An N-glycosylation site on the β-propeller domain of the integrin α5 subunit plays key roles in both its function and site-specific modification by β1,4-N-acetylglucosaminyltransferase III

Journal of Biological Chemistry

Volumn 284, Issue 18, 2009, Pages 11873-11881

  Sato, Yuya ^a   Isaji, Tomoya ^a   Tajiri, Michiko ^b   Yoshida Yamamoto, Shumi ^b,d   Yoshinaka, Tsuyoshi ^c   Somehara, Toshiaki ^c   Fukuda, Tomohiko ^a   Wada, Yoshinao ^b   Gu, Jianguo ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

^b RESEARCH INSTITUTE FOR MATERNAL AND CHILD HEALTH   (Japan)

^c FUJIFILM Wako Pure Chemical Corporation   (Japan)

^d MUKOGAWA WOMEN'S UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL FUNCTIONS; BLOT ANALYSIS; CELL MIGRATION; FUNCTIONAL REGULATION; GLYCOSYL TRANSFERASE; HETERODIMERIZATION; INTEGRIN; MUTANT CELLS; N-GLYCANS; N-GLYCOSYLATION; N-GLYCOSYLATION SITES; OVER-EXPRESSION; SINGLE MUTANT; SITE-SPECIFIC MODIFICATIONS; WILD TYPES;

CELL ADHESION; ESTERIFICATION; GLYCOSYLATION;

ADHESION;

AGGLUTININ; ALPHA5 INTEGRIN; BETA 1,4 N ACETYLGLUCOSAMINYLTRANSFERASE III; BETA PROPELLER PROTEIN; FIBRONECTIN; LECTIN; MUTANT PROTEIN; N ACETYLGLUCOSAMINE; N ACETYLGLUCOSAMINYLTRANSFERASE; PHYTOHEMAGGLUTININ; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; ALPHA 1,6 MANNOSYLGLYCOPROTEIN BETA 1,6 N ACETYLGLUCOSAMINYLTRANSFERASE; ALPHA-1,6-MANNOSYLGLYCOPROTEIN BETA 1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE; BETA 1,4 MANNOSYL GLYCOPROTEIN BETA 1,4 N ACETYLGLUCOSAMINYLTRANSFERASE; BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE; VERY LATE ACTIVATION ANTIGEN 5;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL ADHESION; CELL MIGRATION; CELL SPREADING; CONTROLLED STUDY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN MODIFICATION; REGULATORY MECHANISM; WILD TYPE; ANIMAL; CELL MOTION; CHO CELL; CRICETULUS; DIMERIZATION; GENETICS; GLYCOSYLATION; HAMSTER; HELA CELL; METABOLISM; MUTATION; PHYSIOLOGY;

ANIMALS; CELL ADHESION; CELL MOVEMENT; CHO CELLS; CRICETINAE; CRICETULUS; DIMERIZATION; FIBRONECTINS; GLYCOSYLATION; HELA CELLS; HUMANS; INTEGRIN ALPHA5; INTEGRIN ALPHA5BETA1; MUTATION; N-ACETYLGLUCOSAMINYLTRANSFERASES;

EID: 66449112293     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807660200     Document Type: Article

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