-
5
-
-
34548429964
-
-
For some recent applications of dithiane chemistry in organic synthesis, see
-
For some recent applications of dithiane chemistry in organic synthesis, see: (d) Chen, Y.-L.; Leguijt, R.; Redlich, H. J. Carbohydr. Chem. 2007, 26, 279-303.
-
(2007)
J. Carbohydr. Chem.
, vol.26
, pp. 279-303
-
-
Chen, Y.-L.1
Leguijt, R.2
Redlich, H.3
-
6
-
-
33845968491
-
-
(e) Chen, Y.-L.; Leguijt, R.; Redlich, H.; Fröhlich, R. Synthesis 2006, 4212-4218.
-
(2006)
Synthesis
, pp. 4212-4218
-
-
Chen, Y.-L.1
Leguijt, R.2
Redlich, H.3
Fröhlich, R.4
-
8
-
-
34948896027
-
-
(g) Chen, Y.-L.; Redlich, H.; Bergander, K.; Fröhlich, R. Org. Biomol. Chem. 2007, 5, 3330-3339.
-
(2007)
Org. Biomol. Chem.
, vol.5
, pp. 3330-3339
-
-
Chen, Y.-L.1
Redlich, H.2
Bergander, K.3
Fröhlich, R.4
-
9
-
-
34250870731
-
-
(a) Marion, N.; Díez-González, S.; Nolan, S. P. Angew. Chem., Int. Ed. 2007, 46, 2988-3000.
-
(2007)
Angew. Chem., Int. Ed.
, vol.46
, pp. 2988-3000
-
-
Marion, N.1
Díez-González, S.2
Nolan, S.P.3
-
10
-
-
38349109278
-
-
(b) Enders, D.; Niemeier, O.; Henseler, A. Chem. Rev. 2007, 107, 5606-5655.
-
(2007)
Chem. Rev.
, vol.107
, pp. 5606-5655
-
-
Enders, D.1
Niemeier, O.2
Henseler, A.3
-
11
-
-
0001613906
-
-
Some formal substitutions of α-halogenated esters by carbanion sources were reported: a formal substitution of α-halogenated esters by addition and rearrangement of Grignard reagent
-
Some formal substitutions of α-halogenated esters by carbanion sources were reported: a formal substitution of α-halogenated esters by addition and rearrangement of Grignard reagent: (a) Hussey, A. S.; Herr, R. R. J. Org. Chem. 1959, 24, 843-845.
-
(1959)
J. Org. Chem.
, vol.24
, pp. 843-845
-
-
Hussey, A.S.1
Herr, R.R.2
-
12
-
-
0342826097
-
-
Using organocadmium reagents for substitution of α-bromoesters
-
Using organocadmium reagents for substitution of α-bromoesters: (b) Jones, P. R.; Young, J. R. J. Org. Chem. 1968, 33, 1675-1676.
-
(1968)
J. Org. Chem.
, vol.33
, pp. 1675-1676
-
-
Jones, P.R.1
Young, J.R.2
-
13
-
-
0003722140
-
-
(c) Amano, T.; Yoshikawa, K.; Sano, T.; Ohuchi, Y.; Shiono, M.; Ishiguro, M.; Fujita, Y. Synth. Commun. 1986, 16, 499-507.
-
(1986)
Synth. Commun.
, vol.16
, pp. 499-507
-
-
Amano, T.1
Yoshikawa, K.2
Sano, T.3
Ohuchi, Y.4
Shiono, M.5
Ishiguro, M.6
Fujita, Y.7
-
14
-
-
0029930056
-
-
Using boron reagents for substitution of α-bromoesters
-
Using boron reagents for substitution of α-bromoesters: (d) Cai, J.; Nemoto, H.; Singaram, B.; Yamamoto, Y. Tetrahedron Lett. 1996, 37, 3383-3386.
-
(1996)
Tetrahedron Lett.
