Corneal molecular and cellular biology update for the refractive surgeon

Journal of Refractive Surgery

Volumn 25, Issue 5, 2009, Pages 459-466

  Salomao, Marcella Q ^a   Wilson, Steven E ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOMYCIN C; TRANSFORMING GROWTH FACTOR BETA;

BONE MARROW; CELL DENSITY; CELL INTERACTION; CELL POPULATION; CELL PROLIFERATION; CORNEA CELL; CYTOLOGY; ENERGY; EPITHELIUM; HEALING; HUMAN; INFLAMMATORY CELL; KERATOMILEUSIS; LASER SURGERY; MOLECULAR INTERACTION; MYOFIBROBLAST; NECROSIS; PHOTOREFRACTIVE KERATECTOMY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; REFRACTIVE SURGERY; REVIEW; STEM CELL; STROMA; TREATMENT OUTCOME;

ALKYLATING AGENTS; APOPTOSIS; CORNEA; CORNEAL OPACITY; CORNEAL SURGERY, LASER; HUMANS; LASERS, EXCIMER; MITOMYCIN; WOUND HEALING;

EID: 66149173538     PISSN: 1081597X     EISSN: None     Source Type: Journal    
DOI: 10.3928/1081597X-20090422-09     Document Type: Review

References (19)

1. Wilson SE, He YG, Weng J, Li Q, McDowall AW, Vital M, Chwang EL. Epithelial injury induces keratocyte apoptosis: hypothesized role for the interleukin-1 system in the modulation of corneal tissue organization and wound healing. Exp Eye Res. 1996;62:325-327. (Pubitemid 26151425)
2. Mohan RR, Hutcheon AE, Choi R, Hong J, Lee J, Mohan RR, Ambrósio R Jr, Zieske JD, Wilson SE. Apoptosis, necrosis, proliferation, and myofibroblast generation in the stroma following LASIK and PRK. Exp Eye Res. 2003;76:71-87. (Pubitemid 36268717)
3. Wilson SE. Molecular cell biology for the refractive corneal surgeon: programmed cell death and wound healing. J Refract Surg. 1997;13:171-175. (Pubitemid 27203276)
4. Netto MV, Mohan RR, Medeiros FW, Dupps WJ Jr, Sinha S, Krueger RR, Stapleton WM, Rayborn M, Suto C, Wilson SE. Femtosecond laser and microkeratome corneal flaps: comparison of stromal wound healing and inflammation. J Refract Surg. 2007;23:667-676. (Pubitemid 47424672)
5. Stonecipher KG, Dishler JG, Ignacio TS, Binder PS. Transient light sensitivity after femtosecond laser flap creation: clinical findings and management. J Cataract Refract Surg. 2006;32:91-94. (Pubitemid 43330055)
6. Muñoz G, Albarrán-Diego C, Sakla HF, Javaloy J, Alió JL. Transient light-sensitivity syndrome after laser in situ keratomileusis with the femtosecond laser: incidence and prevention. J Cataract Refract Surg. 2006;32:2075-2079.
7. Rajan MS, Jaycock P, O'Brart D, Nystrom HH, Marshall J. A long-term study of photorefractive keratectomy; 12-year follow-up. Ophthalmology. 2004;111:1813-1824. (Pubitemid 39311831)
8. El-Maghraby A, Salah T, Waring GO III, Klyce SD, Ibrahim O. Randomized bilateral comparison of excimer laser in situ keratomileusis and photorefractive keratectomy for 2.50 to 8.00 diopters of myopia. Ophthalmology. 1999;106:447-457. (Pubitemid 30191577)
9. Hersh PS, Stulting RD, Steinert RF, Waring GO III, Thompson KP, O'Connell M, Doney K, Schein OD. Results of phase III excimer laser photorefractive keratectomy for myopia. The Summit PRK Study Group. Ophthalmology. 1997;104:1535-1553. (Pubitemid 28053450)
10. Møller-Pedersen T, Cavanagh HD, Petroll WM, Jester JV. Corneal haze development after PRK is regulated by volume of stromal tissue removal. Cornea. 1998;17:627-639. (Pubitemid 28511910)
11. Vinciguerra P, Azzolini M, Airaghi P, Radice P, De Molfetta V. Effect of decreasing surface and interface irregularities after photorefractive keratectomy and laser in situ keratomileusis on optical and functional outcomes. J Refract Surg. 1998;14:S199-S203. (Pubitemid 28193634)
12. Netto MV, Mohan RR, Sinha S, Sharma A, Dupps W, Wilson SE. Stromal haze, myofibroblasts, and surface irregularity after PRK. Exp Eye Res. 2006;82:788-797. (Pubitemid 43170879)
13. Wilson SE, Chaurasia SS, Medeiros FW. Apoptosis in the initiation, modulation and termination of the corneal wound healing response. Exp Eye Res. 2007;85:305-311. (Pubitemid 47259060)
14. Majmudar PA, Forstot SL, Dennis RF, Nirankari VS, Damiano RE, Brenart R, Epstein RJ. Topical mitomycin-C for subepithelial fibrosis after refractive corneal surgery. Ophthalmology. 2000;107:89-94. (Pubitemid 30210188)
15. Kim TI, Tchah H, Lee SA, Sung K, Cho BJ, Kook MS. Apoptosis in keratocytes caused by mitomycin C. Invest Ophthalmol Vis Sci. 2003;44:1912-1917. (Pubitemid 36522777)
16. Netto MV, Mohan RR, Sinha S, Sharma A, Gupta PC, Wilson SE. Effect of prophylactic and therapeutic mitomycin C on corneal apoptosis, cellular proliferation, haze, and long-term keratocyte density in rabbits. J Refract Surg. 2006;22:562-574. (Pubitemid 43911949)
17. Møller-Pedersen T, Cavanagh HD, Petroll WM, Jester JV. Neutralizing antibody to TGFbeta modulates stromal fibrosis but not regression of photoablative effect following PRK. Curr Eye Res. 1998;17:736-747. (Pubitemid 28367786)
18. Thornton I, Xu M, Krueger RR. Comparison of standard (0.02%) and low dose (0.002%) mitomycin C in the prevention of corneal haze following surface ablation for myopia. J Refract Surg. 2008;24:S68-S76.
19. Qazi MA, Johnson TW, Pepose JS. Development of late-onset subepithelial corneal haze after laser-assisted subepithelial keratectomy with prophylactic intraoperative mitomycin-C. Case report and literature review. J Cataract Refract Surg. 2006;32:1573-1578. (Pubitemid 44247487)