메뉴 건너뛰기




Volumn 12, Issue 3, 2009, Pages 114-122

Copper deficiency alters the neurochemical profile of developing rat brain

Author keywords

Cerebellum; Copper deficient; Hippocampus; Metabolites; NMR; Rat

Indexed keywords

4 AMINOBUTYRIC ACID; ALANINE; ASCORBIC ACID; ASPARTIC ACID; COPPER; CREATININE; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; GLUTATHIONE; INOSITOL; LACTIC ACID; N ACETYLASPARTIC ACID; N ACETYLASPARTYLGLUTAMIC ACID; PHOSPHATIDYLCHOLINE; PHOSPHOETHANOLAMINE; PHOSPHORYLCHOLINE; TAURINE; CITRIC ACID; CREATINE; CREATINE PHOSPHATE; DRUG DERIVATIVE; N-ACETYLASPARTATE;

EID: 66349111160     PISSN: 1028415X     EISSN: 14768305     Source Type: Journal    
DOI: 10.1179/147683009X423265     Document Type: Article
Times cited : (28)

References (43)
  • 1
    • 33847369883 scopus 로고    scopus 로고
    • Bowman BA and Russell RM. (eds). Washington, DC: International Life Sciences Institute
    • Prohaska JR. Copper. In: Bowman BA and Russell RM. (eds) Present Knowledge in Nutrition. Washington, DC: International Life Sciences Institute, 2006; 458-470.
    • (2006) Present Knowledge in Nutrition , pp. 458-470
    • Prohaska, J.R.1    Copper2
  • 3
    • 78651124591 scopus 로고
    • A sex-linked recessive disorder with retardation of growth, peculiar hair, and focal cerebral and cerebellar degeneration
    • Menkes JH, Alter M, Steigleder GK et al. A sex-linked recessive disorder with retardation of growth, peculiar hair, and focal cerebral and cerebellar degeneration. Pediatrics 1962; 29: 764-779.
    • (1962) Pediatrics , vol.29 , pp. 764-779
    • Menkes, J.H.1    Alter, M.2    Steigleder, G.K.3
  • 4
    • 0031971144 scopus 로고    scopus 로고
    • Menkes syndrome and animal models
    • Mercer JF. Menkes syndrome and animal models. Am J Clin Nutr 1998; 67: 1022S-1028S.
    • (1998) Am J Clin Nutr , vol.67
    • Mercer, J.F.1
  • 5
    • 34548279406 scopus 로고    scopus 로고
    • Differences in ATP7A gene expression underlie intrafamilial variability in Menkes disease/occipital horn syndrome
    • Donsante A, Tang J, Godwin SC et al. Differences in ATP7A gene expression underlie intrafamilial variability in Menkes disease/occipital horn syndrome. J Med Genet 2007; 44: 492-497.
    • (2007) J Med Genet , vol.44 , pp. 492-497
    • Donsante, A.1    Tang, J.2    Godwin, S.C.3
  • 6
    • 0016330759 scopus 로고
    • Primary defect in copper transport underlies mottled mutants in the mouse
    • Hunt DM. Primary defect in copper transport underlies mottled mutants in the mouse. Nature 1974; 249: 852-854.
    • (1974) Nature , vol.249 , pp. 852-854
    • Hunt, D.M.1
  • 7
    • 0016146549 scopus 로고
    • Copper deficiency in the developing rat brain: A possible model for Menkes' steely-hair disease
    • Prohaska JR, Wells WW. Copper deficiency in the developing rat brain: a possible model for Menkes' steely-hair disease. J Neurochem 1974; 23: 91-98.
    • (1974) J Neurochem , vol.23 , pp. 91-98
    • Prohaska, J.R.1    Wells, W.W.2
  • 8
    • 0014184068 scopus 로고
    • Copper deficiency in the guinea pig
    • Everson GJ, Tsai HC,Wang TI. Copper deficiency in the guinea pig. J Nutr 1967; 93: 533-540.
