메뉴 건너뛰기




Volumn 42, Issue 5, 2009, Pages 265-270

Inhibitory effects of flavonoids on TNF-α-induced IL-8 gene expression in HEK 293 cells

Author keywords

Flavonoids; IL 8; Kaempferol; NF B; ROS

Indexed keywords


EID: 66549084491     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/BMBRep.2009.42.5.265     Document Type: Article
Times cited : (75)

References (26)
  • 1
    • 4944228697 scopus 로고    scopus 로고
    • Flavonoids inhibit tumor necrosis factor-alpha-induced up-regulation of intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells through activator protein-1 and nuclear factor-kappaB: structure-activity relationships
    • Chen, C. C., Chow, M. P., Huang, W. C., Lin, Y. C. and Chang, Y. J. (2004) Flavonoids inhibit tumor necrosis factor-alpha-induced up-regulation of intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells through activator protein-1 and nuclear factor-kappaB: structure-activity relationships. Mol. Pharmacol. 66, 683-693.
    • (2004) Mol. Pharmacol. , vol.66 , pp. 683-693
    • Chen, C.C.1    Chow, M.P.2    Huang, W.C.3    Lin, Y.C.4    Chang, Y.J.5
  • 2
    • 33846026738 scopus 로고    scopus 로고
    • Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells
    • Lotito, S. B. and Frei, B. (2006) Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. J. Biol. Chem. 281, 37102-37110.
    • (2006) J. Biol. Chem. , vol.281 , pp. 37102-37110
    • Lotito, S.B.1    Frei, B.2
  • 3
    • 33748580218 scopus 로고    scopus 로고
    • Inhibition of pro-inflammatory markers in primary bone marrow-derived mouse macrophages by naturally occurring flavonoids: analysis of the structure-activity relationship
    • Comalada, M., Ballester, I., Bailón, E., Sierra, S., Xaus, J., Gálvez, J., de Medina, F. S. and Zarzuelo, A. (2006) Inhibition of pro-inflammatory markers in primary bone marrow-derived mouse macrophages by naturally occurring flavonoids: analysis of the structure-activity relationship. Biochem. Pharmacol. 72, 1010-1021.
    • (2006) Biochem. Pharmacol. , vol.72 , pp. 1010-1021
    • Comalada, M.1    Ballester, I.2    Bailón, E.3    Sierra, S.4    Xaus, J.5    Gálvez, J.6    de Medina, F.S.7    Zarzuelo, A.8
  • 4
    • 14844326257 scopus 로고    scopus 로고
    • Inhibitory effects of flavonol glycosides from Cinnamomum osmophloeum on inflammatory mediators in LPS/IFN-gamma-activated murine macrophages
    • Fang, S. H., Rao, Y. K. and Tzeng, Y. M. (2005) Inhibitory effects of flavonol glycosides from Cinnamomum osmophloeum on inflammatory mediators in LPS/IFN-gamma-activated murine macrophages. Bioorg. Med. Chem. 13, 2381-2388.
    • (2005) Bioorg. Med. Chem. , vol.13 , pp. 2381-2388
    • Fang, S.H.1    Rao, Y.K.2    Tzeng, Y.M.3
  • 5
    • 23744474477 scopus 로고    scopus 로고
    • Flavonols inhibit proinflammatory mediator release, intracellular calcium ion levels and protein kinase C theta phosphorylation in human mast cells
    • Kempuraj, D., Madhappan, B., Christodoulou, S., Boucher, W., Cao, J., Papadopoulou, N., Cetrulo, CL. and Theoharides, T. C. (2005) Flavonols inhibit proinflammatory mediator release, intracellular calcium ion levels and protein kinase C theta phosphorylation in human mast cells. Br. J. Pharmacol. 145, 934-944.
    • (2005) Br. J. Pharmacol. , vol.145 , pp. 934-944
    • Kempuraj, D.1    Madhappan, B.2    Christodoulou, S.3    Boucher, W.4    Cao, J.5    Papadopoulou, N.6    Cetrulo, C.L.7    Theoharides, T.C.8
  • 6
    • 32144442544 scopus 로고    scopus 로고
    • Differential activity of kaempferol and quercetin in attenuating tumor necrosis factor receptor family signaling in bone cells
