-
1
-
-
27144500125
-
Germ cell tumors of the testis
-
DOI 10.1245/ASO.2005.01.013
-
Carver BS, Sheinfeld J. Germ cell tumors of the testis. Ann Surg Oncol 2005;11:1-10. (Pubitemid 41504219)
-
(2005)
Annals of Surgical Oncology
, vol.12
, Issue.11
, pp. 871-880
-
-
Carver, B.S.1
Sheinfeld, J.2
-
3
-
-
10144262544
-
High-dose chemotherapy as salvage treatment in germ cell tumors: A multivariate analysis of prognostic variables
-
Beyer J, Kramar A, Mandanas R, et al. Highdose chemotherapy as salvage treatment in germ cell tumors: a multivariate analysis of prognostic variables. J Clin Oncol 1996;14: 2638-2645 (Pubitemid 26329647)
-
(1996)
Journal of Clinical Oncology
, vol.14
, Issue.10
, pp. 2638-2645
-
-
Beyer, J.1
Kramar, A.2
Mandanas, R.3
Linkesch, W.4
Greinix, A.5
Droz, J.P.6
Pico, J.L.7
Diehl, A.8
Bokemeyer, C.9
Schmoll, H.J.10
Nichols, C.R.11
Einhorn, L.H.12
Siegert, W.13
-
4
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971;285:1182-1186
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
5
-
-
30744479430
-
Angiogenesis in life, disease and medicine
-
DOI 10.1038/nature04478, PII NATURE04478
-
Carmeliet P. Angiogenesis in life, disease and medicine. Nature 2005;438:932-936 (Pubitemid 43093958)
-
(2005)
Nature
, vol.438
, Issue.7070
, pp. 932-936
-
-
Carmeliet, P.1
-
6
-
-
0037221174
-
Role of growth factors and their receptors in proliferation of microvascular endothelial cells
-
DOI 10.1002/jemt.10245
-
Shuhardja A, Hoffman H. Role of growth factors and their receptors on proliferation of microvascular endothelial cells. Microsc Res Tech 2003; 60:70-75 (Pubitemid 36055235)
-
(2003)
Microscopy Research and Technique
, vol.60
, Issue.1
, pp. 70-75
-
-
Suhardja, A.1
Hoffman, H.2
-
8
-
-
78650874372
-
SU11248 inhibits c-KIT and platelet-derived growth factor receptor-β in preclinical models of human small cell lung cancer
-
Abrams TJ, Lee LB, Murray LJ, Pryer NK, Cherrington JM. SU11248 inhibits c-KIT and platelet-derived growth factor receptor-β in preclinical models of human small cell lung cancer. Mol Cancer Ther 2003;2:471-478
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 471-478
-
-
Abrams, T.J.1
Lee, L.B.2
Murray, L.J.3
Pryer, N.K.4
Cherrington, J.M.5
-
9
-
-
0038204144
-
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
-
DOI 10.1182/blood-2002-07-2307
-
O'Farrell AM, Abrams TJ, Yuen HA, et al. SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood 2003;101:3597-3605 (Pubitemid 36857948)
-
(2003)
Blood
, vol.101
, Issue.9
, pp. 3597-3605
-
-
O'Farrell, A.-M.1
Abrams, T.J.2
Yuen, H.A.3
Ngai, T.J.4
Louie, S.G.5
Yee, K.W.H.6
Wong, L.M.7
Hong, W.8
Lee, L.B.9
Town, A.10
Smolich, B.D.11
Manning, W.C.12
Murray, L.J.13
Heinrich, M.C.14
Cherrington, J.M.15
-
10
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/ pharmacodynamic relationship
-
Mendel DB, Laird AD, Xin X, et al. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/ pharmacodynamic relationship. Clin Cancer Res 2003;9:327-337
-
(2003)
Clin Cancer Res
, vol.9
, pp. 327-337
-
-
Mendel, D.B.1
Laird, A.D.2
Xin, X.3
-
11
-
-
33646432734
-
Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate
-
Prenen H, Cools J, Mentens N, et al. Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate. Clin Cancer Res 2006;12:2622-2627
