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Volumn 19, Issue 14, 1999, Pages 5750-5757

κ-Opioid tolerance and dependence in cultures of dopaminergic midbrain neurons

Author keywords

Dependence; Dopaminergic neurons; Mesencephalon; Neurotransmitter release; Primary neuronal culture; Tolerance; U69,593; opioid receptor

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; DOPAMINE; KAPPA OPIATE RECEPTOR ANTAGONIST; N METHYL N [7 (1 PYRROLIDINYL) 1 OXASPIRO[4.5]DEC 8 YL]BENZENEACETAMIDE; NORBINALTORPHIMINE; OPIATE DERIVATIVE; PERTUSSIS TOXIN; TETRODOTOXIN;

EID: 0033565855     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-14-05750.1999     Document Type: Article
Times cited : (21)

References (43)
  • 1
    • 0024430453 scopus 로고
    • Effect of chronic administration of U-50,488H on tolerance to its pharmacological actions and on multiple opioid receptors in rat brain regions and spinal cord
    • Bhargava HN, Gulati A, Ramarao P (1989) Effect of chronic administration of U-50,488H on tolerance to its pharmacological actions and on multiple opioid receptors in rat brain regions and spinal cord. J Pharmacol Exp Ther 251:21-26.
    • (1989) J Pharmacol Exp Ther , vol.251 , pp. 21-26
    • Bhargava, H.N.1    Gulati, A.2    Ramarao, P.3
  • 2
    • 0027291384 scopus 로고
    • The κ-opioid receptor agonist U50,488H induces acute physical dependence in guinea-pigs
    • Brent PJ, Chahl LA, Cantarell PA, Kavanagh C (1993) The κ-opioid receptor agonist U50,488H induces acute physical dependence in guinea-pigs. Eur J Pharmacol 241:149-156.
    • (1993) Eur J Pharmacol , vol.241 , pp. 149-156
    • Brent, P.J.1    Chahl, L.A.2    Cantarell, P.A.3    Kavanagh, C.4
  • 4
    • 0242421370 scopus 로고
    • Opioid receptor reserve in normal and morphine-tolerant guinea pig ileum myenteric plexus
    • Chavkin C, Goldstein A (1984) Opioid receptor reserve in normal and morphine-tolerant guinea pig ileum myenteric plexus. Proc Natl Acad Sci USA 81:7253-7257.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 7253-7257
    • Chavkin, C.1    Goldstein, A.2
  • 5
    • 0028931471 scopus 로고
    • Neuronal adaptation to amphetamine and dopamine: Molecular mechanisms of prodynorphin gene regulation in rat striatum
    • Cole RL, Konradi C, Douglass J, Hyman SE (1995) Neuronal adaptation to amphetamine and dopamine: molecular mechanisms of prodynorphin gene regulation in rat striatum. Neuron 14:813-823.
    • (1995) Neuron , vol.14 , pp. 813-823
    • Cole, R.L.1    Konradi, C.2    Douglass, J.3    Hyman, S.E.4
  • 6
    • 0020674860 scopus 로고
    • Comparison of dynorphin-selective κ receptors in mouse vas deferens and guinea pig ileum. Spare receptor fraction as a determinant of potency
    • Cox BM, Chavkin C (1983) Comparison of dynorphin-selective κ receptors in mouse vas deferens and guinea pig ileum. Spare receptor fraction as a determinant of potency. Mol Pharmacol 23:36-43.
    • (1983) Mol Pharmacol , vol.23 , pp. 36-43
    • Cox, B.M.1    Chavkin, C.2
  • 7
    • 0343933624 scopus 로고
    • Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats
    • Di Chiara G, Imperato A (1988) Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci USA 85:5274-5278.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 5274-5278
    • Di Chiara, G.1    Imperato, A.2
  • 9
    • 0030831773 scopus 로고    scopus 로고
    • Norbinaltorphimine precipitates withdrawal and excitatory amino acid release in the locus ceruleus of butorphanol-but not morphine-dependent rats
    • Feng Y, Rockhold RW, Ho IK (1997) Norbinaltorphimine precipitates withdrawal and excitatory amino acid release in the locus ceruleus of butorphanol-but not morphine-dependent rats. J Pharmacol Exp Ther 283:932-938.