    • Pang, J. L., Ricupero, D. A., Huang, S., Fatma, N., Singh, D. P., Romero, J. R. and Chattopadhyay, N. (2006) Differential activity of kaempferol and quercetin in attenuating tumor necrosis factor receptor family signaling in bone cells. Biochem. Pharmacol. 71, 818-826.
    • (2006) Biochem. Pharmacol. , vol.71 , pp. 818-826
    • Pang, J.L.1    Ricupero, D.A.2    Huang, S.3    Fatma, N.4    Singh, D.P.5    Romero, J.R.6    Chattopadhyay, N.7
  • 7
    • 37549016731 scopus 로고    scopus 로고
    • Commentary: bioavailability of flavonoids and polyphenols: call to arms
    • Hu, M. (2007) Commentary: bioavailability of flavonoids and polyphenols: call to arms. Mol. Pharm. 4, 803-806.
    • (2007) Mol. Pharm. , vol.4 , pp. 803-806
    • Hu, M.1
  • 8
    • 24744448676 scopus 로고    scopus 로고
    • Modulation of apoptosis in HaCaT keratinocytes via differential regulation of ERK signaling pathway by flavonoids
    • Lee, E. R., Kang, Y. J., Kim, J. H., Lee, H. T. and Cho, S. G. (2005) Modulation of apoptosis in HaCaT keratinocytes via differential regulation of ERK signaling pathway by flavonoids. J. Biol. Chem. 280, 31498-31507.
    • (2005) J. Biol. Chem. , vol.280 , pp. 31498-31507
    • Lee, E.R.1    Kang, Y.J.2    Kim, J.H.3    Lee, H.T.4    Cho, S.G.5
  • 9
    • 0141888287 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced nitric oxide production by flavonoids in RAW264. 7 macrophages involves heme oxygenase-1
    • Lin, H. Y., Juan, S. H., Shen, S. C., Hsu, F. L. and Chen, Y. C. (2003) Inhibition of lipopolysaccharide-induced nitric oxide production by flavonoids in RAW264.7 macrophages involves heme oxygenase-1. Biochem. Pharmacol. 66, 1821-1832.
    • (2003) Biochem. Pharmacol. , vol.66 , pp. 1821-1832
    • Lin, H.Y.1    Juan, S.H.2    Shen, S.C.3    Hsu, F.L.4    Chen, Y.C.5
  • 10
    • 38549102077 scopus 로고    scopus 로고
    • TNF-mediated inflammatory disease
    • Bradley, J. R. (2008) TNF-mediated inflammatory disease. J. Pathol. 214, 149-160.
    • (2008) J. Pathol. , vol.214 , pp. 149-160
    • Bradley, J.R.1
  • 11
    • 33645788091 scopus 로고    scopus 로고
    • Modulation of Tumor Necrosis Factor by Microbial Pathogens
    • Rahman, M. M. and McFadden, G. (2006) Modulation of Tumor Necrosis Factor by Microbial Pathogens. PLoS Pathog. 2, 66-77.
    • (2006) PLoS Pathog , vol.2 , pp. 66-77
    • Rahman, M.M.1    McFadden, G.2
  • 12
    • 44349089740 scopus 로고    scopus 로고
    • TNF-α-induced up-regulation of intercellular adhesion molecule-1 is regulated by a Rac-ROS-dependent cascade in human airway epithelial cells
    • Kim, H. J., Hwang, J. S., Woo, C. H., Kim, E. Y., Kim, T. H., Cho, K. J., Seo, J. M., Lee, S. S. and Kim, J.H. (2008) TNF-α-induced up-regulation of intercellular adhesion molecule-1 is regulated by a Rac-ROS-dependent cascade in human airway epithelial cells. Exp. Mol. Med. 40, 167-175.
    • (2008) Exp. Mol. Med. , vol.40 , pp. 167-175
    • Kim, H.J.1    Hwang, J.S.2    Woo, C.H.3    Kim, E.Y.4    Kim, T.H.5    Cho, K.J.6    Seo, J.M.7    Lee, S.S.8    Kim, J.H.9
  • 13
    • 5644222552 scopus 로고    scopus 로고
    • Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction
    • Muppidi, J. R., Tschopp, J. and Siegel, R. M. (2004) Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction. Immunity 4, 461-465.
    • (2004) Immunity , vol.4 , pp. 461-465
    • Muppidi, J.R.1    Tschopp, J.2    Siegel, R.M.3
  • 15
    • 1842850599 scopus 로고    scopus 로고
    • Tumor necrosis factor family ligand-receptor binding
    • Zhang, G. (2004) Tumor necrosis factor family ligand-receptor binding. Curr. Opin. Struct. Biol. 2, 154-160.
    • (2004) Curr. Opin. Struct. Biol. , vol.2 , pp. 154-160