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2622-2627
-
-
Prenen, H.1
Cools, J.2
Mentens, N.3
-
12
-
-
38449097166
-
Antiangiogenic and anti-invasive effects of sunitinib onexperimen tal human glioblastoma
-
Boüard S, Herlin P, Christensen JG, et al. Antiangiogenic and anti-invasive effects of sunitinib onexperimen tal human glioblastoma. Neurooncol 2007;9:412-423
-
(2007)
Neurooncol
, vol.9
, pp. 412-423
-
-
Boüard, S.1
Herlin, P.2
Christensen, J.G.3
-
13
-
-
33644833910
-
Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma
-
DOI 10.1200/JCO.2005.02.2574
-
Motzer RJ, Michaelson MD, Redman BG, et al. Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma. J Clin Oncol 2006;24:16-24. (Pubitemid 46630489)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.1
, pp. 16-24
-
-
Motzer, R.J.1
Michaelson, M.D.2
Redman, B.G.3
Hudes, G.R.4
Wilding, G.5
Figlin, R.A.6
Ginsberg, M.S.7
Kim, S.T.8
Baum, C.M.9
Deprimo, S.E.10
Li, J.Z.11
Bello, C.L.12
Theuer, C.P.13
George, D.J.14
Rini, B.I.15
-
14
-
-
33644847440
-
Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer
-
DOI 10.1200/JCO.2005.02.2194
-
Faivre S, Delbaldo C, Vera K, et al. Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer. J Clin Oncol 2006;24:25-35. (Pubitemid 46630490)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.1
, pp. 25-35
-
-
Faivre, S.1
Delbaldo, C.2
Vera, K.3
Robert, C.4
Lozahic, S.5
Lassau, N.6
Bello, C.7
Deprimo, S.8
Brega, N.9
Massimini, G.10
Armand, J.-P.11
Scigalla, P.12
Raymond, E.13
-
15
-
-
33947504730
-
Sunitinib: From rational design to clinical efficacy
-
DOI 10.1200/JCO.2006.06.3602
-
Chow L, Eckhardt S. Sunitinib: from rational design to clinical efficacy. J Clin Oncol 2007;25: 2858-2859 (Pubitemid 350002890)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.7
, pp. 884-896
-
-
Chow, L.Q.M.1
Eckhardt, S.G.2
-
16
-
-
33947423448
-
Approval summary: Sunitinib for the treatment of imatinib refractory or intolerant gastrointestinal stromal tumors and advanced renal cell carcinoma
-
DOI 10.1158/1078-0432.CCR-06-2328
-
Goodman VL, Rock EP, Dagher R, et al. Approval summary: sunitinib for the treatment of imatinib refractory or intolerant gastrointestinal stromal tumors and advanced renal cell carcinoma. Clin Cancer Res 2007;13:1367-1373 (Pubitemid 46450424)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.5
, pp. 1367-1373
-
-
Goodman, V.L.1
Rock, E.P.2
Dagher, R.3
Ramchandani, R.P.4
Abraham, S.5
Gobburu, J.V.S.6
Booth, B.P.7
Verbois, S.L.8
Morse, D.E.9
Liang, C.Y.10
Chidambaram, N.11
Jiang, J.X.12
Tang, S.13
Mahjoob, K.14
Justice, R.15
Pazdur, R.16
-
17
-
-
34548316976
-
Molecular basis for sunitinib efficacy and future clinical development
-
DOI 10.1038/nrd2380, PII NRD2380
-
Faivre S, Demetri G, Sargent W, Raymond E. Molecular basis for sunitinib efficacy and future clinical development. Nat Rev Drug Discov 2007; 6:734-745 (Pubitemid 47338181)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.9
, pp. 734-745
-
-
Faivre, S.1
Demetri, G.2
Sargent, W.3
Raymond, E.4
-
18
-
-
24944431729
-
Amplification and overexpression of the KIT gene is associated with progression in the seminoma subtype of testicular germ cell tumors of adolescents and adults
-
DOI 10.1158/0008-5472.CAN-05-0471
