O-selectivity and utility of phosphorylation mediated by phosphite triester intermediates in the N-unprotected phosphoramidite method

Journal of the American Chemical Society

Volumn 126, Issue 35, 2004, Pages 10884-10896

  Ohkubo, Akihiro ^a,c   Ezawa, Yusuke ^a   Seio, Kohji ^b,c   Sekine, Mitsuo ^a,c  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b Frontier Collab Research Center   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO GROUPS; PHOSPHORYLATION; POLYMER SUPPORTS;

AMINO ACIDS; DNA; MOLECULAR STRUCTURE; PHOSPHORUS; POLYMERS; SYNTHESIS (CHEMICAL);

ESTERS;

1 HYDROXYBENZOTRIAZOLE; 4 N ACETYLDEOXYCYTIDINE; 6 TRIFLUOROMETHYL 1 HYDROXYBENZOTRIAZOLE; BENZIMIDAZOLE DERIVATIVE; BENZIMIDAZOLIUM TRIFLATE; BENZOTRIAZOLE DERIVATIVE; DEOXYCYTIDINE; DNA; ESTER DERIVATIVE; HYDROXYL GROUP; NUCLEOSIDE; OLIGODEOXYNUCLEOTIDE; OLIGOPEPTIDE; PHOSPHITE; PHOSPHORAMIDIC ACID DERIVATIVE; PHOSPHORUS; POLYMER; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMOSENSITIVITY; DNA SYNTHESIS; PHOSPHORYLATION; SOLID; SYNTHESIS;

DEOXYADENOSINES; DEOXYCYTIDINE; DNA; MODELS, MOLECULAR; OLIGODEOXYRIBONUCLEOTIDES; OLIGONUCLEOTIDES; ORGANOPHOSPHORUS COMPOUNDS; PHOSPHITES; PHOSPHORYLATION; THERMODYNAMICS;

EID: 4444352357     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja048125h     Document Type: Article

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