    • Zhang, G.1
  • 16
    • 25844459154 scopus 로고    scopus 로고
    • NF-κB: linking inflammation and immunity to cancer development and progression
    • Karin, M. and Greten, F. R. (2005) NF-κB: linking inflammation and immunity to cancer development and progression. Nat. Rev. Immunol. 10, 749-759.
    • (2005) Nat. Rev. Immunol. , vol.10 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 17
    • 33646536345 scopus 로고    scopus 로고
    • Enzymatic preparation of kaempferol from green tea seed and its antioxidant activity
    • Park, J. S., Rho, H. S., Kim, D. H. and Chang, I. S. (2006) Enzymatic preparation of kaempferol from green tea seed and its antioxidant activity. J. Agric. Food Chem. 54, 2951-2956.
    • (2006) J. Agric. Food Chem. , vol.54 , pp. 2951-2956
    • Park, J.S.1    Rho, H.S.2    Kim, D.H.3    Chang, I.S.4
  • 18
    • 2942596005 scopus 로고    scopus 로고
    • Kaempferol blocks oxidative stress in cerebellar granule cells and reveals a key role for reactive oxygen species production at the plasma membrane in the commitment to apoptosis
    • Samhan-Arias, A. K., Martín-Romero, F. J. and Gutiérrez-Merino, C. (2004) Kaempferol blocks oxidative stress in cerebellar granule cells and reveals a key role for reactive oxygen species production at the plasma membrane in the commitment to apoptosis. Free Radic. Biol. Med. 37, 48-61.
    • (2004) Free Radic. Biol. Med. , vol.37 , pp. 48-61
    • Samhan-Arias, A.K.1    Martín-Romero, F.J.2    Gutiérrez-Merino, C.3
  • 20
    • 23144449789 scopus 로고    scopus 로고
    • Ubiquitin signalling in the NF-κB pathway
    • Chen, Z. J. (2005) Ubiquitin signalling in the NF-κB pathway. Nat. Cell Biol. 7, 758-765.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 758-765
    • Chen, Z.J.1
  • 21
    • 4444359123 scopus 로고    scopus 로고
    • Cellular signalling mechanisms in alcohol-induced liver damage
    • Hoek, J. B. and Pastorino, J. G. (2004) Cellular signalling mechanisms in alcohol-induced liver damage. Semin. Liver Dis. 24, 257-272.
    • (2004) Semin. Liver Dis. , vol.24 , pp. 257-272
    • Hoek, J.B.1    Pastorino, J.G.2
  • 23
    • 0041495303 scopus 로고    scopus 로고
    • NF-κB and c-Jun-dependent regulation of macrophage inflammatory protein-2 gene expression in response to lipopolysaccharide in RAW 264.7 cells
    • Kim, D. S., Han, J. H. and Kwon, H. J. (2003) NF-κB and c-Jun-dependent regulation of macrophage inflammatory protein-2 gene expression in response to lipopolysaccharide in RAW 264.7 cells. Mol. Immunol. 40, 633-643.
    • (2003) Mol. Immunol. , vol.40 , pp. 633-643
    • Kim, D.S.1    Han, J.H.2    Kwon, H.J.3
  • 24
    • 33845390434 scopus 로고    scopus 로고
    • Identification of immunostimulatory oligodeoxynucleotide from Escherichia coli genomic DNA
    • Choi, Y. J., Lee, K. W., Kwon, H. J. and Kim, D. S. (2006) Identification of immunostimulatory oligodeoxynucleotide from Escherichia coli genomic DNA. J. Biochem. Mol. Biol. 39, 788-793.
    • (2006) J. Biochem. Mol. Biol. , vol.39 , pp. 788-793
    • Choi, Y.J.1    Lee, K.W.2    Kwon, H.J.3    Kim, D.S.4
  • 25
    • 13244265694 scopus 로고    scopus 로고
    • Sp1-associated activation of macrophage inflammatory protein-2 promoter by CpG-oligodeoxynucleotide and lipopolysaccharide
    • Lee, K. W., Lee, Y., Kwon, H. J. and Kim, D. S. (2005) Sp1-associated activation of macrophage inflammatory protein-2 promoter by CpG-oligodeoxynucleotide and lipopolysaccharide. Cell Mol. Life Sci. 62, 188-198.
    • (2005) Cell Mol. Life Sci. , vol.62 , pp. 188-198
    • Lee, K.W.1    Lee, Y.2    Kwon, H.J.3    Kim, D.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.