A highly sensitive and robust UPLC-MS with electrospray ionization method for quantitation of taxifolin in rat plasma

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 18-19, 2009, Pages 1778-1786

  Wang, Xiaodan ^a   Xia, Hongjun ^a   Xing, Feng ^a   Deng, Guifeng ^a   Shen, Qi ^a   Zeng, Su ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Method validation; Pharmacokinetics; Rat plasma; Taxifolin; UPLC MS

Indexed keywords

ANALYTES; CONCENTRATION RANGES; ETHYL ACETATES; HIGHLY SENSITIVE; LIQUID/LIQUID EXTRACTION; LOWER LIMIT OF QUANTIFICATIONS; METHOD VALIDATION; ORAL ADMINISTRATION; PHARMACOKINETIC PARAMETERS; RAT PLASMA; TAXIFOLIN; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; UPLC-MS;

BIOCHEMISTRY; CHROMATOGRAPHIC ANALYSIS; ESTERS; IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PARAMETER ESTIMATION; PHARMACOKINETICS; PLASMA (HUMAN); PLASMAS;

ELECTROSPRAY IONIZATION;

ACETIC ACID ETHYL ESTER; PUERARIN; TAXIFOLIN;

ANIMAL EXPERIMENT; ARTICLE; DIAGNOSTIC ACCURACY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ISOLATION; DRUG STABILITY; ELECTROSPRAY MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; VALIDATION STUDY;

ANIMALS; CHROMATOGRAPHY, LIQUID; QUERCETIN; RATS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

RATTUS;

EID: 66149141859     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.04.037     Document Type: Article

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