Coll Surg 2003;196:354-364 (Pubitemid 36343635)
5. Moncrief RM, Nayar R, Diaz LK, Staradub VL, Morrow M, Khan SA. A comparison of ductoscopy- guided and conventional surgical excision in women with pathologic nipple discharge. Ann Surg 2005;241:575-581 (Pubitemid 40397304)
6. Liu GY, Lu JS, Shen KW, et al. Fiberoptic ductoscopy combined with cytology testing in the patients of pathologic nipple discharge. Breast Cancer Res Treat 2007.
7. Shen KW, Wu J, Lu JS, et al. Fiberoptic ductoscopy for patients with nipple discharge. Cancer 2000;89:1512-1519
8. Gray RJ, Pockaj BA, Karstaedt PJ. Navigating murky waters: a modern treatment algorithm for nipple discharge. Am J Surg 2007;194:850-4, discussion 4-5. (Pubitemid 350086539)
9. Sauter ER, Ehya H, Klein-Szanto AJ, Wagner-Mann C, MacGibbon B. Fiberoptic ductoscopy findings in women with and without pathologic nipple discharge. Cancer 2005;103:914-921 (Pubitemid 40270068)
10. Morrogh M, Morris EA, Liberman L, Borgen PI, King TA. The predictive value of ductography and magnetic resonance imaging in the management of nipple discharge. Ann Surg Oncol 2007;14:3369-3377 (Pubitemid 350160109)
11. Dua RS, Isacke CM, Gui GP. The intraductal approach to breast cancer biomarker discovery. J Clin Oncol 2006;24:1209-1216 (Pubitemid 46638820)
12. Sauter ER, Ehya H, Schlatter L, MacGibbon B. Ductoscopic cytology to detect breast cancer. Cancer J 2004;10:33-41, discussion 15-16 (Pubitemid 44313572)
13. Dooley WC, Francescatti D, Clark L, Webber G. Office-based breast ductoscopy for diagnosis. Am J Surg 2004;188:415-418 (Pubitemid 39330548)
14. Hunerbein M, Raubach M, Gebauer B, Schneider W, Schlag PM. Ductoscopy and intraductal vacuum assisted biopsy in women with pathologic nipple discharge. Breast Cancer Res Treat 2006;99:301-307 (Pubitemid 44337922)
15. Al Sarakbi W, Salhab M, Mokbel K. Does mammary ductoscopy have a role in clinical practice?. Int Semin Surg Oncol 2006;3:16. (Pubitemid 44151461)
16. Danforth DN, Jr., Abati A, Filie A, et al. Combined breast ductal lavage and ductal endoscopy for the evaluation of the high-risk breast: a feasibility study. J Surg Oncol 2006;94:555-564 (Pubitemid 44851916)
17. Valdes EK, Boolbol SK, Cohen JM, Balassanian R, Feldman SM. Clinical experience with mammary ductoscopy. Ann Surg Oncol 2006.
18. Okazaki A, Okazaki M, Asaishi K, et al. Fiberoptic ductoscopy of the breast: a new diagnostic procedure for nipple discharge. Jpn J Clin Oncol 1991;21:188-193
19. Murata S, Kominsky SL, Vali M, et al. Ductal access for prevention and therapy of mammary tumors. Cancer Res 2006;66:638-645 (Pubitemid 43165923)
20. Widschwendter M, Jones PA. DNA methylation and breast carcinogenesis. Oncogene 2002;21:5462-5482 (Pubitemid 34983482)
21. Fackler MJ, Malone K, Zhang Z, et al. Quantitative multiplex methylation-specific PCR analysis doubles detection of tumor cells in breast ductal fluid. Clin Cancer Res 2006;12:3306-3310 (Pubitemid 43910873)
22. Khan SA, Wiley EL, Rodriguez N, et al. Ductal lavage findings in women with known breast cancer undergoing mastectomy. J Natl Cancer Inst 2004;96:1510-1517 (Pubitemid 39445532)
23. Fackler MJ, McVeighM, Mehrotra J, et al. Quantitative multiplex methylation-specific PCR assay for the detection of promoter hypermethylation in multiple genes in breast cancer. Cancer Res 2004;64:4442-4452 (Pubitemid 38856915)
24. Evron E, Dooley WC, Umbricht CB, et al. Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR. Lancet 2001;357:1335-1336 (Pubitemid 32441534)
25. Locke I, Kote-Jarai Z, Fackler MJ, et al. Gene promoter hypermethylation in ductal lavage fluid from healthy BRCA gene mutation carriers and mutation-negative controls. Breast Cancer Res 2007;9:R20. (Pubitemid 350215141)
26. Euhus DM, Bu D, Ashfaq R, et al. Atypia and DNA methylation in nipple duct lavage in relation to predicted breast cancer risk. Cancer Epidemiol Biomarkers Prev 2007;16:1812-1821 (Pubitemid 47450511)
27. Markopoulos C, Mantas D, Kouskos E, et al. Surgical management of nipple discharge. Eur J Gynaecol Oncol 2006;27:275-278 (Pubitemid 43953426)