    • (1997) J Pharmacol Exp Ther , vol.283 , pp. 932-938
    • Feng, Y.1    Rockhold, R.W.2    Ho, I.K.3
  • 10
    • 0029719789 scopus 로고    scopus 로고
    • Desensitization of G-protein-coupled receptors
    • 51:319
    • Freedman NJ, Lefkowitz RJ (1996) Desensitization of G-protein-coupled receptors. Recent Prog Horm Res 51:319-51:319-351.
    • (1996) Recent Prog Horm Res , vol.51 , pp. 319-351
    • Freedman, N.J.1    Lefkowitz, R.J.2
  • 11
    • 0029001901 scopus 로고
    • κ-Opioid inhibition of morphine and cocaine self-administration in rats
    • Glick SD, Maisonneuve IM, Raucci J, Archer S (1995) κ-Opioid inhibition of morphine and cocaine self-administration in rats. Brain Res 681:147-152.
    • (1995) Brain Res , vol.681 , pp. 147-152
    • Glick, S.D.1    Maisonneuve, I.M.2    Raucci, J.3    Archer, S.4
  • 12
    • 0022508497 scopus 로고
    • κ-Receptor-mediated opioid dependence in rhesus monkeys
    • Gmerek DE, Woods JH (1986) κ-Receptor-mediated opioid dependence in rhesus monkeys. Life Sci 39:987-992.
    • (1986) Life Sci , vol.39 , pp. 987-992
    • Gmerek, D.E.1    Woods, J.H.2
  • 13
    • 0023637787 scopus 로고
    • κ Opioids in rhesus monkeys. III. Dependence associated with chronic administration
    • Gmerek DE, Dykstra LA, Woods JH (1987) κ Opioids in rhesus monkeys. III. Dependence associated with chronic administration. J Pharmacol Exp Ther 242:428-436.
    • (1987) J Pharmacol Exp Ther , vol.242 , pp. 428-436
    • Gmerek, D.E.1    Dykstra, L.A.2    Woods, J.H.3
  • 14
    • 0027223531 scopus 로고
    • The κ-opioid receptor agonist U-69593 attenuates cocaine-induced behavioral sensitization in the rat
    • Heidbreder CA, Goldberg SR, Shippenberg TS (1993) The κ-opioid receptor agonist U-69593 attenuates cocaine-induced behavioral sensitization in the rat. Brain Res 616:335-338.
    • (1993) Brain Res , vol.616 , pp. 335-338
    • Heidbreder, C.A.1    Goldberg, S.R.2    Shippenberg, T.S.3
  • 16
    • 0027462309 scopus 로고
    • Molecular alterations in the neostriatum of human cocaine addicts
    • Hurd YL, Herkenham M (1993) Molecular alterations in the neostriatum of human cocaine addicts. Synapse 13:357-369.
    • (1993) Synapse , vol.13 , pp. 357-369
    • Hurd, Y.L.1    Herkenham, M.2
  • 17
    • 0029973129 scopus 로고    scopus 로고
    • Addiction to cocaine and amphetamine
    • Hyman SE (1996) Addiction to cocaine and amphetamine. Neuron 16:901-904.
    • (1996) Neuron , vol.16 , pp. 901-904
    • Hyman, S.E.1
  • 18
    • 0030999677 scopus 로고    scopus 로고
    • κ-Opioid receptor tolerance in the guinea pig hippocampus
    • Jin W, Terman GW, Chavkin C (1997) κ-Opioid receptor tolerance in the guinea pig hippocampus. J Pharmacol Exp Ther 281:123-128.
    • (1997) J Pharmacol Exp Ther , vol.281 , pp. 123-128
    • Jin, W.1    Terman, G.W.2    Chavkin, C.3
  • 19
    • 0030756351 scopus 로고    scopus 로고
    • Drug abuse: Hedonic homeostatic dysregulation
    • Koob GF, Le Moal M (1997) Drug abuse: hedonic homeostatic dysregulation. Science 278:52-58.
    • (1997) Science , vol.278 , pp. 52-58
    • Koob, G.F.1    Le Moal, M.2
  • 21
    • 0023808591 scopus 로고
    • Role of receptor regulation in opioid tolerance mechanisms
    • Loh HH, Tao PL, Smith AP (1988) Role of receptor regulation in opioid tolerance mechanisms. Synapse 2:457-462.
    • (1988) Synapse , vol.2 , pp. 457-462
    • Loh, H.H.1    Tao, P.L.2    Smith, A.P.3
  • 22
    • 0013931421 scopus 로고
    • An experimental study in the treatment of narcotic addicts with cyclazocine
    • Martin WR, Gorodetzky CW, McClane TK (1966) An experimental study in the treatment of narcotic addicts with cyclazocine. Clin Pharmacol Ther 7:455-465.
