The human receptor tyrosine kinase axl gene -promoter characterization and regulation of constitutive expression by Sp1, Sp3 and Cpg methylation

Bioscience Reports

Volumn 28, Issue 3, 2008, Pages 161-176

  Mudduluru, Giridhar ^a   Allgayer, Heike ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

5 aza 2 deoxycytidine (5 aza dC); Axl promoter; Axl receptor tyrosine kinase (RTK); CpG methylation; Specificity protein (Sp); Transcription

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AXL RECEPTOR TYROSINE KINASE; AZACITIDINE; DRUG DERIVATIVE; HYBRID PROTEIN; ONCOPROTEIN; PROTEIN TYROSINE KINASE; SMALL INTERFERING RNA; SP3 PROTEIN, HUMAN; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3; TUMOR PROTEIN;

ARTICLE; BIOSYNTHESIS; COLORECTAL TUMOR; CPG ISLAND; DNA METHYLATION; DRUG ANTAGONISM; DRUG EFFECT; ENZYME INDUCTION; GENE EXPRESSION REGULATION; GENETICS; HELA CELL; HUMAN; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROMOTER REGION; PROTEIN MOTIF; REPORTER GENE; RNA INTERFERENCE; SITE DIRECTED MUTAGENESIS; TUMOR CELL LINE;

AMINO ACID MOTIFS; AZACITIDINE; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; CPG ISLANDS; DNA METHYLATION; ENZYME INDUCTION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; HELA CELLS; HUMANS; MUTAGENESIS, SITE-DIRECTED; NEOPLASM PROTEINS; ONCOGENE PROTEINS; PROMOTER REGIONS, GENETIC; RECEPTOR PROTEIN-TYROSINE KINASES; RECOMBINANT FUSION PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SP1 TRANSCRIPTION FACTOR; SP3 TRANSCRIPTION FACTOR;

EID: 66149130903     PISSN: 01448463     EISSN: 15734935     Source Type: Journal    
DOI: 10.1042/BSR20080046     Document Type: Article

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