Purification, cloning, and functional characterization of a novel immunomodulatory protein from Antrodia camphorata (Bitter Mushroom) that exhibits TLR2-dependent NF-κB activation and M1 polarization within murine macrophages

Journal of Agricultural and Food Chemistry

Volumn 57, Issue 10, 2009, Pages 4130-4141

  Sheu, Fuu ^a   Chien, Po Jung ^b   Hsieh, Kuang Yang ^c   Chin, Kah Lock ^a   Huang, Wan Ting ^a   Tsao, Chiao Yin ^a   Chen, Yin Fang ^a   Cheng, Hui Chung ^a   Chang, Hui Hsin ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b CHINESE CULTURE UNIVERSITY   (Taiwan)

^c CHI MEI MEDICAL CENTER   (Taiwan)

Author keywords

Antrodia camphorata; Immunomodulatory protein; Macrophage activation; NF B; TLR2

Indexed keywords

ACA (IMMUNOMODULATORY PROTEIN), ANTRODIA CAMPHORATA; CHEMOKINE; CYTOKINE; FUNGAL PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOLOGIC FACTOR; TLR12 PROTEIN, MOUSE; TOLL LIKE RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL; ANTRODIA; ARTICLE; C57BL MOUSE; CELL LINE; CHEMISTRY; DRUG EFFECT; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; MACROPHAGE; MACROPHAGE ACTIVATION; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; MOUSE; MOUSE MUTANT; MYCELIUM; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

AMINO ACID SEQUENCE; ANIMALS; ANTRODIA; BASE SEQUENCE; CELL LINE; CHEMOKINES; CLONING, MOLECULAR; CYTOKINES; FUNGAL PROTEINS; GENE EXPRESSION; IMMUNOLOGIC FACTORS; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; MYCELIUM; NF-KAPPA B; TOLL-LIKE RECEPTORS; TRANSFECTION;

BASIDIOMYCOTA; FUNGI; MURINAE; TAIWANOFUNGUS CAMPHORATUS;

EID: 66149118510     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf900469a     Document Type: Article

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