A right-sided pathway involving FGF8ISnai1 controls asymmetric development of the proepicardium in the chick embryo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 18, 2009, Pages 7485-7490

  Schlueter, Jan ^a   Brand, Thomas ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Left right asymmetry; Pitx2; Tbx18; Venous pole morphogenesis

Indexed keywords

FIBROBLAST GROWTH FACTOR 8; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; PROTEIN NODAL; TRANSCRIPTION FACTOR PITX2; HOMEODOMAIN PROTEIN; SNAIL FAMILY TRANSCRIPTION FACTORS; T BOX TRANSCRIPTION FACTOR; TBX18 PROTEIN, CHICKEN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CHICK EMBRYO; COMPETITIVE INHIBITION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EPICARDIUM; GENE EXPRESSION; HEART DEVELOPMENT; MOLECULAR DYNAMICS; MORPHOGENESIS; NONHUMAN; PRIMITIVE STREAK; PRIORITY JOURNAL; PROEPICARDIUM; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; GENETICS; METABOLISM; PERICARDIUM; PHYSIOLOGY; PRENATAL DEVELOPMENT;

VERTEBRATA;

ANIMALS; CHICK EMBRYO; FIBROBLAST GROWTH FACTOR 8; HOMEODOMAIN PROTEINS; PERICARDIUM; T-BOX DOMAIN PROTEINS; TRANSCRIPTION FACTORS;

EID: 66149116841     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0811944106     Document Type: Article

References (52)