, vol.37
, pp. 3383-3386
-
-
Cai, J.1
Nemoto, H.2
Singaram, B.3
Yamamoto, Y.4
-
15
-
-
33244462197
-
-
Co catalyzed coupling reactions between Grignard reagents and α-bromoesters
-
Co catalyzed coupling reactions between Grignard reagents and α-bromoesters: (e) Ohmiya, H.; Yorimitsu, H.; Oshima, K. J. Am. Chem. Soc. 2006, 128, 1886-1889.
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 1886-1889
-
-
Ohmiya, H.1
Yorimitsu, H.2
Oshima, K.3
-
16
-
-
46949098763
-
-
Fe catalyzed coupling reactions between Grignard reagents and α-bromoesters
-
Fe catalyzed coupling reactions between Grignard reagents and α-bromoesters: (f) Fürstner, A.; Martin, R.; Krause, H.; Seidel, G.; Goddard, R.; Lehmann, C. W. J. Am. Chem. Soc. 2008, 130, 8773-8787.
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 8773-8787
-
-
Fürstner, A.1
Martin, R.2
Krause, H.3
Seidel, G.4
Goddard, R.5
Lehmann, C.W.6
-
17
-
-
0018124907
-
-
1 synthons were described
-
1 synthons were described: (a) Mikolajczyk, M.; Grzejszczak, S.; Zatorski, A.; Mlotkowska, B.; Gross, H.; Costisella, B. Tetrahedron 1978, 34, 3081-3088.
-
(1978)
Tetrahedron
, vol.34
, pp. 3081-3088
-
-
Mikolajczyk, M.1
Grzejszczak, S.2
Zatorski, A.3
Mlotkowska, B.4
Gross, H.5
Costisella, B.6
-
19
-
-
0001653298
-
-
(a) Reggelin, M.; Tebben, P.; Hoppe, D. Tetrahedron Lett. 1989, 30, 2915-2918.
-
(1989)
Tetrahedron Lett.
, vol.30
, pp. 2915-2918
-
-
Reggelin, M.1
Tebben, P.2
Hoppe, D.3
-
20
-
-
0000070547
-
-
(b) Tebben, P.; Reggelin, M.; Hoppe, D. Tetrahedron Lett. 1989, 30, 2919-2922.
-
(1989)
Tetrahedron Lett.
, vol.30
, pp. 2919-2922
-
-
Tebben, P.1
Reggelin, M.2
Hoppe, D.3
-
21
-
-
0031047756
-
-
(c) Hoppe, D.; Tebben, P.; Reggelin, M.; Bolte, M. Synthesis 1997, 183-190.
-
(1997)
Synthesis
, pp. 183-190
-
-
Hoppe, D.1
Tebben, P.2
Reggelin, M.3
Bolte, M.4
-
24
-
-
60149095699
-
-
A recent example demonstrating the efficiency of one-pot reaction for synthesis of (-)-oseltamivir
-
A recent example demonstrating the efficiency of one-pot reaction for synthesis of (-)-oseltamivir: Ishikawa, H.; Suzuki, T.; Hayashi, Y. Angew. Chem., Int. Ed. 2009, 48, 1304-1307.
-
(2009)
Angew. Chem., Int. Ed.
, vol.48
, pp. 1304-1307
-
-
Ishikawa, H.1
Suzuki, T.2
Hayashi, Y.3
-
25
-
-
0003445429
-
-
See for example: Jacobsen, E. N., Pfaltz, A., Yamamoto, H., Eds; Springer: Berlin, Chapter 5.1
-
See for example: Brown, J. M. In Comprehensive Asymmetric Catalysis; Jacobsen, E. N., Pfaltz, A., Yamamoto, H., Eds; Springer: Berlin, 1999; Vol.1, Chapter 5.1
-
(1999)
Comprehensive Asymmetric Catalysis
, vol.1
-
-
Brown, J.M.1
-
26
-
-
0041738169
-
-
See for example
-
See for example: (a) Hayashi, T.; Yamasaki, K. Chem. Rev. 2003, 103, 2829-2844.
-
(2003)
Chem. Rev.
