Identification of migR, a regulatory element of the Francisella tularensis live vaccine strain iglABCD virulence operon required for normal replication and trafficking in macrophages

Infection and Immunity

Volumn 77, Issue 6, 2009, Pages 2517-2529

  Buchan, Blake W ^a   McCaffrey, Ramona L ^a,b   Lindemann, Stephen R ^a   Allen, Lee Ann H ^a,b   Jones, Bradley D ^a  

^a UNIVERSITY OF IOWA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CATHEPSIN; FERRIC UPTAKE REGULATOR; IRON; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MACROPHAGE INTRACELLULAR GROWTH REGULATOR; MUTANT PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CELL LINE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; EPITHELIUM CELL; FRANCISELLA TULARENSIS; GENE CONTROL; GENE DISRUPTION; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GROWTH REGULATION; MACROPHAGE; NEUTROPHIL; NONHUMAN; OPERON; OXIDATIVE STRESS; PHAGOLYSOSOME; PHAGOSOME; PRIORITY JOURNAL; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; REGULATOR GENE; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION REGULATION; ADULT; AMINO ACID SUBSTITUTION; CELL CULTURE; GENE EXPRESSION PROFILING; GENETICS; HUMAN; IMMUNOLOGY; MICROBIOLOGY; MISSENSE MUTATION; PATHOGENICITY; PHYSIOLOGY; VIRULENCE;

ADULT; AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; CELL LINE; CELLS, CULTURED; FRANCISELLA TULARENSIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; HUMANS; MACROPHAGES; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; NEUTROPHILS; OPERON; PHAGOSOMES; VIRULENCE; VIRULENCE FACTORS; YOUNG ADULT;

EID: 66549085340     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00229-09     Document Type: Article

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