    • (1966) Clin Pharmacol Ther , vol.7 , pp. 455-465
    • Martin, W.R.1    Gorodetzky, C.W.2    McClane, T.K.3
  • 23
    • 0032437428 scopus 로고    scopus 로고
    • Effects of κ-opioid agonists on cocaine-and food-maintained responding by rhesus monkeys
    • Mello NK, Negus SS (1998) Effects of κ-opioid agonists on cocaine-and food-maintained responding by rhesus monkeys. J Pharmacol Exp Ther 286:812-824.
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 812-824
    • Mello, N.K.1    Negus, S.S.2
  • 24
    • 0030829237 scopus 로고    scopus 로고
    • Effects of chronic U-50,488H treatment on the isolated right atrium of the rat
    • Milanes MV, Rabadan JV, Laorden ML (1997) Effects of chronic U-50,488H treatment on the isolated right atrium of the rat. Neuropeptides 31:511-515.
    • (1997) Neuropeptides , vol.31 , pp. 511-515
    • Milanes, M.V.1    Rabadan, J.V.2    Laorden, M.L.3
  • 25
  • 26
    • 0030766528 scopus 로고    scopus 로고
    • Molecular and cellular basis of addiction
    • Nestler EJ, Aghajanian GK (1997) Molecular and cellular basis of addiction. Science 278:58-63.
    • (1997) Science , vol.278 , pp. 58-63
    • Nestler, E.J.1    Aghajanian, G.K.2
  • 27
    • 0025129324 scopus 로고
    • Organization and expression of the rat D2A receptor gene: Identification of alternative transcripts and a variant donor splice site
    • O'Malley KL, Mack KJ, Gandehnan KY, Todd RD (1990) Organization and expression of the rat D2A receptor gene: identification of alternative transcripts and a variant donor splice site. Biochemistry 29:1367-1371.
    • (1990) Biochemistry , vol.29 , pp. 1367-1371
    • O'Malley, K.L.1    Mack, K.J.2    Gandehnan, K.Y.3    Todd, R.D.4
  • 28
    • 0030830097 scopus 로고    scopus 로고
    • Ventilation in morphine-maintained rhesus monkeys. II. Tolerance to the antinociceptive but not the ventilatory effects of morphine
    • Paronis CA, Woods JH (1997) Ventilation in morphine-maintained rhesus monkeys. II. Tolerance to the antinociceptive but not the ventilatory effects of morphine. J Pharmacol Exp Ther 282:355-362.
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 355-362
    • Paronis, C.A.1    Woods, J.H.2
  • 29
    • 0023139286 scopus 로고
    • Binaltorphimine and nor-binaltorphimine, potent and selective κ-opioid receptor antagonists
    • Portoghese PS, Lipkowski AW, Takemori AE (1987) Binaltorphimine and nor-binaltorphimine, potent and selective κ-opioid receptor antagonists. Life Sci 40:1287-1292.
    • (1987) Life Sci , vol.40 , pp. 1287-1292
    • Portoghese, P.S.1    Lipkowski, A.W.2    Takemori, A.E.3
  • 30
    • 0028102960 scopus 로고
    • Diuretic effects, pharmacokinetics, and safety of a new centrally acting κ-opioid agonist (CI-977) in humans
    • Reece PA, Sedman AJ, Rose S, Wright DS, Dawkins R, Rajagopalan R (1994) Diuretic effects, pharmacokinetics, and safety of a new centrally acting κ-opioid agonist (CI-977) in humans. J Clin Pharmacol 34:1126-1132.
    • (1994) J Clin Pharmacol , vol.34 , pp. 1126-1132
    • Reece, P.A.1    Sedman, A.J.2    Rose, S.3    Wright, D.S.4    Dawkins, R.5    Rajagopalan, R.6
  • 31
    • 0030740849 scopus 로고    scopus 로고
    • Sensitization to the behavioral effects of cocaine: Modulation by dynorphin and κ-opioid receptor agonists
    • Shippenberg TS, Rea W (1997) Sensitization to the behavioral effects of cocaine: modulation by dynorphin and κ-opioid receptor agonists. Pharmacol Biochem Behav 57:449-455.