1. Raya A, Belmonte JC (2006) Left-right asymmetry in the vertebrate embryo: From early information to higher-level integration. Nat Rev Genet 7:283-293.
2. Schlueter J, Brand T (2007) Left-right axis development: Examples of similar and divergent strategies to generate asymmetric morphogenesis in chick and mouse embryos. Cytogenet Genome Res 117:256-267.
3. Lopez-Gracia ML, Ros MA (2007) Left-right asymmetry in vertebrate development. Adv Anat Embryol Cell Biol 188:1-121.
4. Levin M, et al. (2002) Asymmetries in H+/K+-ATPase and cell membrane potentials comprise a very early step in left-right patterning. Cell 111:77-89.
5. Levin M, Palmer AR (2007) Left-right patterning from the inside out: Widespread evidence for intracellular control. Bio Essays 29:271-287.
6. Hirokawa N, Tanaka Y, Okada Y, Takeda S (2006) Nodal flow and the generation of left-right asymmetry. Cell 125:33-45.
7. Shiratori H, Hamada H (2006) The left-right axis in the mouse: From origin to morphology. Development 133:2095-2104.
8. Levin M, et al. (1995) A molecular pathway determining left-right asymmetry in chick embryogenesis. Cell 82:803-814.
9. Gage P, Hoonkyo S, Camper S (1999) Dosage requirement of Pitx2 for development of multiple organs. Development 126:4643-4651.
10. Liu C, et al. (2001) Regulation of left-right asymmetry by thresholds of Pitx2c activity. Development 128:2039 -2048.
11. Liu C, et al. (2002) Pitx2c patterns anterior myocardium and aortic arch vessels and is required for local cell movement into atrioventricular cushions. Development 129:5081-5091.
12. Lu MF, et al. (1999) Function of Rieger syndrome gene in left-right asymmetry and craniofacial development. Nature 401:276 -278.
13. Davis NM, et al. (2008) The chirality of gut rotation derives from left-right asymmetric changes in the architecture of the dorsal mesentery. Dev Cell 15:134-145.
14. Kurpios NA, et al. (2008) The direction of gut looping is established by changes in the extracellular matrix and in cell-cell adhesion. Proc Natl Acad Sci USA 105:8499-8506.
15. Rodriguez-Leon J, et al. (2008) Pitx2 regulates gonad morphogenesis. Proc Natl Acad Sci USA 105:11242-11247.
16. Boettger T, Wittler L, Kessel M (1999) FGF8 functions in the specification of the right body side of the chick. Curr Biol 9:277-280.
17. Monsoro-Burq A, Le Douarin NM (2001) BMP4 plays a key role in left-right patterning in chick embryos by maintaining Sonic Hedgehog asymmetry. Mol Cell 7:789-799.
18. Ohuchi H, Kimura S, Watamoto M, Itoh N (2000) Involvement of fibroblast growth factor (FGF)18-FGF8 signaling in specification of left-right asymmetry and brain and limb development of the chick embryo. Mech Dev 95:55-66.
19. Patel K, Isaac A, Cooke J (1999) Nodal signalling and the roles of the transcription factors SnR and Pitx2 in vertebrate left-right asymmetry. Curr Biol 9:609 -612.
20. Männer J, Perez-Pomares JM, Macias D, Munoz-Chapuli R (2001) The origin, formation and developmental significance of the epicardium: A review. Cells Tissues Organs 169:89 -103.
21. Jahr M, Schlueter J, Brand T, Manner J (2008) Development of the proepicardium in Xenopus laevis. Dev Dyn 237:3088-3096.
22. Schulte I, et al. (2007) Morphological and molecular left-right asymmetries in the development of the proepicardium: A comparative analysis on mouse and chick embryos. Dev Dyn 236:684-695.
23. Schlueter J, Manner J, Brand T (2006) BMP is an important regulator of proepicardial identity in the chick embryo. Dev Biol 295:546 -558.
24. Campione M, et al. (2001) Pitx2 expression defines a left cardiac lineage of cells: Evidence for atrial and ventricular molecular isomerism in the iv/iv mice. Dev Biol 231:252-264.
25. Schlange T, et al. (2001) Chick CFC controls Lefty1 expression in the embryonic midline and nodal expression in the lateral plate. Dev Biol 234:376 -389.
26. Linask KK, etal. (2003) Effects of antisense misexpression of CFC on downstream flectin protein expression during heart looping. Dev Dyn 228:217-230.
27. Levy V, Khaner O (1998) Limited left-right cell migration across the midline of the gastrulating avian embryo. Dev Genet 23:175-184.
28. Kelly KA, Wei Y, Mikawa T (2002) Cell death along the embryo midline regulates left-right sidedness. Dev Dyn 224:238-244.
29. Isaac A, Sargent MG, Cooke J (1997) Control of vertebrate left-right asymmetry by a snail-related zinc finger gene. Science 275:1301-1304.
30. Pombal MA, et al. (2008) Epicardial development in lamprey supports an evolutionary origin ofthe vertebrate epicardium from an ancestral pronephric external glomerulus. Evol Dev 10:210-216.
31. Serluca FC (2008) Development of the proepicardial organ in the zebrafish. Dev Biol 315:18-27.
32. Meyers EN, Martin GR (1999) Differences in left-rightaxis pathways in mouse and chick: functions of FGF8 and SHH. Science 285:403-406.
33. Tanaka Y, Okada Y, Hirokawa N (2005) FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination. Nature 435:172-177.
34. Murray SA, Gridley T (2006) Snail family genes are required for left-right asymmetry determination, but not neural crest formation, in mice. Proc Natl Acad Sci USA 103:10300-10304.
35. Mommersteeg MT, et al. (2007) Molecular pathway for the localized formation of the sinoatrial node. Circ Res 100:354-362.
36. Anderson RH, Brown NA, Moorman AF (2006) Development and structures of the venous pole of the heart. Dev Dyn 235:2-9.
37. Shiratori H, Yashiro K, Shen MM, Hamada H (2006) Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs. Development 133:3015-3025.
38. Riddle RD, Johnson RL, Laufer E, Tabin C (1993) Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75:1401-1416.
39. Mandler M, Neubuser A (2004) FGF signaling is required for initiation of feather placode development. Development 131:3333-3343.
40. Marics I, et al. (2002) FGFR4 signaling is a necessarystep in limb muscle differentiation. Development 129:4559 -4569.
41. Fekete DM, Cepko CL (1993) Replication-competent retroviral vectors encoding alkaline phosphatase reveal spatial restriction of viral gene expression/transduction in the chick embryo. Mol Cell Biol 13:2604-2613.
42. Tavares AT, Andrade S, Silva AC, Belo JA (2007) Cerberus is a feedback inhibitor of Nodal asymmetric signaling in the chick embryo. Development 134:2051-2060.
43. Hamburger V, Hamilton H (1951) A series of normal stages in the development of the chick embryo. J Morphol 88:49 -92.
44. Chapman SC, Collignon J, Schoenwolf GC, Lumsden A (2001) Improved method for chick whole-embryo culture using a filter paper carrier. Dev Dyn 220:284-289.
45. Yu X, et al. (2001) Differential expression and functional analysis of Pitx2 isoforms in regulation of heart looping in the chick. Development 128:1005-1013.
46. Morales AV, et al. (2007) Snail genes at the crossroads of symmetric and asymmetric processes in the developing mesoderm. EMBO Rep 8:104-109.
47. Momose T, et al. (1999) Efficient targeting of gene expression in chick embryos by microelectroporation. Dev Growth Differ 41:335-344.
48. Andree B, etal. (1998) BMP-2 induces ectopic expression of cardiac lineage markers and interferes with somite formation in chicken embryos. Mech Dev 70:119 -131.
49. St Amand TR, et al. (1998) Cloning and expression pattern of chicken Pitx2: A new component in the SHH signaling pathway controlling embryonic heart looping. Biochem Biophys Res Commun 247:100-105.
50. Stern C (1998) Detection of multiple gene products simultaneously by in situ hybridization and immunohistochemistry in whole mounts of avian embryos. In Cellular and Molecular Procedures in Developmental Biology, eds Pablo F, Ferrus A, Stern C. (Academic, San Diego), pp. 223-243.
51. Acloque H, Wilkinson DG, Nieto MA (2008) In situ hybridization analysis of chick embryos in whole-mount and tissue sections. Methods Cell Biol 87:169 -185.
52. Soufan AT, et al. (2003) Three-dimensional reconstruction ofgene expression patterns during cardiac development. Physiol Genomics 13:187-195.