Acetylcholine induces Ca2+ signaling in chicken retinal pigmented epithelial cells during dedifferentiation

American Journal of Physiology - Cell Physiology

Volumn 296, Issue 5, 2009, Pages

  Sekiguchi Tonosaki, Mariko ^a,b,c   Obata, Masakatsu ^b   Haruki, Akira ^b   Himi, Toshiyuki ^c   Kosaka, Jun ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b iFORCOM   (Japan)

^c MUSASHINO UNIVERSITY   (Japan)

Author keywords

Ca2+ optical imaging; Fluo 4; L type Ca2+ channel; Nicotinic acetylcholine receptor; Transdifferentiation

Indexed keywords

CALCIUM ION; CHOLINERGIC RECEPTOR; MUSCARINE; 1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; ACETYLCHOLINE; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL STIMULATING AGENT; CHOLINERGIC RECEPTOR STIMULATING AGENT; DILTIAZEM; MUSCARINIC RECEPTOR; NICOTINE; NICOTINIC AGENT; NICOTINIC RECEPTOR;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL DEDIFFERENTIATION; CELL TRANSFER; CHICKEN; CONTROLLED STUDY; NONHUMAN; PIGMENT EPITHELIUM; PIGMENTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; CALCIUM SIGNALING; CELL CULTURE; CELL DIFFERENTIATION; CHICK EMBRYO; CYTOLOGY; DRUG EFFECT; METABOLISM; PHYSIOLOGY; PRENATAL DEVELOPMENT;

3-PYRIDINECARBOXYLIC ACID, 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-(TRIFLUOROMETHYL)PHENYL)-, METHYL ESTER; ACETYLCHOLINE; ANIMALS; CALCIUM; CALCIUM CHANNEL AGONISTS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CELL DEDIFFERENTIATION; CELL DIFFERENTIATION; CELLS, CULTURED; CHICK EMBRYO; CHICKENS; CHOLINERGIC AGENTS; DILTIAZEM; NICOTINE; NICOTINIC AGONISTS; RECEPTORS, MUSCARINIC; RECEPTORS, NICOTINIC; RETINAL PIGMENT EPITHELIUM;

EID: 66149099597     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00423.2008     Document Type: Article

References (39)