    • (1997) Pharmacol Biochem Behav , vol.57 , pp. 449-455
    • Shippenberg, T.S.1    Rea, W.2
  • 32
    • 0030087946 scopus 로고    scopus 로고
    • κ-Opioid receptor agonists prevent sensitization to the conditioned rewarding effects of cocaine
    • Shippenberg TS, LeFevour A, Heidbreder C (1996) κ-Opioid receptor agonists prevent sensitization to the conditioned rewarding effects of cocaine. J Pharmacol Exp Ther 276:545-554.
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 545-554
    • Shippenberg, T.S.1    LeFevour, A.2    Heidbreder, C.3
  • 34
    • 0024462220 scopus 로고
    • Cocaine selectively increases striatonigral dynorphin levels by a dopaminergic mechanism
    • Sivam SP (1989) Cocaine selectively increases striatonigral dynorphin levels by a dopaminergic mechanism. J Pharmacol Exp Ther 250:818-824.
    • (1989) J Pharmacol Exp Ther , vol.250 , pp. 818-824
    • Sivam, S.P.1
  • 36
    • 0025107375 scopus 로고
    • The effects of opioid peptides on dopamine release in the nucleus accumbens: An in vivo microdialysis study
    • Spanagel R, Herz A, Shippenberg TS (1990) The effects of opioid peptides on dopamine release in the nucleus accumbens: an in vivo microdialysis study. J Neurochem 55:1734-1740.
    • (1990) J Neurochem , vol.55 , pp. 1734-1740
    • Spanagel, R.1    Herz, A.2    Shippenberg, T.S.3
  • 37
    • 0026559951 scopus 로고
    • Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway
    • Spanagel R, Herz A, Shippenberg TS (1992) Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway. Proc Natl Acad Sci USA 89:2046-2050.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 2046-2050
    • Spanagel, R.1    Herz, A.2    Shippenberg, T.S.3
  • 38
    • 0027327238 scopus 로고
    • "Binge" cocaine administration induces a sustained increase of prodynorphin mRNA in rat caudate-putamen
    • Spangler R, Unterwald EM, Kreek MJ (1993) "Binge" cocaine administration induces a sustained increase of prodynorphin mRNA in rat caudate-putamen. Brain Res Mol Brain Res 19:323-327.
    • (1993) Brain Res Mol Brain Res , vol.19 , pp. 323-327
    • Spangler, R.1    Unterwald, E.M.2    Kreek, M.J.3
  • 39
    • 0030612008 scopus 로고    scopus 로고
    • κ2-Opioid receptors in limbic areas of the human brain are upregulated by cocaine in fatal overdose victims
    • Staley JK, Rothman RB, Rice KC, Partilla J, Mash DC (1997) κ2-Opioid receptors in limbic areas of the human brain are upregulated by cocaine in fatal overdose victims. J Neurosci 17:8225-8233.
    • (1997) J Neurosci , vol.17 , pp. 8225-8233
    • Staley, J.K.1    Rothman, R.B.2    Rice, K.C.3    Partilla, J.4    Mash, D.C.5
  • 40
    • 0027143879 scopus 로고
    • Cocaine-induced c-fos messenger RNA is inversely related to dynorphin expression in striatum
    • Steiner H, Gerfen CR (1993) Cocaine-induced c-fos messenger RNA is inversely related to dynorphin expression in striatum. J Neurosci 13:5066-5081.
    • (1993) J Neurosci , vol.13 , pp. 5066-5081
    • Steiner, H.1    Gerfen, C.R.2
  • 41
    • 0028110978 scopus 로고
    • Repeated cocaine administration upregulates κ and μ, but not δ, opioid receptors
    • Unterwald EM, Rubenfeld JM, Kreek MJ (1994) Repeated cocaine administration upregulates κ and μ, but not δ, opioid receptors. Neuro-Report 5:1613-1616.
    • (1994) Neuro-Report , vol.5 , pp. 1613-1616
    • Unterwald, E.M.1    Rubenfeld, J.M.2    Kreek, M.J.3
  • 42
    • 0029925071 scopus 로고    scopus 로고
    • Synaptic regulation of mesocorticolimbic dopamine neurons
    • 405-36
    • White FJ (1996) Synaptic regulation of mesocorticolimbic dopamine neurons. Annu Rev Neurosci 19:405-36:405-436.
    • (1996) Annu Rev Neurosci , vol.19 , pp. 405-436
    • White, F.J.1
  • 43
    • 0029888444 scopus 로고    scopus 로고
    • Neurobiology of addiction
    • Wise RA (1996) Neurobiology of addiction. Curr Opin Neurobiol 6:243-251.
    • (1996) Curr Opin Neurobiol , vol.6 , pp. 243-251
    • Wise, R.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.