, vol.103
, pp. 2829-2844
-
-
Hayashi, T.1
Yamasaki, K.2
-
28
-
-
39149131680
-
-
Some conjugate addition of stoichiometrical lithium organocuprate to α-oxygenated-α,β-unsatured carbonyl compounds are known
-
Some conjugate addition of stoichiometrical lithium organocuprate to α-oxygenated-α,β-unsatured carbonyl compounds are known: (a) Brehm, M.; Göckel, V. H; Jarglis, P.; Lichtenthaler, F. W. Tetrahedron: Asymmetry 2008, 19, 358-373.
-
(2008)
Tetrahedron: Asymmetry
, vol.19
, pp. 358-373
-
-
Brehm, M.1
Göckel, V.H.2
Jarglis, P.3
Lichtenthaler, F.W.4
-
29
-
-
0001263521
-
-
(b) Verdaguer, X.; Vázquez, J.; Fuster, G.; Bernardes- Génisson, V.; Greene, A. E.; Moyano, A.; Pericás, M. A.; Riera, A. J. Org. Chem. 1998, 63, 7037-7052.
-
(1998)
J. Org. Chem.
, vol.63
, pp. 7037-7052
-
-
Verdaguer, X.1
Vázquez, J.2
Fuster, G.3
Bernardes-Génisson, V.4
Greene, A.E.5
Moyano, A.6
Pericás, M.A.7
Riera, A.8
-
30
-
-
0025179909
-
-
(c) Denmark, S. E.; Dappen, M. S.; Sear, N. L.; Jacobs, R. T. J. Am. Chem. Soc. 1990, 112, 3466-3474.
-
(1990)
J. Am. Chem. Soc.
, vol.112
, pp. 3466-3474
-
-
Denmark, S.E.1
Dappen, M.S.2
Sear, N.L.3
Jacobs, R.T.4
-
32
-
-
0027050075
-
-
Several copper-catalyzed conjugate addition reactions to α-oxygenated-α,β-unsatured carbonyl compounds are known for certain substrates
-
Several copper-catalyzed conjugate addition reactions to α-oxygenated-α,β-unsatured carbonyl compounds are known for certain substrates: (e) Cativiela, C.; Diaz-de-Villegas, M. D.; Galvez, J. A. Can. J. Chem. 1992, 70, 2325-2328.
-
(1992)
Can. J. Chem.
, vol.70
, pp. 2325-2328
-
-
Cativiela, C.1
Diaz-de-Villegas, M.D.2
Galvez, J.A.3
-
34
-
-
0033531979
-
-
(g) Cardillo, G.; Gentilucci, L.; Tolomelli, A.; Tomasini, C. Tetrahedron 1999, 55, 6231-6242.
-
(1999)
Tetrahedron
, vol.55
, pp. 6231-6242
-
-
Cardillo, G.1
Gentilucci, L.2
Tolomelli, A.3
Tomasini, C.4
-
35
-
-
66249122314
-
-
According to unpublished results in our group, substituent R on structure 1 can be either Cb or 2,2,4,4-tetramethyl-1,3-oxazolidin-3-carbonyl (Cby). Generally Cb leads to slightly higher yield for the addition reaction leading to structure 2
-
According to unpublished results in our group, substituent R on structure 1 can be either Cb or 2,2,4,4-tetramethyl-1,3-oxazolidin-3-carbonyl (Cby). Generally Cb leads to slightly higher yield for the addition reaction leading to structure 2.
-
-
-
-
36
-
-
0000242594
-
-
Ni or Pd catalyzed substitution and reduction of α,β- unsaturated sulfone
-
Ni or Pd catalyzed substitution and reduction of α,β- unsaturated sulfone: (a) Fabre, J.-L.; Julia, M. Tetrahedron Lett. 1983, 24, 4311-4314.
-
(1983)
Tetrahedron Lett.
, vol.24
, pp. 4311-4314
-
-
Fabre, J.-L.1
Julia, M.2
-
37
-
-
0002442551
-
-
Ni catalyzed substitution of α,β-unsaturated sulfone was reported
-
Ni catalyzed substitution of α,β-unsaturated sulfone was reported: (b) Fabre, J. L.; Julia, M.; Verpeaux, J.-N. Bull. Soc. Chim. Fr 1985, 5, 762-771.