    • (1967) J Nutr , vol.93 , pp. 533-540
    • Everson, G.J.1    Tsai, H.C.2    Wang, T.I.3
  • 9
    • 33847279384 scopus 로고    scopus 로고
    • ATP7A (Menkes protein) functions in axonal targeting and synaptogenesis
    • El Meskini R, Crabtree KL, Cline LB et al. ATP7A (Menkes protein) functions in axonal targeting and synaptogenesis. Mol Cell Neurosci 2007; 34: 409-421.
    • (2007) Mol Cell Neurosci , vol.34 , pp. 409-421
    • El Meskini, R.1    Crabtree, K.L.2    Cline, L.B.3
  • 10
    • 0242400141 scopus 로고
    • Changes in brain enzymes accompanying deficiencies of the trace elements, copper, selenium, or zinc
    • McHowell J, Gawthorne JM, White CL. (eds). Canberra: Australian Academy of Science
    • Prohaska JR. Changes in brain enzymes accompanying deficiencies of the trace elements, copper, selenium, or zinc. In: McHowell J, Gawthorne JM, White CL. (eds) Trace Element Metabolism in Man and Animals (TEMA-4). Canberra: Australian Academy of Science, 1981; 275-282.
    • (1981) Trace Element Metabolism in Man and Animals (TEMA-4) , pp. 275-282
    • Prohaska, J.R.1
  • 12
    • 3543134811 scopus 로고    scopus 로고
    • Abnormal motor function persists following recovery from perinatal copper deficiency in rats
    • Penland JG, Prohaska JR. Abnormal motor function persists following recovery from perinatal copper deficiency in rats. J Nutr 2004; 134: 1984-1988.
    • (2004) J Nutr , vol.134 , pp. 1984-1988
    • Penland, J.G.1    Prohaska, J.R.2
  • 13
    • 0028874691 scopus 로고
    • Moderate copper deprivation during gestation and lactation affects dentate gyrus and hippocampal maturation in immature male rats
    • Hunt CD, Idso JP. Moderate copper deprivation during gestation and lactation affects dentate gyrus and hippocampal maturation in immature male rats. J Nutr 1995; 125: 2700-2710.
    • (1995) J Nutr , vol.125 , pp. 2700-2710
    • Hunt, C.D.1    Idso, J.P.2
  • 14
    • 0006137285 scopus 로고
    • The relation of iron and copper tocytochrome and oxidase content of animal tissues
    • Cohen E, Elvehjem CA. The relation of iron and copper tocytochrome and oxidase content of animal tissues. J Biol Chem 1934; 107: 97-105.
    • (1934) J Biol Chem , vol.107 , pp. 97-105
    • Cohen, E.1    Elvehjem, C.A.2
  • 15
    • 41549119144 scopus 로고    scopus 로고
    • Variable response of selected cuproproteins in rat choroid plexus and cerebellum following perinatal copper deficiency
    • Gybina AA, Prohaska JR. Variable response of selected cuproproteins in rat choroid plexus and cerebellum following perinatal copper deficiency. Genes Nutr 2006; 1: 51-60.
    • (2006) Genes Nutr , vol.1 , pp. 51-60
    • Gybina, A.A.1    Prohaska, J.R.2
  • 16
    • 0016759836 scopus 로고
    • Copper deficiency in the developing rat brain: Evidence for abnormal mitochondria
    • Prohaska JR, Wells WW. Copper deficiency in the developing rat brain: evidence for abnormal mitochondria. J Neurochem 1975; 25: 221-228.
    • (1975) J Neurochem , vol.25 , pp. 221-228
    • Prohaska, J.R.1    Wells, W.W.2
  • 17
    • 0032783060 scopus 로고    scopus 로고
    • Clinical manifestations and treatment of Menkes disease and its variants
    • Kodama H, Murata Y, Kobayashi M. Clinical manifestations and treatment of Menkes disease and its variants. Pediatr Int 1999; 41: 423-429.
