메뉴 건너뛰기




Volumn 50, Issue SUPPL., 2009, Pages

The ins (cell) and outs (plasma) of apolipoprotein A-V

Author keywords

Apolipoprotein A V intracellular trafficking; Apolipoprotein A V lipid binding; Apolipoprotein A V lipid droplet association; Apolipoprotein A V molecular structure; Apolipoprotein A V mutants; Heparan sulfate proteoglycans

Indexed keywords

APOLIPOPROTEIN A; TRIACYLGLYCEROL;

EID: 66349097499     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.R800050-JLR200     Document Type: Review
Times cited : (28)

References (46)
  • 1
    • 0035812707 scopus 로고    scopus 로고
    • An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing
    • DOI 10.1126/science.1064852
    • Pennacchio, L. A., M. Olivier, J. A. Hubacek, J. C. Cohen, D. R. Cox, J-C. Fruchart, R. M. Krauss, and E. M. Rubin. 2001. An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. Science. 294: 169-173. (Pubitemid 32952971)
    • (2001) Science , vol.294 , Issue.5540 , pp. 169-173
    • Pennacchio, L.A.1    Olivier, M.2    Hubacek, J.A.3    Cohen, J.C.4    Cox, D.R.5    Fruchart, J.-C.6    Krauss, R.M.7    Rubin, E.M.8
  • 3
    • 10644240816 scopus 로고    scopus 로고
    • Probing Prometheus: Fat fueling the fire?
    • DOI 10.1002/hep.20522
    • Farrell, G. C. 2004. Probing Prometheus: fat fueling the fire? Hepatology. 40: 1252-1255. (Pubitemid 39656997)
    • (2004) Hepatology , vol.40 , Issue.6 , pp. 1252-1255
    • Farrell, G.C.1
  • 4
    • 10644248333 scopus 로고    scopus 로고
    • Disruption of hepatic adipogenesis is associated with impaired liver regeneration in mice
    • DOI 10.1002/hep.20462
    • Shteyer, E., Y. Liao, L. J. Muglia, P. S. Hruz, and D. A. Rudnick. 2004. Disruption of hepatic adipogenesis is associated with impaired liver regeneration in mice. Hepatology. 40: 1322-1332. (Pubitemid 39657006)
    • (2004) Hepatology , vol.40 , Issue.6 , pp. 1322-1332
    • Shteyer, E.1    Liao, Y.2    Muglia, L.J.3    Hruz, P.W.4    Rudnick, D.A.5
  • 7
    • 0036889986 scopus 로고    scopus 로고
    • The genetic effect of the apoprotein AV gene on the serum triglyceride level in Japanese
    • DOI 10.1016/S0021-9150(02)00252-6, PII S0021915002002526
    • Nabika, T., S. Nasreen, S. Kobayashi, and J. Masuda. 2002. The genetic effect of the apoprotein AV gene on the serum triglyceride level in Japanese. Atherosclerosis. 165: 201-204. (Pubitemid 35333346)
    • (2002) Atherosclerosis , vol.165 , Issue.2 , pp. 201-204
    • Nabika, T.1    Nasreen, S.2    Kobayashi, S.3    Masuda, J.4
  • 9
    • 30844433948 scopus 로고    scopus 로고
    • Apolipoprotein A5: A potential modulator of plasma triglyceride levels in Turks
    • Hodoglugil, U., S. Tanyolac, D.W. Williamson, Y. Huang, and R.W. Mahley. 2005. Apolipoprotein A5: a potential modulator of plasma triglyceride levels in Turks. J. Lipid Res. 47: 144-153.