-
(1985)
Bull. Soc. Chim. Fr
, vol.5
, pp. 762-771
-
-
Fabre, J.L.1
Julia, M.2
Verpeaux, J.-N.3
-
38
-
-
66249085459
-
-
Unpublished results in this group
-
Unpublished results in this group.
-
-
-
-
39
-
-
51049122142
-
-
For review, see
-
For review, see: Alexakis, A.; Bäckvall, J. E; Krause, N.; Pàmies, O.; Diéguez, M. Chem. Rev 2008, 108, 2796-2823.
-
(2008)
Chem. Rev
, vol.108
, pp. 2796-2823
-
-
Alexakis, A.1
Bäckvall, J.E.2
Krause, N.3
Pàmies, O.4
Diéguez, M.5
-
40
-
-
66249115885
-
-
Schlosser, M., Ed.; John Wiley & Sons Inc: New York
-
Lipschutz, B. H. In Organometallics in Synthesis - A Manual, 2nd ed.; Schlosser, M., Ed.; John Wiley & Sons Inc: New York, 2002; pp 666-815.
-
(2002)
Organometallics in Synthesis - A Manual, 2nd Ed.
, pp. 666-815
-
-
Lipschutz, B.H.1
-
41
-
-
0000898481
-
-
Hoppe, D.; Hanko, R.; Brönneke, A.; Lichtenberg, F.; van Huelsen, E. Chem. Ber. 1985, 118, 2822-2851.
-
(1985)
Chem. Ber.
, vol.118
, pp. 2822-2851
-
-
Hoppe, D.1
Hanko, R.2
Brönneke, A.3
Lichtenberg, F.4
Van Huelsen, E.5
-
42
-
-
0000832426
-
-
For the lithiation of the enol carbamates 4a, b and c, see
-
For the lithiation of the enol carbamates 4a, b and c, see: (a) Sengupta, S.; Snieckus, V. J. Org. Chem. 1990, 55, 5680-5683.
-
(1990)
J. Org. Chem.
, vol.55
, pp. 5680-5683
-
-
Sengupta, S.1
Snieckus, V.2
-
43
-
-
66249092696
-
-
Dissertation, University of Kiel
-
(b) Peschke, B. Dissertation, University of Kiel, 1991.
-
(1991)
-
-
Peschke, B.1
-
46
-
-
84990134356
-
-
For discussion of lithiated sulfones and their H/D exchange experiments, see
-
For discussion of lithiated sulfones and their H/D exchange experiments, see: Boche, G. Angew. Chem., Int. Ed. 1989, 28, 277-297.
-
(1989)
Angew. Chem., Int. Ed.
, vol.28
, pp. 277-297
-
-
Boche, G.1
-
47
-
-
66249131953
-
-
For Ni catalyzed substitution of enol carbamate by Grignard reagent: see ref 17c
-
For Ni catalyzed substitution of enol carbamate by Grignard reagent: see ref 17c.
-
-
-
-
49
-
-
33645396909
-
-
Marshall, J. A.; Yanik, M. M.; Adams, N. D.; Ellis, K. C.; Chobanian, H. R. Org. Synth. 2005, 81, 157-170.
-
(2005)
Org. Synth.
, vol.81
, pp. 157-170
-
-
Marshall, J.A.1
Yanik, M.M.2
Adams, N.D.3
Ellis, K.C.4
Chobanian, H.R.5
-
51
-
-
0001514892
-
-
Taylor, S. K.; Clark, D. L.; Heinz, K. L.; Schramm, S. B.; Westermann, C. D.; Barnell, K. K. J. Org. Chem. 1983, 48, 592-596.
-
(1983)
J. Org. Chem.
, vol.48
, pp. 592-596
-
-
Taylor, S.K.1
Clark, D.L.2
Heinz, K.L.3
Schramm, S.B.4
Westermann, C.D.5
Barnell, K.K.6
|