    • (1999) Pediatr Int , vol.41 , pp. 423-429
    • Kodama, H.1    Murata, Y.2    Kobayashi, M.3
  • 18
    • 0019472287 scopus 로고
    • Metabolic consequences of trichopoliodystrophy
    • Loyola MA, Dodson WE. Metabolic consequences of trichopoliodystrophy. J Pediatr 1981; 98: 588-591.
    • (1981) J Pediatr , vol.98 , pp. 588-591
    • Loyola, M.A.1    Dodson, W.E.2
  • 19
    • 20944448886 scopus 로고    scopus 로고
    • The effects of copperhistidine therapy on brain metabolism in a patient with Menkes disease: A proton magnetic resonance spectroscopic study
    • Munakata M, Sakamoto O, Kitamura T et al. The effects of copperhistidine therapy on brain metabolism in a patient with Menkes disease: a proton magnetic resonance spectroscopic study. Brain Dev 2005; 27: 297-300.
    • (2005) Brain Dev , vol.27 , pp. 297-300
    • Munakata, M.1    Sakamoto, O.2    Kitamura, T.3
  • 20
    • 41549127926 scopus 로고    scopus 로고
    • Copper deficiency results in AMPactivated protein kinase activation and acetylCoA carboxylase phosphorylation in rat cerebellum
    • Gybina AA, Prohaska JR. Copper deficiency results in AMPactivated protein kinase activation and acetylCoA carboxylase phosphorylation in rat cerebellum. Brain Res 2008; 1204: 69-76.
    • (2008) Brain Res , vol.1204 , pp. 69-76
    • Gybina, A.A.1    Prohaska, J.R.2
  • 21
    • 0029767436 scopus 로고    scopus 로고
    • Inhibition of Nacetylaspartate production: Implications for 1H MRS studies in vivo
    • Bates TE, Strangward M, Keelan J et al. Inhibition of Nacetylaspartate production: implications for 1H MRS studies in vivo. Neuroreport 1996; 7: 1397-1400.
    • (1996) Neuroreport , vol.7 , pp. 1397-1400
    • Bates, T.E.1    Strangward, M.2    Keelan, J.3
  • 22
    • 0031731910 scopus 로고    scopus 로고
    • N-Acetyl aspartate: A marker for neuronal loss or mitochondrial dysfunction
    • Clark JB. N-Acetyl aspartate: a marker for neuronal loss or mitochondrial dysfunction. Dev Neurosci 1998; 20: 271-276.
    • (1998) Dev Neurosci , vol.20 , pp. 271-276
    • Clark, J.B.1
  • 23
    • 33847141978 scopus 로고    scopus 로고
    • N-Acetylaspartate in the CNS: From neurodiagnostics to neurobiology
    • Moffett JR, Ross B, Arun P et al. N-Acetylaspartate in the CNS: from neurodiagnostics to neurobiology. Prog Neurobiol 2007; 81: 89-131.
    • (2007) Prog Neurobiol , vol.81 , pp. 89-131
    • Moffett, J.R.1    Ross, B.2    Arun, P.3
  • 24
    • 38149135603 scopus 로고    scopus 로고
    • Assessment of mitochondrial impairment in traumatic brain injury using highresolution proton magnetic resonance spectroscopy
    • Signoretti S, Marmarou A, Aygok GA et al. Assessment of mitochondrial impairment in traumatic brain injury using highresolution proton magnetic resonance spectroscopy. J Neurosurg 2008; 108: 42-52.
    • (2008) J Neurosurg , vol.108 , pp. 42-52
    • Signoretti, S.1    Marmarou, A.2    Aygok, G.A.3
  • 25
    • 18144405022 scopus 로고    scopus 로고
    • Rat brain iron concentration is lower following perinatal copper deficiency
    • Prohaska JR, Gybina AA. Rat brain iron concentration is lower following perinatal copper deficiency. J Neurochem 2005; 93: 698-705.