    • (2005) J. Lipid Res. , vol.47 , pp. 144-153
    • Hodoglugil, U.1    Tanyolac, S.2    Williamson, D.W.3    Huang, Y.4    Mahley, R.W.5
  • 10
    • 23344440871 scopus 로고    scopus 로고
    • Determination of the functionality of common APOA5 polymorphisms
    • DOI 10.1074/jbc.M502144200
    • Talmud, P. J., J. Palmen, W. Putt, L. Lins, and S. E. Humphries. 2005. Determination of the functionality of common APOA5 polymorphisms. J. Biol. Chem. 280: 28215-28220. (Pubitemid 41105717)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.31 , pp. 28215-28220
    • Talmud, P.J.1    Palmen, J.2    Putt, W.3    Lins, L.4    Humphries, S.E.5
  • 11
    • 36448971223 scopus 로고    scopus 로고
    • In vivo characterization of human APOA5 haplotypes
    • DOI 10.1016/j.ygeno.2007.08.003, PII S0888754307002030
    • Ahituv, N., J. Akiyama, A. Chapman-Helleboid, J. Fruchart, and L. A. Pennacchio. 2007. In vivo characterization of human APOA5 haplotypes. Genomics. 90: 674-679. (Pubitemid 350166831)
    • (2007) Genomics , vol.90 , Issue.6 , pp. 674-679
    • Ahituv, N.1    Akiyama, J.2    Chapman-Helleboid, A.3    Fruchart, J.4    Pennacchio, L.A.5
  • 13
    • 12944295219 scopus 로고    scopus 로고
    • The novel apolipoprotein a5 is present in human serum, is associated with VLDL, HDL, and chylomicrons, and circulates at very low concentrations compared with other apolipoproteins
    • DOI 10.1373/clinchem.2004.040824
    • O'Brien, P. J., W. E. Alborn, J. H. Sloan, M. Ulmer, A. Boodhoo, M. D. Knierman, A. E. Schultze, and R. J. Konrad. 2005. The novel apolipoprotein A5 is present in human serum, is associated with VLDL, HDL, and chylomicrons, and circulates at very low concentrations compared with other apolipoproteins. Clin. Chem. 51: 351-359. (Pubitemid 40175805)
    • (2005) Clinical Chemistry , vol.51 , Issue.2 , pp. 351-359
    • O'Brien, P.J.1    Alborn, W.E.2    Sloan, J.H.3    Ulmer, M.4    Boodhoo, A.5    Knierman, M.D.6    Schultze, A.E.7    Konrad, R.J.8
  • 16
    • 33748507076 scopus 로고    scopus 로고
    • The apolipoprotein A-V genotype and plasma apolipoprotein A-V and triglyceride levels: Prospective risk of type 2 diabetes. Results from the Northwick Park Heart Study II
    • DOI 10.1007/s00125-006-0387-0
    • Talmud, P. J., J. A. Cooper, H. Hattori, I. P. Miller, G. J. Miller, and S. E. Humphries. 2006. The apolipoprotein A-V genotype and plasma apolipoprotein A-V and triglyceride levels: prospective risk of type 2 diabetes. Results from the Northwick Park Heart Study II. Diabetologia. 49: 2337-2340. (Pubitemid 44359094)
    • (2006) Diabetologia , vol.49 , Issue.10 , pp. 2337-2340
    • Talmud, P.J.1    Cooper, J.A.2    Hattori, H.3    Miller, I.P.4    Miller, G.J.5    Humphries, S.E.6
  • 19
    • 34548171784 scopus 로고    scopus 로고
    • Effects of apoA-V on HDL and VLDL metabolism in APOC3 transgenic mice
    • DOI 10.1194/jlr.M600498-JLR200
    • Qu, S., G. Perdomo, D. Su, F. M. D'Souza, N. S. Shachter, and H. H. Dong. 2007. Effects of apoA-V on HdL and VLDl metabolism in APOC3 transgenic mice. J. Lipid Res. 48: 1476-1487. (Pubitemid 47312010)
    • (2007) Journal of Lipid Research , vol.48 , Issue.7 , pp. 1476-1487
    • Qu, S.1    Perdomo, G.2    Su, D.3    D'Souza, F.M.4    Shachter, N.S.5    Dong, H.H.6
  • 21
    • 42949117999 scopus 로고    scopus 로고
    • Effect of apolipoprotein A-Von plasma triglyceride, lipoprotein size and composition in genetically engineered mice
    • Nelbach, L., X. Shu, R. J. Konrad, R. O. Ryan, and T. M. Forte. 2008. Effect of apolipoprotein A-Von plasma triglyceride, lipoprotein size and composition in genetically engineered mice. J. Lipid Res. 49: 572-580.
