Composite microspheres induce the sustained release and the control of the initial release of water soluble drugs

Pharmazie

Volumn 64, Issue 4, 2009, Pages 284-286

  Chen, G ^a   He, C X ^b   Xu, D H ^a   Liu, L ^a   Zhang, F J ^a   Xu, J Y ^a   Zheng, C H ^a   Gao, J Q ^b   Yan, M ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Second Affiliated Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CEFAZOLIN; MICROSPHERE; POLYGLACTIN; ALGINIC ACID; CHITOSAN; DRUG; EXCIPIENT; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; WATER;

ANTIBIOTIC THERAPY; ARTICLE; CANCER PAIN; CATHETER INFECTION; CHRONIC PAIN; EPIDURAL ANESTHESIA; SUSTAINED DRUG RELEASE; CHEMISTRY; DELAYED RELEASE FORMULATION; MICROCAPSULE; PARTICLE SIZE; SCANNING ELECTRON MICROSCOPY; SOLUBILITY;

ALGINATES; CAPSULES; CEFAZOLIN; CHITOSAN; DELAYED-ACTION PREPARATIONS; EXCIPIENTS; LACTIC ACID; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; PARTICLE SIZE; PHARMACEUTICAL PREPARATIONS; POLYGLYCOLIC ACID; SOLUBILITY; WATER;

EID: 66449097464     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2009.8333     Document Type: Article

References (9)

1. Crotts G, Sah H, Park T et al. (1997) Adsorption determines in-vitro protein release rate from biodegradable microspheres: quantitative analysis of surface area during degradation. J Control Release 47: 101-111.
2. de Jong PC, Kansen PJ (1994) A comparison of epidural catheters with or without subcutaneous injection ports for treatment of cancer pain. Anesth Analg 78: 94-100.
3. Giteau A, Venier-Julienne MC, Aubert-Pouessel A, Benoit JP (2008) How to achieve sustained and complete protein release from PLGA-based microparticles? Int J Pharm 350: 14-26.
4. Klessig HT, Shows SA, Sekorski A (2003) The use of intradiscal antibiotics for discography: an in vitro study of gentamicin, cefazolin, and clindamycin. Spine 28: 1735-1738.
5. Rathmell JP, Lake T, Ramundo MB (2006) Infectious risks of chronic pain treatments: injection therapy, surgical implants, and intradiscal techniques. Reg Anesth Pain Med 31: 346-352.
6. Shirui Mao, Jing Xu, Cuifang Cai et al. (2004) Effect of WOW process parameters on morphology and burst release of FITC-dextran loaded PLGA microspheres. Int J Pharm 334: 137-148.
7. Smitt PS, Tsafka A, Teng-van de Zande F, van der Holt R, Elswijk-de Vries I, Elfrink E, van den Bent MJ, Vecht CJ (1998) Outcome and complications of epidural analgesia in patients with chronic cancer pain. Cancer 83: 2015-2022.
8. Xu QG, Czernuszka JT (2008) Controlled release of amoxicillin from hydroxyapatite-coated poly(lactic-co-glycolic acid) microspheres. J Control Release 127: 146-153.
9. Zheng CH, Gao JQ, Zhang YP et al. (2004) A protein delivery system: biodegradable alginate-chitosan-poly(lactic-co-glycolic acid) composite microspheres. Biochem Biophys Res Commun 323: 1321-1327.