-
McIntyre A, Summersgill B, Grygalewicz B, et al. Amplificationan d overexpression of the c-KIT gene is associated with progression in the seminoma subtype of testicular germ cell tumors of adolescents and adults. Cancer Res 2005;65:8085-8089 (Pubitemid 41330569)
-
(2005)
Cancer Research
, vol.65
, Issue.18
, pp. 8085-8089
-
-
McIntyre, A.1
Summersgill, B.2
Grygalewicz, B.3
Gillis, A.J.M.4
Stoop, J.5
Van Gurp, R.J.H.L.M.6
Dennis, N.7
Fisher, C.8
Huddart, R.9
Cooper, C.10
Clark, J.11
Oosterhuis, J.W.12
Looijenga, L.H.J.13
Shipley, J.14
-
19
-
-
9444223256
-
Neovascularization in human germ cell tumors correlates with a marked increase in the expression of the vascular endothelial growth factor but not the placenta-derived growth factor
-
Viglietto G, Romano A, Maglione D, et al. Neovascularizationin humangerm cell tumors correlates with a marked increase in the expression of the vascular endothelial growth factor but not the placenta-derived growth factor. Oncogene 1996;13:577-587 (Pubitemid 26283854)
-
(1996)
Oncogene
, vol.13
, Issue.3
, pp. 577-587
-
-
Viglietto, G.1
Romano, A.2
Maglione, D.3
Rambaldi, M.4
Paoletti, I.5
Lago, C.T.6
Califano, D.7
Monaco, C.8
Mineo, A.9
Santelli, G.10
Manzo, G.11
Botti, G.12
Chiappetta, G.13
Persico, M.G.14
-
20
-
-
18344362452
-
Expression of platelet-derived growth factor-A (PDGF-A), PDGF-B, and PDGF receptor-α and -β during human testicular development and disease
-
DOI 10.1210/jc.87.5.2310
-
Basciani S, Mariani S, Arizzi M, et al. Expression of platelet-derived growth factor-A (PDGF-A), PDGF-B, and PDGF receptor-α and -β during human testicular development and disease. J Clin Endocrinol Metab 2002;87: 2310-2319 (Pubitemid 34521525)
-
(2002)
Journal of Clinical Endocrinology and Metabolism
, vol.87
, Issue.5
, pp. 2310-2319
-
-
Basciani, S.1
Mariani, S.2
Arizzi, M.3
Ulisse, S.4
Rucci, N.5
Jannini, E.A.6
Rocca, C.D.7
Manicone, A.8
Carani, C.9
Spera, G.10
Gnessi, L.11
-
21
-
-
0033961811
-
Tumor markers at the time of recurrence in patients with germ cell tumors
-
DOI 10.1002/(SICI)1097-0142(20000101)88:1<162::AID-CNCR22>3.0.CO;2- V
-
Trigo JM, Tabernero JM, Paz-Ares L, et al. Tumor markers at the time of recurrence in patients with germ cell tumors. Cancer 2000;88:162-168 (Pubitemid 30027692)
-
(2000)
Cancer
, vol.88
, Issue.1
, pp. 162-168
-
-
Trigo, J.M.1
Tabernero, J.M.2
Paz-Ares, L.3
Garcia-Llano, J.L.4
Mora, J.5
Lianes, P.6
Esteban, E.7
Salazar, R.8
Lopez-Lopez, J.J.9
Cortes-Funes, H.10
-
22
-
-
33644660123
-
Risk-adapted management for patients with clinical stage I seminoma: The second Spanish Germ Cell Cancer Cooperative Group study
-
DOI 10.1200/JCO.2005.01.9810
-
Aparicio J, Germà JR, García del Muro X, et al. Risk-adapted management for patients with clinical stage I seminoma: the second Spanish Germ Cell Cancer Cooperative Group Study. J Clin Oncol 2005;23:8717-8723 (Pubitemid 46211516)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.34
, pp. 8717-8723
-
-
Aparicio, J.1
Germa, J.R.2
Del Muro, X.G.3
Maroto, P.4
Arranz, J.A.5
Saenz, A.6
Barnadas, A.7
Dorca, J.8
Guma, J.9
Olmos, D.10
Bastus, R.11
Carles, J.12
Almenar, D.13
Sanchez, M.14
Paz-Ares, L.15
Satrustegui, J.J.16
Mellado, B.17
Balil, A.18
Lopez-Brea, M.19
Sanchez, A.20
more..