    • (2008) J. Lipid Res. , vol.49 , pp. 572-580
    • Nelbach, L.1    Shu, X.2    Konrad, R.J.3    Ryan, R.O.4    Forte, T.M.5
  • 22
    • 34548154320 scopus 로고    scopus 로고
    • Apolipoprotein A-V association with intracellular lipid droplets
    • DOI 10.1194/jlr.C700002-JLR200
    • Shu, X., J. Chan, R. O. Ryan, and T. M. Forte. 2007. Apolipoprotein A-V association with intracellular lipid droplets. J. Lipid Res. 48: 1445-1450. (Pubitemid 47312006)
    • (2007) Journal of Lipid Research , vol.48 , Issue.7 , pp. 1445-1450
    • Shu, X.1    Chan, J.2    Ryan, R.O.3    Forte, T.M.4
  • 23
    • 33644551545 scopus 로고    scopus 로고
    • Definitive N-terminal protein sequence and further characterization of the novel apolipoprotein A5 in human serum
    • Alborn, W. E., M. G. Johnson, M. J. Prince, and R. J. Konrad. 2006. Definitive N-terminal protein sequence and further characterization of the novel apolipoprotein A5 in human serum. Clin. Chem. 52: 514-517.
    • (2006) Clin. Chem. , vol.52 , pp. 514-517
    • Alborn, W.E.1    Johnson, M.G.2    Prince, M.J.3    Konrad, R.J.4
  • 24
    • 0041570292 scopus 로고    scopus 로고
    • Structure-function studies of human apolipoprotein A-V: A regulator of plasma lipid homeostasis
    • DOI 10.1021/bi034509t
    • Beckstead, J. A., M. N. Oda, D. D. O. Martin, T. M. Forte, J. K. Bielicki, T. Berger, R. Luty, C. M. Kay, and R. O. Ryan. 2003. Structure-function studies of human Apolipoprotein A-V: a regulator of plasma lipid homeostasis. Biochemistry. 42: 9416-9423. (Pubitemid 36959249)
    • (2003) Biochemistry , vol.42 , Issue.31 , pp. 9416-9423
    • Beckstead, J.A.1    Oda, M.N.2    Martin, D.D.O.3    Forte, T.M.4    Bielicki, J.K.5    Berger, T.6    Luty, R.7    Kay, C.M.8    Ryan, R.O.9
  • 26
    • 49749136969 scopus 로고    scopus 로고
    • The N-terminus of apolipoprotein A-V adopts a helix bundle molecular architecture
    • Wong, K., D. Lee, J. A. Beckstead, P. M. M. Weers, C. M. Kay, and R. O. Ryan. 2008. The N-terminus of apolipoprotein A-V adopts a helix bundle molecular architecture. Biochemistry. 33: 8768-8774.
    • (2008) Biochemistry. , vol.33 , pp. 8768-8774
    • Wong, K.1    Lee, D.2    Beckstead, J.A.3    Weers, P.M.M.4    Kay, C.M.5    Ryan, R.O.6
  • 27
    • 21844445574 scopus 로고    scopus 로고
    • Apolipoprotein A-V-heparin interactions: Implications for plasma lipoprotein metabolism
    • DOI 10.1074/jbc.M501589200
    • Lookene, A., J. A. Beckstead, S. Nilsson, G. Olivecrona, and R. O. Ryan. 2005. Apolipoprotein A-V heparin interactions: implications for plasma lipoprotein metabolism. J. Biol. Chem. 280: 25383-25387. (Pubitemid 40962241)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.27 , pp. 25383-25387
    • Lookene, A.1    Beckstead, J.A.2    Nilsson, S.3    Olivecrona, G.4    Ryan, R.O.5
  • 28
    • 20144375048 scopus 로고    scopus 로고
    • Apolipoprotein AV accelerates plasma hydrolysis of triglyceride-rich lipoproteins by interaction with proteoglycan-bound lipoprotein lipase
    • DOI 10.1074/jbc.M411412200
    • Merkel, M., B. Loeffler, M. Kluger, N. Fabig, G. Geppert, L. A. Pennacchio, A. Laatsch, and J. Heeren. 2005. Apolipoprotein AV accelerates plasma hydrolysis of triglyceride-rich lipoproteins by interaction with proteoglycan-bound lipoprotein lipase. J. Biol. Chem. 280: 21553-21560. (Pubitemid 40805722)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.22 , pp. 21553-21560
    • Merkel, M.1    Loeffler, B.2    Kluger, M.3    Fabig, N.4    Geppert, G.5    Pennacchio, L.A.6    Laatsch, A.7    Heeren, J.8
  • 29