    • (2005) J Neurochem , vol.93 , pp. 698-705
    • Prohaska, J.R.1    Gybina, A.A.2
  • 26
    • 0141639898 scopus 로고    scopus 로고
    • Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus
    • Rao R, Tkac I, Townsend EL et al. Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus. J Nutr 2003; 133: 3215-3221. (Pubitemid 37222244)
    • (2003) Journal of Nutrition , vol.133 , Issue.10 , pp. 3215-3221
    • Rao, R.1    Tkac, I.2    Townsend, E.L.3    Gruetter, R.4    Georgieff, M.K.5
  • 27
    • 34247102590 scopus 로고    scopus 로고
    • Gestational and lactational iron deficiency alters the developing striatal metabolome and associated behaviors in young rats
    • Ward KL, Tkac I, Jing Y et al. Gestational and lactational iron deficiency alters the developing striatal metabolome and associated behaviors in young rats. J Nutr 2007; 137: 1043-1049.
    • (2007) J Nutr , vol.137 , pp. 1043-1049
    • Ward, K.L.1    Tkac, I.2    Jing, Y.3
  • 28
    • 0242410143 scopus 로고    scopus 로고
    • Increased rat brain cytochrome c correlates with degree of perinatal copper deficiency rather than apoptosis
    • Gybina AA, Prohaska JR. Increased rat brain cytochrome c correlates with degree of perinatal copper deficiency rather than apoptosis. J Nutr 2003; 133: 3361-3368.
    • (2003) J Nutr , vol.133 , pp. 3361-3368
    • Gybina, A.A.1    Prohaska, J.R.2
  • 29
    • 0027200329 scopus 로고
    • Automatic, localized in vivo adjustment of all first- and second-order shim coils
    • Gruetter R. Automatic, localized in vivo adjustment of all first- and second-order shim coils. Magn Reson Med 1993; 29: 804-811.
    • (1993) Magn Reson Med , vol.29 , pp. 804-811
    • Gruetter, R.1
  • 30
    • 0342948677 scopus 로고    scopus 로고
    • Field mapping without reference scan using asymmetric echo-planar techniques
    • Gruetter R, Tkac I. Field mapping without reference scan using asymmetric echo-planar techniques. Magn Reson Med 2000; 43: 319-323.
    • (2000) Magn Reson Med , vol.43 , pp. 319-323
    • Gruetter, R.1    Tkac, I.2
  • 31
    • 4243050487 scopus 로고    scopus 로고
    • Highly resolved in vivo 1H NMR spectroscopy of the mouse brain at 9.4 T
    • Tkac I, Henry PG, Andersen P et al. Highly resolved in vivo 1H NMR spectroscopy of the mouse brain at 9.4 T. Magn Reson Med 2004; 52: 478-484.
    • (2004) Magn Reson Med , vol.52 , pp. 478-484
    • Tkac, I.1    Henry, P.G.2    Andersen, P.3
  • 32
    • 0027375098 scopus 로고
    • Estimation of metabolite concentrations from localized in vivo proton NMR spectra
    • Provencher SW. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med 1993; 30: 672-679.
    • (1993) Magn Reson Med , vol.30 , pp. 672-679
    • Provencher, S.W.1
  • 33
    • 0033226834 scopus 로고    scopus 로고
    • Toward an in vivo neurochemical profile: Quantification of 18 metabolites in shortecho-time(1)H NMR spectra of the rat brain
    • Pfeuffer J, Tkac I, Provencher SW et al. Toward an in vivo neurochemical profile: quantification of 18 metabolites in shortecho-time (1)H NMR spectra of the rat brain. J Magn Reson 1999; 141: 104-120.
    • (1999) J Magn Reson , vol.141 , pp. 104-120
    • Pfeuffer, J.1    Tkac, I.2    Provencher, S.W.3
  • 34
    • 0018178434 scopus 로고
    • A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples
    • Markwell MA, Haas SM, Bieber LL et al. A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Anal Biochem 1978; 87: 206-210.
    • (1978) Anal Biochem , vol.87 , pp. 206-210
    • Markwell, M.A.1    Haas, S.M.2    Bieber, L.L.3
  • 36
    • 0020438908 scopus 로고
    • A kinetic study of pyrophosphate: Fructose-6-phosphate phosphotransferase from potato tubers. Application to a microassay of fructose 2,6-bisphosphate
    • Van Schaftingen E, Lederer B, Bartrons R et al. A kinetic study of pyrophosphate: fructose-6-phosphate phosphotransferase from potato tubers. Application to a microassay of fructose 2,6-bisphosphate. Eur J Biochem 1982; 129: 191-195.
