Efficient solid-phase synthesis of oligodeoxynucleotides having a 5′-terminal 2,2,7-trimethylguanosine pyrophosphate linkage

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 13, 2009, Pages 4819-4824

  Ohkubo, Akihiro ^a   Sasaki, Kenji ^a   Noma, Yasuhiro ^a   Tsunoda, Hirosuke ^a   Seio, Kohji ^a   Sekine, Mitsuo ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

2,2,7 Trimethylguanosine cap; Nuclear transport; Silyl linker; Solid phase synthesis; TMG capped DNA

Indexed keywords

2',3' O BIS(TERT BUTYLDIMETHYLSILYL) 2,2,7 N TRIMETHYLGUANOSINE 5' O PHOSPHOROIMIDAZOLIDATE; 2,2,7 TRIMETHYLGUANOSINE PYROPHOSPHATE; GUANOSINE PHOSPHATE; IMIDAZOLE DERIVATIVE; OLIGONUCLEOTIDE; SMALL NUCLEAR RNA; UNCLASSIFIED DRUG;

ARTICLE; GENE THERAPY; NUCLEOTIDE METABOLISM; SOLID PHASE SYNTHESIS;

BASE SEQUENCE; DNA; GENE TRANSFER TECHNIQUES; GUANOSINE; MOLECULAR STRUCTURE; OLIGODEOXYRIBONUCLEOTIDES;

EID: 66449127907     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.04.073     Document Type: Article

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