Towards an exhaustive sampling of the configurational spaces of the two forms of the peptide hormone guanylin

Journal of Biomolecular Structure and Dynamics

Volumn 13, Issue 5, 1996, Pages 741-751

  de Groot, B L ^a   Amadei, A ^a   van Aalten, D M F ^b   Berendsen, H J C ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GUANYLIN; PEPTIDE HORMONE;

ARTICLE; MOLECULAR DYNAMICS; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; SAMPLING;

EID: 0029967692     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.1996.10508888     Document Type: Article

References (15)

1. Skelton, N. J., Garcia, K. C., Goeddel, D. V., Quann, C., and Burnier, J. P., 1994. Determination of the solution structure of the peptide hormone guanylin:Observation of a novel form of topological stereoisomerism. Biochemistry, 33:13581–13592.
2. Currie, M. G., Fok, K. F., Kato, J., Moore, R. J., Hamra, F. K., Duffin, K. L., and Smith, C. E., 1992. Guanylin:an endogenous activator of intestinal guanylate cyclase. Proc. Natl. Acad. Sci. USA, 89:947–951.
3. Forte, L. R., and Currie, M. G., 1995. Guanylin:a peptide regulator of epithelal transport. The FASEB journal, 9:643–650.
4. Field, M., Graf, L. H., Jr, Laird, W. J., and Smith, P. L., 1978. Heat-stable enterotoxin of Eschericia coli:in vitro effects on guanylate cyclase activity, cyclic GMP concentration and ion transport in small intestine. Proc. Natl. Acad. Sci. USA, 75:2800–2804.
5. de Sauvage, F. J., Keshav, S., Kuang, W-J, Gillet, N., Henzel, W., and Goeddel, D. V., 1992. Precursor structure, expression and tissue distributution of human guanylin. Proc. Natl. Acad. Sci. USA, 89:9089–9093.
6. Amadei, A., Linssen, A. B.M., and Berendsen, H. J.C., 1993. Essential Dynamics of Proteins. Proteins:Str., Funct., and Gen., 17:412–425.
7. Amadei, A., Linssen, A. B.M., de Groot, B. L., van Aalten, D. M.F., and Berendsen, H. J.C., 1996. An efficient method for sampling the essential subspace of proteins. J. Biom. Str. Dyn., 13:615–625.
8. Berendsen, H. J. C., Postma, J. P. M., van Gunsteren, W. F., and Hermans, J., 1981. Intermolecular Forces Edited by:Pullmann, B., 331Dordrecht:Reidel. page
9. Berendsen, H. J.C., Postma, J. P.M., DiNola, A., and Haak, J. R., 1984. Molecular dynamics with coupling to an external bath. J. Chem. Phys., 81:3684–3690.
10. Ryckaert, J. P., Ciccotti, G., and Berendsen, H. J.C., 1977. Numerical Integration of the Cartesian Equations of Motion of a System with Constraints; Molecular Dynamics of n-Alkanes. J. Comp. Phys., 23:327–341.
11. van Gunsteren, W. F., and Berendsen, H. J.C., 1987. Gromos manual. The Netherlands:BIOMOS Biomolecular Software, Laboratory of Physical Chemistry, University of Groningen.
12. Vriend, G., 1990. WHAT IF:a molecular modeling and drug design program. J. Mol. Graph., 8:52–56.
13. Garcia, A. E., 1992. Large-amplitude nonlinear motions in proteins. Phys. Rev. Lett., 68:2696–2699.
14. Amadei, A., Linssen, A. B. M., de Groot, B. L., and Berendsen, H. J. C., 1995. “ Essential degrees of freedom of proteins. In:”. In Modelling of Biomolecular Structures and Mechanisms Edited by:Pullmann, A., 85–93. The Netherlands editor, pages Kluwer
15. Scheek, R. M., van Nuland, N. A.J, de Groot, B. L., and Amadei, A., 1995. Structure from NMR and molecular dynamics:distance restraining inhibits motion in the essential subspace. J. Biomol. NMR., 6:106–111.