    • (1982) Eur J Biochem , vol.129 , pp. 191-195
    • Van Schaftingen, E.1    Lederer, B.2    Bartrons, R.3
  • 37
    • 0021061056 scopus 로고
    • Decreased brain ascorbate levels in copperdeficient mice and in brindled mice
    • Prohaska JR, Cox DA. Decreased brain ascorbate levels in copperdeficient mice and in brindled mice. J Nutr 1983; 113: 2623-2629.
    • (1983) J Nutr , vol.113 , pp. 2623-2629
    • Prohaska, J.R.1    Cox, D.A.2
  • 38
    • 54549108051 scopus 로고    scopus 로고
    • Fructose 2,6 bisphosphate is lower in copper deficient rat cerebellum despite higher content of phosphorylated AMP-activated protein kinase
    • Gybina AA, Prohaska JR. Fructose 2,6 bisphosphate is lower in copper deficient rat cerebellum despite higher content of phosphorylated AMP-activated protein kinase. Exp Biol Med 2008; 233: 1262-1270.
    • (2008) Exp Biol Med , vol.233 , pp. 1262-1270
    • Gybina, A.A.1    Prohaska, J.R.2
  • 39
    • 0021677159 scopus 로고
    • Ascorbic acid synthesis and concentrations in organs of copper-deficient and brindled mice
    • Prohaska JR, Cox DA, Bailey WR. Ascorbic acid synthesis and concentrations in organs of copper-deficient and brindled mice. Biol Trace Elem Res 1984; 6: 441-453.
    • (1984) Biol Trace Elem Res , vol.6 , pp. 441-453
    • Prohaska, J.R.1    Cox, D.A.2    Bailey, W.R.3
  • 40
    • 33847214861 scopus 로고    scopus 로고
    • Isoflurane strongly affects the diffusion of intracellular metabolites, as shown by 1H nuclear magnetic resonance spectroscopy of the monkey brain
    • Valette J, Guillermier M, Besret L et al. Isoflurane strongly affects the diffusion of intracellular metabolites, as shown by 1H nuclear magnetic resonance spectroscopy of the monkey brain. J Cereb Blood Flow Metab 2007; 27: 588-596.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 588-596
    • Valette, J.1    Guillermier, M.2    Besret, L.3
  • 41
    • 0023229939 scopus 로고
    • Comparison of the effects of volatile anesthetics on brain glucose metabolism in rats
    • Kofke WA, Hawkins RA, Davis DW et al. Comparison of the effects of volatile anesthetics on brain glucose metabolism in rats. Anesthesiology 1987; 66: 810-813.
    • (1987) Anesthesiology , vol.66 , pp. 810-813
    • Kofke, W.A.1    Hawkins, R.A.2    Davis, D.W.3
  • 42
    • 0016168247 scopus 로고
    • Copper deficiency and the central nervous system. Myelination in the rat: Morphological and biochemical studies
    • Dipaolo RV, Kanfer JN, Newberne PM. Copper deficiency and the central nervous system. Myelination in the rat: morphological and biochemical studies. J Neuropathol Exp Neurol 1974; 33: 226-236.
    • (1974) J Neuropathol Exp Neurol , vol.33 , pp. 226-236
    • Dipaolo, R.V.1    Kanfer, J.N.2    Newberne, P.M.3
  • 43
    • 54749084673 scopus 로고    scopus 로고
    • Iron injection restores brain iron and hemoglobin deficits in perinatal copper deficient rats
    • Pyatskowit JW, Prohaska JR. Iron injection restores brain iron and hemoglobin deficits in perinatal copper deficient rats. J Nutr 2008; 138: 1880-1886.
    • (2008) J Nutr , vol.138 , pp. 1880-1886
    • Pyatskowit, J.W.1    Prohaska, J.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.