Inhibition of STAT5 induces G1 cell cycle arrest and reduces tumor cell invasion in human colorectal cancer cells

Laboratory Investigation

Volumn 89, Issue 6, 2009, Pages 717-725

  Xiong, Hua ^a   Su, Wen Yu ^a   Liang, Qin Chuan ^b   Zhang, Zhi Gang ^a   Chen, Hui Min ^a   Du, Wan ^a   Chen, Ying Xuan ^a   Fang, Jing Yuan ^a,c  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Colorectal cancer; Signal transduction; STAT5; Tumor related gene; Tumorigenesis

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN DEPENDENT KINASE INHIBITOR 2A; FOCAL ADHESION KINASE; MATRIX METALLOPROTEINASE; METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BCL 2; PROTEIN P44; SMALL INTERFERING RNA; STAT5 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; UVOMORULIN; VASCULOTROPIN;

ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INVASION; CARCINOGENESIS; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL INVASION; CELL MIGRATION; CELL NUCLEUS INCLUSION BODY; COLON ADENOCARCINOMA; COLON ADENOMA; COLON MUCOSA; COLORECTAL CANCER; CONTROLLED STUDY; CYTOPLASM; EPITHELIUM CELL; GENE ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HYPOTHESIS; IMMUNOHISTOCHEMISTRY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPREGULATION;

EID: 66549120065     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2009.11     Document Type: Article

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