    • 33947706206 scopus 로고    scopus 로고
    • Apolipoprotein A-V interaction with members of the low density lipoprotein receptor gene family
    • DOI 10.1021/bi7000533
    • Nilsson, S. K., A. Lookene, J. A. Beckstead, G. Gliemann, R. O. Ryan, and G. Olivecrona. 2007. Apolipoprotein A-V interaction with members of the low density lipoprotein receptor gene family. Biochemistry. 46: 3896-3904. (Pubitemid 46493490)
    • (2007) Biochemistry , vol.46 , Issue.12 , pp. 3896-3904
    • Nilsson, S.K.1    Lookene, A.2    Beckstead, J.A.3    Gliemann, J.4    Ryan, R.O.5    Olivecrona, G.6
  • 30
    • 0141841622 scopus 로고    scopus 로고
    • A novel genetic variant in the apolipoprotein A5 gene is associated with hypertriglyceridemia
    • Kao, J. T., H. C. Wen, K. L. Chien, H. C. Hsu, and S. W. Lin. 2003. A novel genetic variant in the apolipoprotein A5 gene is associated with hypertriglyceridemia. Hum. Mol. Genet. 12: 2533-2539.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 2533-2539
    • Kao, J.T.1    Wen, H.C.2    Chien, K.L.3    Hsu, H.C.4    Lin, S.W.5
  • 31
    • 33644539827 scopus 로고    scopus 로고
    • A genetic variant c.553G > T in the apolipoprotein A5 gene is associated with an increased risk of coronary artery disease and altered triglyceride levels in a Chinese population
    • Tang, Y., P. Sun, D. Guo, A. Ferro, Y. Ji, Q. Chen, and L. Fan. 2006. A genetic variant c.553G > T in the apolipoprotein A5 gene is associated with an increased risk of coronary artery disease and altered triglyceride levels in a Chinese population. Atherosclerosis. 185: 433-437.
    • (2006) Atherosclerosis , vol.185 , pp. 433-437
    • Tang, Y.1    Sun, P.2    Guo, D.3    Ferro, A.4    Ji, Y.5    Chen, Q.6    Fan, L.7
  • 33
    • 33644794350 scopus 로고    scopus 로고
    • Apolipoprotein A-V deficiency results in marked hypertriglyceridemia attributable to decreased lipolysis of triglyceride-rich lipoproteins and removal of their remnants
    • DOI 10.1161/01.ATV.0000186189.26141.12, PII 0004360520051200000021
    • Grosskopf, I., N. Baroukh, S. J. Lee, Y. Kamari, D. Harats, E. M. Rubin, L. A. Pennacchio, and A. D. Cooper. 2005. Apolipoprotein A-V deficiency results in marked hypertriglyceridemia attributable to decreased lipolysis of triglyceride-rich lipoproteins and removal of their remnants. Arterioscler. Thromb. Vasc. Biol. 25: 2573-2579. (Pubitemid 43732281)
    • (2005) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.25 , Issue.12 , pp. 2573-2579
    • Grosskopf, I.1    Baroukh, N.2    Lee, S.-J.3    Kamari, Y.4    Harats, D.5    Rubin, E.M.6    Pennacchio, L.A.7    Cooper, A.D.8
  • 34
    • 34548185752 scopus 로고    scopus 로고
    • Avian apolipoprotein A-V binds to LDL receptor gene family members
    • DOI 10.1194/jlr.C600026-JLR200
    • Dichlberger, A., L. A. Cogburn, J. Nimpf, and W. J. Schneider. 2007. Avian apolipoprotein A-V binds to LDL receptor gene family members. J. Lipid Res. 48: 1451-1456. (Pubitemid 47312007)
    • (2007) Journal of Lipid Research , vol.48 , Issue.7 , pp. 1451-1456
    • Dichlberger, A.1    Cogburn, L.A.2    Nimpf, J.3    Schneider, W.J.4
  • 35
    • 54449087031 scopus 로고    scopus 로고
    • Endocytosis of apolipoprotein AV by members of the low density lipoprotein receptor and the VPS10p domain receptor families
    • Nilsson, S. K., S. Christensen, M. K. Raarup, R. O. Ryan, M. S. Nielsen, and G. Olivecrona. 2008. Endocytosis of apolipoprotein AV by members of the low density lipoprotein receptor and the VPS10p domain receptor families. J. Biol. Chem. 283: 25920-25927.