-
23
-
-
0029617282
-
Alpha-fetoprotein-concanavalin a binding as a marker to discriminate between germ cell tumours and liver diseases
-
DOI 10.1016/0959-8049(95)00485-8
-
Mora J, Gascón N, Tabernero JM, Germà JR, González F. α-Fetoprotein-concanavalin A binding as a marker to discriminate between germ cell tumours and liver diseases. Eur J Cancer 1995;31:2239-2242 (Pubitemid 26050565)
-
(1995)
European Journal of Cancer Part A: General Topics
, vol.31
, Issue.13-14
, pp. 2239-2242
-
-
Mora, J.1
Gascon, N.2
Tabernero, J.M.3
Germa, J.R.4
Gonzalez, F.5
-
24
-
-
0029744423
-
Different hCG assays to measure ectopic hCG secretion in bladder carcinoma patients
-
Mora J, Gascón N, Tabernero JM, Rodríguez- Espinosa J, González-Sastre F. Different hCG assays to measure ectopic hCG secretionin bladder carcinoma patients. Br J Cancer 1996; 74:1081-1084 (Pubitemid 26333910)
-
(1996)
British Journal of Cancer
, vol.74
, Issue.7
, pp. 1081-1084
-
-
Mora, J.1
Gascon, N.2
Tabernero, J.M.3
Rodriguez-Espinosa, J.4
Gonzalez-Sastre, F.5
-
25
-
-
0037294708
-
Serum levels of basic fibroblast growth factor reflect disseminated disease in patients with testicular germ cell tumors
-
Bentas W, Beecken WD, Glienke W, Binder J, Schuldes H. Serum levels of basic fibroblast factor reflects disseminated disease in patients with testicular germ cell tumors. Urol Res 2003;30:390-393 (Pubitemid 36285657)
-
(2003)
Urological Research
, vol.30
, Issue.6
, pp. 390-393
-
-
Bentas, W.1
Beecken, W.-D.2
Glienke, W.3
Binder, J.4
Schuldes, H.5
-
26
-
-
10744223148
-
Marked increase of the growth factors pleiotrophin and fibroblast growth factor-2 in serum of testicular cancer patients
-
DOI 10.1093/annonc/mdg416
-
Aigner A, Brachmann P, Beyer J, et al. Marked increase of the growth factors pleiotrophin and fibroblast growth factor-2 inserum of testicular cancer patients. Ann Oncol 2003;14:1525-1529 (Pubitemid 37304608)
-
(2003)
Annals of Oncology
, vol.14
, Issue.10
, pp. 1525-1529
-
-
Aigner, A.1
Brachmann, P.2
Beyer, J.3
Jager, R.4
Raulais, D.5
Vigny, M.6
Neubauer, A.7
Heidenreich, A.8
Weinknecht, S.9
Czubayko, F.10
Zugmaier, G.11
-
27
-
-
0033559229
-
Expression of vascular endothelial growth factor in patients with testicular germ cell tumors as an indicator of metastatic disease
-
DOI 10.1002/(SICI)1097-0142(19990315)85:6<1323::AID-CNCR15>3.0. CO;2-G
-
Fukuda S, Shirahama T, Imazono Y, et al. Expression of vascular endothelial growth factor in patients with testicular germ cell tumors as an indicator of metastatic disease. Cancer 1999;85:1323-1330 (Pubitemid 29125086)
-
(1999)
Cancer
, vol.85
, Issue.6
, pp. 1323-1330
-
-
Fukuda, S.1
Shirahama, T.2
Imazono, Y.3
Tsushima, T.4
Ohmori, H.5
Kayajima, T.6
Take, S.7
Nishiyama, K.8
Yonezawa, S.9
Akiba, S.10
Akiyama, S.-I.11
Ohi, Y.12
-
28
-
-
0037884918
-
Growth regulatory factors and signalling proteins in testicular germ cell tumours
-
DOI 10.1034/j.1600-0463.2003.11101251.x
-
Devouassoux-Shisheboran M , Mauduit C, Tabone E, Droz JP, Benahmed M. Growth regulatory factors and signalling proteins in testicular germ cell tumors. APMIS 2003;111:212-224 (Pubitemid 36566691)
-
(2003)
APMIS
, vol.111
, Issue.1
, pp. 212-224
-
-
Devouassoux-Shisheboran, M.1
Mauduit, C.2
Tabone, E.3
Pierre Droz, J.4
Benahmed, M.5
-
29
-
-
12444297983
-
The receptor tyrosine kinase inhibitor SU11248 impedes endothelial cell migration, tubule formation, and blood vessel formation in vivo, but has little effect on existing tumor vessels
-