1. Agata K, Kobayashi H, Itoh Y, Mochii M, Sawada K, Eguchi G. Genetic characterization of the multipotent dedifferentiated state of pigmented epithelial cells in vitro. Development 118: 1025-1030, 1993.
2. Coulombre JL, Coulombre AJ. Regeneration of neural retina from the pigmented epithelium in the chick embryo. Dev Biol 12: 79-92, 1965.
3. 2+ channels in neural stem/progenitor cell differentiation. Eur J Neurosci 23: 935-944, 2006.
4. Dräger UC. Calcium binding in pigmented and albino eyes. Proc Natl Acad Sci USA 82: 6716-6720, 1985.
5. Eguchi G. Cellular and molecular background of Wolffian lens regeneration. In: Regulatory Mechanisms in Developmental Processes, edited by Eguchi G, Okada TS, Saxen L. Limerick, Ireland: Elsevier, p. 147-158, 1988.
6. Eguchi G. Transdifferentiation as the basis of eye lens regeneration. In: Cellular and Molecular Basis of Regeneration: From Invertebrates to Humans, edited by Ferretti P, Geraudie J. Chichester, UK: John Wiley, p. 207-228, 1998.
7. Fischer AJ, McKinnon LA, Nathanson NM, Stell WK. Identification and localization of muscarinic acetylcholine receptors in the ocular tissues of the chick. J Comp Neurol 392: 273-284, 1998.
8. Friedman Z, Hackett SF, Campochiaro PA. Human retinal pigment epithelial cells possess muscarinic receptors coupled to calcium mobilization. Brain Res 446: 11-16, 1988.
9. Hamburger V, Hamilton HL. A series of normal stages in the development of the chick embryo. J Morphol 88: 49-92, 1951.
10. Hyuga M, Kodama R, Eguchi G. Basic fibroblast growth factor as one of the essential factors regulating lens transdifferentiation of pigmented epithelial cells. Int J Dev Biol 37: 319-326, 1993.
11. Itoh Y, Eguchi G. In vitro analysis of cellular metaplasia from pigmented epithelial cells to lens phenotypes: a unique model system for studying cellular and molecular mechanisms of "transdifferentiation". Dev Biol 115: 353-362, 1986.
12. King-Smith C, Chen P, Garcia D, Rey H, Burnside B. Calcium-independent regulation of pigment granule aggregation and dispersion in teleost retinal pigment epithelial cells. J Cell Sci 109: 33-43, 1996.
13. Kosaka J, Watanabe K, Eguchi G. Transdifferentiation of chicken retinal pigmented epithelial cells in serum-free culture. Exp Eye Res 55: 261-267, 1992.
14. Mangini NJ, Haugh-Scheidt L, Valle JE, Cragoe EJ Jr, Ripps H, Kennedy BG. Sodium-calcium exchanger in cultured human retinal pigment epithelium. Exp Eye Res 65: 821-834, 1997.
15. Mochii M, Mazaki Y, Mizuno N, Hayashi H, Eguchi G. Role of Mitf in differentiation and transdifferentiation of chicken pigmented epithelial cell. Dev Biol 193: 47-62, 1998.
16. Naruoka H, Kojima R, Ohmasa M, Layer PG, Saito T. Transient muscarinic calcium mobilisation in transdifferentiating as in reaggregating embryonic chick retinae. Brain Res Dev Brain Res 143: 233-244, 2003.
17. Oikawa H, Nakamichi N, Kambe Y, Ogura M, Yoneda Y. An increase in intracellular free calcium ions by nicotinic acetylcholine receptors in a single cultured rat cortical astrocyte. J Neurosci Res 79: 535-544, 2005.
18. Okada TS. Transdifferentiation: Flexibility in Cell Differentiation. Oxford, UK: Oxford Univ. Press, 1991.
19. Osborne NN, FitzGibbon F, Schwartz G. Muscarinic acetylcholine receptor-mediated phosphoinositide turnover in cultured human retinal pigment epithelium cells. Vision Res 31: 1119-1127, 1991.
20. Park CM, Hollenberg MJ. Induction of retinal regeneration in vivo by growth factors. Dev Biol 148: 322-333, 1991.
21. 2+ signalling and gap junction coupling within and between pigment epithelium and neural retina in the developing chick. Eur J Neurosci 19: 2435-2445, 2004.
22. Phatarpekar PV, Durdan SF, Copeland CM, Crittenden FL, Neece JD, García DM. Molecular and pharmacological characterization of muscarinic receptors in retinal pigment epithelium: role in light adaptive pigment movement. J Neurochem 95: 1504-1520, 2005.
23. 2+ channels in retinal pigment epithelial cells regulate vascular endothelial growth factor secretion rates in health and disease. Mol Vis 13: 443-456, 2007.
24. 2+ channel expression in cultured newt retinal pigment epithelial cells: comparison with neuronal types of ion channels. J Neurobiol 32: 377-390, 1997.
25. Sartiani L, Bettiol E, Stillitano F, Mugelli A, Cerbai E, Jaconi ME. Developmental changes in cardiomyocytes differentiated from human embryonic stem cells: a molecular and electrophysiological approach. Stem Cells 25: 1136-1144, 2007.
26. Schmidt H, Oettling G, Kaufenstein T, Hartung G, Drews U. Intracellular calcium mobilization on stimulation of the muscarinic cholinergic receptor in chick limb bud cells. Roux's Arch Dev Biol 194: 44-49, 1984.
27. 2+ channel current by diltiazem in human mesenteric arterial myocytes. Eur J Pharmacol 360: 81-90, 1998.
28. 2+ rise in the embryonic chick retina. J Neurobiol 34: 113-125, 1998.
29. Sun G, Asami M, Ohta H, Kosaka J, Kosaka M. Retinal stem/progenitor properties of iris pigment epithelial cells. Dev Biol 289: 243-252, 2006.
30. Tikhonov DB, Zhorov BS. Molecular modeling of benzothiazepine binding in the L-type calcium channel. J Biol Chem 283: 17594-17604, 2008.
31. Tsonis PA, Jang W, Rio-Tsonis KD, Eguchi G. A unique aged human retinal pigmented epithelial cell line useful for studying lens differentiation in vitro. Int J Dev Biol 45: 753-758, 2001.
32. Uechi Y, Yoshioka H, Morikawa D, Ohta Y. Stability of membrane potential in heart mitochondria: single mitochondrion imaging. Biochem Biophys Res Commun 344: 1094-1101, 2006.
33. Wessler I, Kirkpatrick CJ. Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans. Br J Pharmacol 154: 1558-1571, 2008.
34. Wheeler DG, Barrett CF, Tsien RW. L-type calcium channel ligands block nicotine-induced signaling to CREB by inhibiting nicotinic receptors. Neuropharmacology 51: 27-36, 2006.
35. Yamashita M, Fukuda Y. Calcium channels and GABA receptors in the early embryonic chick retina. J Neurobiol 24: 1600-1614, 1993.
36. 2+ release. FEBS J 273: 3585-3597, 2006.
37. Yamashita M, Yoshimoto Y, Fukuda Y. Muscarinic acetylcholine responses in the early embryonic chick retina. J Neurobiol 25: 1144-1153, 1994.
38. Zhao S, Thornquist SC, Barnstable CJ. In vitro transdifferentiation of embryonic rat retinal pigment epithelium to neural retina. Brain Res 677: 300-310, 1995.
39. Zwart R, Vijverberg HPM. Potentiation and inhibition of neuronal nicotinic receptors by atropine: competitive and noncompetitive effects. Mol Pharmacol 52: 886-895, 1997.