    • (2008) J. Biol. Chem. , vol.283 , pp. 25920-25927
    • Nilsson, S.K.1    Christensen, S.2    Raarup, M.K.3    Ryan, R.O.4    Nielsen, M.S.5    Olivecrona, G.6
  • 38
    • 3142581525 scopus 로고    scopus 로고
    • ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglycerides (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis
    • DOI 10.1074/jbc.M403240200
    • Schaap, F. G., P. C. Rensen, P. J. Voshol, C. Vrins, H. N. van der Vliet, R. A. Chamuleau, L. M. Havekes, A. K. Groen, and K. W. van Dijk. 2004. ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein- triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis. J. Biol. Chem. 279: 27941-27947. (Pubitemid 38900062)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.27 , pp. 27941-27947
    • Schaap, F.G.1    Rensen, P.C.N.2    Voshol, P.J.3    Vrins, C.4    Van Der, V.H.N.5    Chamuleau, R.A.F.M.6    Havekes, L.M.7    Groen, A.K.8    Van Dijk, K.W.9
  • 40
    • 33646558304 scopus 로고    scopus 로고
    • Apolipoproteins C-III and A-V as predictors of very-low-density lipoprotein triglyceride and apolipoprotein B-100 kinetics
    • Chan, D. C., G. F. Watts, M. N. Nguyen, and P. H. R. Barrett. 2006. Apolipoproteins C-III and A-V as predictors of very-low-density lipoprotein triglyceride and apolipoprotein B-100 kinetics. Arterioscler. Thromb. Vasc. Biol. 26: 590-596.
    • (2006) Arterioscler. Thromb. Vasc. Biol. , vol.26 , pp. 590-596
    • Chan, D.C.1    Watts, G.F.2    Nguyen, M.N.3    Barrett, P.H.R.4
  • 41
    • 51449118230 scopus 로고    scopus 로고
    • Intracellular lipid droplet targeting by apolipoprotein A-V requires the carboxyl-terminal segment
    • Shu, X., R. O. Ryan, and T. M. Forte. 2008. Intracellular lipid droplet targeting by apolipoprotein A-V requires the carboxyl-terminal segment. J. Lipid Res. 49: 1670-1676.
    • (2008) J. Lipid Res. , vol.49 , pp. 1670-1676
    • Shu, X.1    Ryan, R.O.2    Forte, T.M.3
  • 43
    • 3142640798 scopus 로고    scopus 로고
    • Structure of a lipid droplet protein: The PAT family member TIP47
    • DOI 10.1016/j.str.2004.04.021, PII S0969212604002011
    • Hickenbottom, S. J., A. R. Kimmel, C. Londos, and J. H. Hurley. 2004. Structure of a lipid droplet protein: the PAT family member TIP47. Structure. 12: 1199-1207. (Pubitemid 38900762)
    • (2004) Structure , vol.12 , Issue.7 , pp. 1199-1207
    • Hickenbottom, S.J.1    Kimmel, A.R.2    Londos, C.3    Hurley, J.H.4
  • 44
    • 33646168160 scopus 로고    scopus 로고
    • Lipid droplets: A unified view of a dynamic organelle
    • Martin, S., and R. G. Parton. 2006. Lipid droplets: a unified view of a dynamic organelle. Nat. Rev. Mol. Cell Biol. 7: 373-378.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 373-378
    • Martin, S.1    Parton, R.G.2
  • 45
    • 33947602860 scopus 로고    scopus 로고
    • Chylomicrons and Lipoprotein Lipase at the Endothelial Surface: Bound and GAG-ged?
    • DOI 10.1016/j.cmet.2007.03.003, PII S1550413107000642
    • Ory, D. S. 2007. Chylomicrons and lipoprotein lipase at the endothelial surface: bound and GAG-ged? Cell Metab. 5: 229-231. (Pubitemid 46477857)
    • (2007) Cell Metabolism , vol.5 , Issue.4 , pp. 229-231
    • Ory, D.S.1
  • 46
    • 34248343423 scopus 로고    scopus 로고
    • Characterization of apolipoprotein A-V structure and mode of plasma triacylglycerol regulation
    • DOI 10.1097/MOL.0b013e328133856c, PII 0004143320070600000015
    • Wong, K., and R. O. Ryan. 2007. Characterizatioin of apolipoprotein A-V structure and mode of plasma triacylglycerol regulation. Curr. Opin. Lipidol. 18: 319-324. (Pubitemid 46743057)
    • (2007) Current Opinion in Lipidology , vol.18 , Issue.3 , pp. 319-324
    • Wong, K.1    Ryan, R.O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.