Osusky KL, Hallahan DE, Fu A, Ye F, Shyr Y, Geng L. The receptor tyrosine kinase inhibitor SU11248 impedes endothelial cell migration, tubule formation, and blood vessel formation in vivo, but has little effect on existing tumor vessels. Angiogenesis 2004;7:225-233
-
(2004)
Angiogenesis
, vol.7
, pp. 225-233
-
-
Osusky, K.L.1
Hallahan, D.E.2
Fu, A.3
Ye, F.4
Shyr, Y.5
Geng, L.6
-
30
-
-
0036847703
-
Inhibition of platelet-derived growth factor-mediated proliferation of osteosarcoma cells by the novel tyrosine kinase inhibitor STI571
-
McGary EC, Weber K, Mills L, et al. Inhibition of platelet-derived growth factor-mediated proliferation of osteosarcoma cells by the novel tyrosine kinase inhibitor STI571. Clin Cancer Res 2002;8:3584-3591 (Pubitemid 35340737)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.11
, pp. 3584-3591
-
-
McGary, E.C.1
Weber, K.2
Mills, L.3
Doucet, M.4
Lewis, V.5
Lev, D.C.6
Fidler, I.J.7
Bar-Eli, M.8
-
31
-
-
33745098620
-
Contribution of individual targets to the antitumor efficacy of the multitargeted receptor tyrosine kinase inhibitor SU11248
-
DOI 10.1158/1535-7163.MCT-03-0156
-
Potapova O, Laird A, Nannini M, et al. Contribution of individual targets to the antitumor efficacy of the multitargeted receptor tyrosine kinase inhibitor SU11248. Mol Cancer Ther 2006; 5:1280-1288 (Pubitemid 43881321)
-
(2006)
Molecular Cancer Therapeutics
, vol.5
, Issue.5
, pp. 1280-1289
-
-
Potapova, O.1
Laird, A.D.2
Nannini, M.A.3
Barone, A.4
Li, G.5
Moss, K.G.6
Cherrington, J.M.7
Mendel, D.B.8
-
32
-
-
0038476608
-
Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
-
DOI 10.1172/JCI200317929
-
Bergers G, Song S, Meyer-Morse N, Bergsland E, Hanahan D. Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors. J Clin Invest 2003; 111:1287-1295 (Pubitemid 36554699)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.9
, pp. 1287-1295
-
-
Bergers, G.1
Song, S.2
Meyer-Morse, N.3
Bergsland, E.4
Hanahan, D.5
-
34
-
-
33644864408
-
Phase II study of imatinib mesylate in chemotherapy refractory germ cell tumors expressing KIT
-
DOI 10.1097/01.coc.0000195086.47548.ef, PII 0000042120060200000004
-
Einhorn LH, Brames MJ, Heinrich MC, Corless CL, Madani A. Phase II study of imatinib mesylate inchemotherapy refractory germ cell tumors expressing C-KIT. Am J Clin Oncol 2006; 29:12-13 (Pubitemid 44356708)
-
(2006)
American Journal of Clinical Oncology: Cancer Clinical Trials
, vol.29
, Issue.1
, pp. 12-13
-
-
Einhorn, L.H.1
Brames, M.J.2
Heinrich, M.C.3
Corless, C.L.4
Madani, A.5
-
35
-
-
2442669093
-
Preclinical evaluation of the tyrosine kinase inhibitor SU11248 as a single agent and in combination with standard of care: Therapeutic agents for the treatment of breast cancer
-
Abrams TJ, Murray LJ, Pesenti E, et al. Preclinical evaluation of the tyrosine kinase inhibitor SU11248 as a single agent and in combination with standard of care: therapeutic agents for the treatment of breast cancer. Mol Cancer Ther 2003;2:1011-1021
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 1011-1021
-
-
Abrams, T.J.1
Murray, L.J.2
Pesenti, E.3
-
36
-
-
33644842476
-
Recent advances in management of patients with platinum-refractory testicular germ cell tumors
-
DOI 10.1002/cncr.21742
-
Kollmannsberger C, Nochols C, Bokemeyer C. Recent advances in management of patients with platinum-refractory testicular germ cell tumors. Cancer 2006;106:1217-1225 (Pubitemid 43363897)
-
(2006)
Cancer
, vol.106
, Issue.6
, pp. 1217-1226
-
-
Kollmannsberger, C.1
Nichols, C.2
Bokemeyer, C.3
|